Catalog No.
YHE41601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile102-Val309
Predicted molecular weight
26.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43355
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MAGEA1, CT1.1, Cancer/testis antigen 1.1, MAGE1A, MAGE1, Antigen MZ2-E, Melanoma-associated antigen 1, MAGE-1 antigen
A virus based vaccine combined with IL12 gene therapy eradicates aggressive melanoma., PMID:40442309
Expression of Cancer-Testis Antigens MAGE-A1, MAGE-A4, NY-ESO-1 and PRAME in Bone and Soft Tissue Sarcomas: The Experience From a Single Center in China., PMID:40152485
Proceedings of the National Cancer Institute Workshop on combining immunotherapy with radiotherapy: challenges and opportunities for clinical translation., PMID:40049206
A panel of cancer testis antigens in squamous cell carcinoma of the lung, head and neck, and esophagus: implication for biomarkers and therapeutic targets., PMID:39864021
Diagnostic value of multi-tumor-associated autoantibody expression in esophageal squamous cell carcinoma and correlation of clinical features., PMID:39744640
MLLT3 Regulates Melanoma Stemness and Progression by Inhibiting HMGB1 Nuclear Entry and MAGEA1 M5C Modification., PMID:39716999
Abscopal response in a patient with fibrolamellar hepatocellular carcinoma following radiotherapy., PMID:39709209
Evaluation of MAGE-A4 expression in breast cancer and its impact on prognosis., PMID:39704015
Next-Generation Sequencing-Based MSI Scoring Predicts Benefit in Mismatch Repair-Deficient Tumors Treated with Nivolumab: Follow-up on NCI-MATCH Arm Z1D., PMID:39670863
The clinical value of combined detection of seven lung cancer-related autoantibodies in assisting the diagnosis of non-small-cell lung cancer., PMID:39360656
Pyrimidine-Dependent UV-Mediated Cross-Linking Magnifies Minor Genetic or Epigenetic Changes in Clinical Samples., PMID:39039866
First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors., PMID:39038917
Pulsed electric field induces exocytosis and overexpression of MAGE antigens in melanoma., PMID:38822068
An Engineered M13 Filamentous Nanoparticle as an Antigen Carrier for a Malignant Melanoma Immunotherapeutic Strategy., PMID:38400008
Expression of MAGE A1 to MAGE A10 in the Forceps Biopsy and Bronchoalveolar Lavage Specimens from Patients with the Central Lung Tumor., PMID:38285780
Autologous engineered T cell receptor therapy in advanced cancer., PMID:38114231
Diagnosis of Malignant Pulmonary Nodules Using a Combination of Tumor-associated Autoantibodies and Computed Tomography., PMID:38054473
[Evaluation of the application value of seven tumor-associated autoantibodies in non-small cell lung cancer based on machine learning algorithms]., PMID:38008573
Diagnostic performance of anti-MAGEA family protein autoantibodies in esophageal squamous cell carcinoma., PMID:37866309
Expression of four cancer-testis antigens in TNBC indicating potential universal immunotherapeutic targets., PMID:37610673
Development of novel self-assembled vaccines based on tumour-specific antigenic peptide and TLR2 agonist for effective breast cancer immunotherapy via activating CD8+ T cells and enhancing their function., PMID:36946150
Genomic Profiling Reveals the Variant Landscape of Sporadic Parathyroid Adenomas in Chinese Population., PMID:36611251
Systemic T-cell and humoral responses against cancer testis antigens in hepatocellular carcinoma patients., PMID:36211805
Epigenomic and somatic mutations of pituitary tumors with clinical and pathological correlations in 111 patients., PMID:36161330
Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy., PMID:35803260
MAGEA1 and hTERT Peptide Treatment Improves the Potency of The Dendritic Cell- Cytotoxic T Lymphocytes (DC-CTL) Immunotherapy in DAC Treated Acute Myeloid Leukemia., PMID:35281868
[Clinical value of tumor-associated autoantibodies in diagnosis of early non-small cell lung cancer]., PMID:34963239
Phase I/II trial of a long peptide vaccine (LPV7) plus toll-like receptor (TLR) agonists with or without incomplete Freund's adjuvant (IFA) for resected high-risk melanoma., PMID:34413169
Immunological and functional aspects of MAGEA3 cancer/testis antigen., PMID:33931137
Analysis of DNA methylation-driven genes for predicting the prognosis of patients with colorectal cancer., PMID:33203797
A new tool for early diagnosis of rheumatoid arthritis using combined biomarkers; synovial MAGE-1 mRNA and serum anti-CCP and RF., PMID:33088399
A comprehensive analysis of the MAGE family as prognostic and diagnostic markers for hepatocellular carcinoma., PMID:32941982
Clinical significance of long non-coding RNA DUXAP8 and its protein coding genes in hepatocellular carcinoma., PMID:32922554
[Regulation of Gene Expression of Cancer/Testis Antigens in Colorectal Cancer Patients]., PMID:32799221
CTLA‑4 blockade combined with 5‑aza‑2'‑deoxycytidine enhances the killing effect of MAGE‑A family common antigen peptide‑specific cytotoxic T cells on breast cancer., PMID:32700745
Stem signatures associated antibodies yield early diagnosis and precise prognosis predication of patients with non-small cell lung cancer., PMID:32691153
Preparation of a new combination nanoemulsion-encapsulated MAGE1-MAGE3-MAGEn/HSP70 vaccine and study of its immunotherapeutic effect., PMID:32321658
Synthetic tumor-specific antigenic peptides with a strong affinity to HLA-A2 elicit anti-breast cancer immune response through activating CD8+ T cells., PMID:31968280
The diagnostic efficiency of seven autoantibodies in lung cancer., PMID:31764214
The clinical significance of methylation of MAGE-A1 and-A3 promoters and expression of DNA methyltransferase in patients with laryngeal squamous cell carcinoma., PMID:31732299
MAGE-A1 in lung adenocarcinoma as a promising target of chimeric antigen receptor T cells., PMID:31640756
Antibody Responses to Cancer Antigens Identify Patients with a Poor Prognosis among HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinoma Patients., PMID:31444248
Patterns of antibody responses to nonviral cancer antigens in head and neck squamous cell carcinoma patients differ by human papillomavirus status., PMID:31407331
Expressions of melanoma-associated antigen A1 as a prognostic factor in Chinese patients with resectable oesophageal squamous cell carcinoma., PMID:31169876
Tomato lectin-modified nanoemulsion-encapsulated MAGE1-HSP70/SEA complex protein vaccine: Targeting intestinal M cells following peroral administration., PMID:31029887
Liposomes targeted to MHC-restricted antigen improve drug delivery and antimelanoma response., PMID:30988609
Performance Evaluation of an Enzyme-Linked Immunosorbent Assay for Seven Autoantibodies in Lung Cancer., PMID:30969073
[Early diagnosis of subtype in early clinical stage lung adenocarcinoma by using an autoantibody panel and computed tomography]., PMID:30669764
Expression of cancer/testis antigens in cutaneous melanoma: a systematic review., PMID:30615012
Overexpression of cancer-testis antigen melanoma-associated antigen A1 in lung cancer: A novel biomarker for prognosis, and a possible target for immunotherapy., PMID:30569450
For research use only. Not for human or drug use.
