Catalog No.
YHE42501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met111-Val429
Predicted molecular weight
37.85 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43364
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cancer/testis antigen 1.11, CT1.11, MAGE11, MAGEA11, Melanoma-associated antigen 11, MAGE-11 antigen
Construction of a multigenic diagnostic, prognostic, and immune infiltration model with methylation-associated regulators in esophageal squamous cell carcinoma., PMID:40400969
A panel of cancer testis antigens in squamous cell carcinoma of the lung, head and neck, and esophagus: implication for biomarkers and therapeutic targets., PMID:39864021
Homeobox regulator Wilms Tumour 1 is displaced by androgen receptor at cis-regulatory elements in the endometrium of PCOS patients., PMID:38745948
MAGE-A11 is a potential prognostic biomarker and immunotherapeutic target in gastric cancer., PMID:38180746
Hyperandrogenism and Its Possible Effects on Endometrial Receptivity: A Review., PMID:37569402
Identification of Cancer/Testis Antigens Related to Gastric Cancer Prognosis Based on Co-Expression Network and Integrated Transcriptome Analyses., PMID:37057240
Metastasis-Related Signature for Clinically Predicting Prognosis and Tumor Immune Microenvironment of Osteosarcoma Patients., PMID:36807122
The Disruption of Mage-11 Gene via CRISPR/Cas9 Method Induced Apoptosis in the in vitro Model of Prostate Cancer., PMID:36804154
Molecular Characteristics of Bladder Tumor: Increased Gene Expression of MAGE-A6 and MAGE-A11 with Decreased MicroRNA-34a and MicroRNA-125b., PMID:36341564
Epigenomic and somatic mutations of pituitary tumors with clinical and pathological correlations in 111 patients., PMID:36161330
Blockade of TIM-3 and PD-1 enhances the antitumor effects of MAGE-A11 antigen-specific cytotoxic T lymphocytes., PMID:35710477
Co-expression of cancer-testis antigens of MAGE-A6 and MAGE-A11 is associated with tumor aggressiveness in patients with bladder cancer., PMID:35022469
Cytotoxic T-lymphocyte elicited therapeutic vaccine candidate targeting cancer against MAGE-A11 carcinogenic protein., PMID:33169789
Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases., PMID:33004795
High infiltration of B cells in tertiary lymphoid structures, TCR oligoclonality, and neoantigens are part of esophageal squamous cell carcinoma microenvironment., PMID:32827331
Epigenetic modulation combined with PD-1/PD-L1 blockade enhances immunotherapy based on MAGE-A11 antigen-specific CD8+T cells against esophageal carcinoma., PMID:32529260
MAGE-A11 Expression Predicts Patient Prognosis in Head and Neck Squamous Cell Carcinoma., PMID:32161495
A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3' End Processing Complex., PMID:31980388
Delayed endometrial decidualisation in polycystic ovary syndrome; the role of AR-MAGEA11., PMID:31256208
Demethylation-mediated upregulation of melanoma-associated antigen-A11 correlates with malignant progression of esophageal squamous cell carcinoma., PMID:31155488
Expression and prognostic significance of MAGE-A11 and transcription factors (SP1,TFCP2 and ZEB1) in ESCC tissues., PMID:31126819
Analysis of the function of MAGE-A in esophageal carcinoma by bioinformatics., PMID:31124967
Design of Artificial Immunogens Containing Melanoma-associated T-cell Epitopes., PMID:30421674
Expression and Prognostic Relevance of GAGE1 and XAGE1 Cancer/Testis Antigens in Head and Neck Squamous Cell Carcinoma., PMID:29577858
Evolution of Melanoma Antigen-A11 (MAGEA11) During Primate Phylogeny., PMID:29574604
MAGE-A11 is activated through TFCP2/ZEB1 binding sites de-methylation as well as histone modification and facilitates ESCC tumor growth., PMID:29423052
Melanoma-associated antigen A11 reduces erlotinib and afatinib efficacy in head and neck cancer., PMID:29311018
MAGE-A11 expression contributes to cisplatin resistance in head and neck cancer., PMID:29034444
Functional interaction between co-expressed MAGE-A proteins., PMID:28542476
Zebularine Treatment Induces MAGE-A11 Expression and Improves CTL Cytotoxicity Using a Novel Identified HLA-A2-restricted MAGE-A11 Peptide., PMID:28486273
Androgen receptor regulation by histone methyltransferase Suppressor of variegation 3-9 homolog 2 and Melanoma antigen-A11., PMID:28042025
Up-Regulation of Follistatin-Like 1 By the Androgen Receptor and Melanoma Antigen-A11 in Prostate Cancer., PMID:27976415
Melanoma antigen-A11 regulates substrate-specificity of Skp2-mediated protein degradation., PMID:27720894
Prognostic Significance of MAGE-A11 in Esophageal Squamous Cell Carcinoma and Identification of Related Genes Based on DNA Microarray., PMID:27362547
Expression of MAGE-A1, -A9, -A11 in laryngeal squamous cell carcinoma and their prognostic significance: a retrospective clinical study., PMID:26766421
Post-translational Down-regulation of Melanoma Antigen-A11 (MAGE-A11) by Human p14-ARF Tumor Suppressor., PMID:26330556
Enhancing lung cancer diagnosis: electrochemical simultaneous bianalyte immunosensing using carbon nanotubes-chitosan nanocomposite., PMID:25024132
Expressions of MAGE-A9 and MAGE-A11 in breast cancer and their expression mechanism., PMID:24316396
Proto-oncogene activity of melanoma antigen-A11 (MAGE-A11) regulates retinoblastoma-related p107 and E2F1 proteins., PMID:23853093
DNA methylation and nucleosome occupancy regulate the cancer germline antigen gene MAGEA11., PMID:23839233
Efficacy of cetuximab and panitumumab in oral squamous cell carcinoma cell lines: prognostic value of MAGE-A subgroups for treatment success., PMID:23375534
Melanoma antigen-A11 (MAGE-A11) enhances transcriptional activity by linking androgen receptor dimers., PMID:23172223
Expression of MAGE-A11 in breast cancer tissues and its effects on the proliferation of breast cancer cells., PMID:23064813
Primate-specific melanoma antigen-A11 regulates isoform-specific human progesterone receptor-B transactivation., PMID:22891251
Cross-immunizing potential of tumor MAGE-A epitopes recognized by HLA-A*02:01-restricted cytotoxic T lymphocytes., PMID:22831976
Androgen receptor exon 1 mutation causes androgen insensitivity by creating phosphorylation site and inhibiting melanoma antigen-A11 activation of NH2- and carboxyl-terminal interaction-dependent transactivation., PMID:22334658
Expressions of MAGE-A10 and MAGE-A11 in breast cancers and their prognostic significance: a retrospective clinical study., PMID:22198676
Analysis of interdomain interactions of the androgen receptor., PMID:21796524
Gain in transcriptional activity by primate-specific coevolution of melanoma antigen-A11 and its interaction site in androgen receptor., PMID:21730049
Transcriptional synergy between melanoma antigen gene protein-A11 (MAGE-11) and p300 in androgen receptor signaling., PMID:20448036
For research use only. Not for human or drug use.
