Catalog No.
YHE39501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala155-Gln355
Predicted molecular weight
24.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43116
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PTGER2, PGE2 receptor EP2 subtype, Prostaglandin E2 receptor EP2 subtype, Prostanoid EP2 receptor, PGE receptor EP2 subtype
Developing a risk assessment model for treatment-resistant schizophrenia: The role of niacin receptor GPR109A and prostaglandin receptors DP1, EP2, and EP4 in the niacin-induced flushing pathway., PMID:40220605
Distinct roles of PGE2 signaling via EP2 and EP4 in circulating pDCs: Implications for immune modulation in the tumor microenvironment., PMID:40116121
Acetylsalicylic acid aggravates anaphylaxis in a PGE2-dependent manner., PMID:40026245
Identification of novel biomarkers associated with immune infiltration in major depression disorder and atopic dermatitis., PMID:39953304
Repurposing of dipeptidyl peptidase FDA-approved drugs in Alzheimer's disease using network pharmacology and in-silico approaches., PMID:39938415
Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling., PMID:39920161
Prostaglandin E2-EP2/EP4 signaling induces immunosuppression in human cancer by impairing bioenergetics and ribosome biogenesis in immune cells., PMID:39487111
Prostaglandin E Receptor 2 (EP2) Dysregulation in Allergic Fungal Rhinosinusitis Nasal Polyp Epithelium., PMID:39487665
Prostaglandin E2 regulates the plasminogen activator pathway in human endometrial endothelial cells: a new in vitro model to investigate heavy menstrual bleeding., PMID:39038609
In vitro effect of visfatin on endocrine functions of the porcine corpus luteum., PMID:38926439
COX2-dependent suppression of anticancer immunity., PMID:38821853
PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function., PMID:38658764
The possible regulatory role of miR-514 and miR-642b in cumulus cells on the oocyte maturation in patients with polycystic ovary syndrome., PMID:38367330
Pharmacological evidence that the inhibitory effects of prostaglandin E2 are mediated by the EP2 and EP4 receptors in human neutrophils., PMID:38345417
Surface CD52, CD84, and PTGER2 mark mature PMN-MDSCs from cancer patients and G-CSF-treated donors., PMID:38242120
N6-methyladenosine Methyltransferase METTL3 Enhances PTGER2 Expression to Increase Ovarian Cancer Stemness and Chemoresistance., PMID:37796697
Identifying G protein-coupled receptors involved in adipose tissue function using the innovative RNA-seq database FATTLAS., PMID:37766984
In vitro cross-talk between metastasis-competent circulating tumor cells and platelets in colon cancer: a malicious association during the harsh journey in the blood., PMID:37601099
A novel angiogenesis-related scoring model predicts prognosis risk and treatment responsiveness in diffuse large B-cell lymphoma., PMID:37402040
Complementary roles of EP2 and EP4 receptors in malignant glioma., PMID:37232020
Fractalkine Improves the Expression of Endometrium Receptivity-Related Genes and Proteins at Desferrioxamine-Induced Iron Deficiency in HEC-1A Cells., PMID:37175630
A senescence-based prognostic gene signature for colorectal cancer and identification of the role of SPP1-positive macrophages in tumor senescence., PMID:37090726
Role of COX-2/PGE2 signaling pathway in the apoptosis of rat ovarian granulosa cells induced by MEHP., PMID:36889213
["Component-target-efficacy" network analysis and experimental verification of Qingkailing Oral Preparation]., PMID:36725269
Investigations of plausible pharmacodynamics supporting the antispasmodic, bronchodilator, and antidiarrheal activities of Berberis lycium Royle. Via in silico, in vitro, and in vivo studies., PMID:36587881
Prostaglandins differentially modulate mucosal-associated invariant T-cell activation and function according to stimulus., PMID:36541521
Identification of Biomarkers That Modulate Osteogenic Differentiation in Mesenchymal Stem Cells Related to Inflammation and Immunity: A Bioinformatics-Based Comprehensive Study., PMID:36145314
Prostaglandin E receptor 2 mediates the inducible effects of prostaglandin E2 on expression of growth factors and enzymes in cattle endometrial epithelial cells and explants., PMID:36131609
Increased COX-2 after ureter obstruction attenuates fibrosis and is associated with EP2 receptor upregulation in mouse and human kidney., PMID:35543087
Polymorphisms of COX/PEG2 pathway-related genes are associated with the risk of lung cancer: A case-control study in China., PMID:35430434
Intact prostaglandin signaling through EP2 and EP4 receptors in stromal progenitor cells is required for normal development of the renal cortex in mice., PMID:35037469
The EP2 agonist, omidenepag, alters the physical stiffness of 3D spheroids prepared from human corneal stroma fibroblasts differently depending on the osmotic pressure., PMID:34914140
Identification of ACOT13 and PTGER2 as novel candidate genes of autosomal dominant polycystic kidney disease through whole exome sequencing., PMID:34886911
Alpha-Synuclein, cyclooxygenase-2 and prostaglandins-EP2 receptors as neuroinflammatory biomarkers of autism spectrum disorders: Use of combined ROC curves to increase their diagnostic values., PMID:34742290
Proliferation of bovine endometrial epithelial cells is promoted by prostaglandin E2-PTGER2 signaling through cell cycle regulation., PMID:34740034
Prostaglandin E2 increases the expression of cyclooxygenase-2 in cultured rat microglia., PMID:34610503
Single-cell analysis of prostaglandin E2-induced human decidual cell in vitro differentiation: a minimal ancestral deciduogenic signal†., PMID:34591094
Investigations on the potential role of prostaglandin E2 in canine uterine inertia., PMID:34544012
Myeloid-Derived Suppressor Cells Dampen Airway Inflammation Through Prostaglandin E2 Receptor 4., PMID:34322123
Novel multi-strain probiotics reduces Pasteurella multocida induced fowl cholera mortality in broilers., PMID:33903662
The differential functional coupling of phosphodiesterase 4 to human DP and EP2 prostanoid receptors stimulated with PGD2 or PGE2., PMID:33786738
Prostaglandin F2α and EP2 agonists, and a ROCK inhibitor modulate the formation of 3D organoids of Grave's orbitopathy related human orbital fibroblasts., PMID:33587909
Polymorphisms rs2745557 in PTGS2 and rs2075797 in PTGER2 are associated with the risk of chronic obstructive pulmonary disease development in a Tunisian cohort., PMID:33545665
Elevated IL-38 inhibits IL-23R expression and IL-17A production in thyroid-associated ophthalmopathy., PMID:33383445
Expression of trophoblast derived prostaglandin E2 receptor 2 (EP2) is reduced in patients with recurrent miscarriage and EP2 regulates cell proliferation and expression of inflammatory cytokines., PMID:33011635
The role of EP-2 receptor expression in cervical intraepithelial neoplasia., PMID:32851536
PGE2 accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking., PMID:32820026
The molecular, functional and phylogenetic characterization of PGE2 receptors reveals their different roles in the immune response of the teleost fish gilthead seabream (Sparus aurata L.)., PMID:32738336
Upregulated proteoglycan-related signaling pathways in fluid flow shear stress-treated podocytes., PMID:32628542
Syntenin-1 promotes colorectal cancer stem cell expansion and chemoresistance by regulating prostaglandin E2 receptor., PMID:32595209
For research use only. Not for human or drug use.
