Catalog No.
YHE05701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp641
Predicted molecular weight
72.68 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P34931
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HSP70-Hom, Heat shock 70 kDa protein 1L, Heat shock 70 kDa protein 1-like, HSPA1L, Heat shock 70 kDa protein 1-Hom
Exploring heat shock protein-related biomarkers and subgroups in osteoarthritis using Gene Expression Omnibus data sets., PMID:40474128
Recent insights into depression from transcriptomic analysis., PMID:40376285
Identification of key genes related to unilateral cryptorchidism in sheep by comprehensive transcriptomics and proteomics analyses., PMID:39972276
VEGFR3 mitigates hypertensive nephropathy by enhancing mitophagy via regulating crotonylation of HSPA1L., PMID:39875989
Comprehensive analysis of heat shock protein 110, 90, 70, 60 families and tumor immune microenvironment characterization in clear cell renal cell carcinoma., PMID:39747468
Deciphering the role of heat shock protein HSPA1L: biomarker discovery and prognostic insights in Parkinson's disease and glioma., PMID:39454876
Validation and functional follow-up of cervical cancer risk variants at the HLA locus., PMID:39101335
Genetic associations in ankylosing spondylitis: circulating proteins as drug targets and biomarkers., PMID:38835753
The regulation of MFG-E8 on the mitophagy in diabetic sarcopenia via the HSPA1L-Parkin pathway and the effect of D-pinitol., PMID:38553831
A comparative study on effect of heat stress on physiological and cellular responses of crossbred cattle and riverine buffalo in subtropical region of India., PMID:37495744
Identification of immunodiagnostic blood biomarkers associated with spinal cord injury severity., PMID:37063890
Analysis of signaling cascades from myeloma cells treated with pristimerin., PMID:36858733
[Identify the characteristic genes of dilated cardiomyopathy and immune cell infiltration based on bioinformatics and machine learning]., PMID:36631012
Analysis of the heat shock protein 70 (HSP70) genetic variants in nonsegmental vitiligo patients., PMID:36345598
Cryopreservation did not affect sperm DNA methylation levels of genes related to fertilization and embryonic development of cynomolgus macaque (Macaca fascicularis)., PMID:35926569
SMAD4 rs10502913 is Significantly Associated with Chronic Obstructive Pulmonary Disease in a Chinese Han Population: A Case-Control Study., PMID:35898699
Unfolded protein response is involved in the metabolic and apoptotic regulation of oral squamous cell carcinoma., PMID:35791990
Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer., PMID:35307764
Pregnancy exposure to phthalates and DNA methylation in male placenta - An epigenome-wide association study., PMID:35032864
Expressions of HSPA1L and HSPA9 are associated with poor sperm quality of low-motility spermatozoa in fertile men., PMID:34796524
Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth., PMID:34429451
Application of proteomic to investigate the different degrees of meat tenderness in Nellore breed., PMID:34303863
Transcriptomic insights into the zinc homeostasis of MCF-7 breast cancer cells via next-generation RNA sequencing., PMID:33960390
The association of heat shock protein genetic polymorphisms with age-related hearing impairment in Taiwan., PMID:33926545
A Vaspin-HSPA1L complex protects proximal tubular cells from organelle stress in diabetic kidney disease., PMID:33742129
[To the question of genetic predisposition to the development of professional sensorineural hearing loss]., PMID:33720645
SARS-CoV-2 Infection-Induced Promoter Hypomethylation as an Epigenetic Modulator of Heat Shock Protein A1L (HSPA1L) Gene., PMID:33679887
Prognostic Significance of the Hsp70 Gene Family in Colorectal Cancer., PMID:33600380
The adverse events of haematopoietic stem cell transplantation are associated with gene polymorphism within human leukocyte antigen region., PMID:33446692
Tyrosinase-mediated melanogenesis in melanoma cells: Array comparative genome hybridization integrating proteomics and bioinformatics studies., PMID:33359255
The Cellular Prion Protein: A Promising Therapeutic Target for Cancer., PMID:33276687
HSPA1L Enhances Cancer Stem Cell-Like Properties by Activating IGF1Rβ and Regulating β-Catenin Transcription., PMID:32971893
Prospects for gene introgression or gene editing as a strategy for reduction of the impact of heat stress on production and reproduction in cattle., PMID:32622199
Cell-Specific Transcriptional Responses to Heat Shock in the Mouse Utricle Epithelium., PMID:32528249
Functional diversity between HSP70 paralogs caused by variable interactions with specific co-chaperones., PMID:32284329
The heat shock protein family gene Hspa1l in male mice is dispensable for fertility., PMID:32231871
HSPA1L rs1061581 polymorphism is associated with the risk of preeclampsia in Han Chinese women., PMID:32039449
Effect of SNPs in HSP Family Genes, Variation in the mRNA and Intracellular Hsp Levels in COPD Secondary to Tobacco Smoking and Biomass-Burning Smoke., PMID:31993068
Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the HSPA1L-mitophagy pathway., PMID:31965731
HSPA1A, HSPA1L and TRAP1 heat shock genes may be associated with prognosis in ovarian epithelial cancer., PMID:31897148
An overview of research trends and genetic polymorphisms for noise-induced hearing loss from 2009 to 2018., PMID:31696427
MAPKAP kinase 2-mediated phosphorylation of HspA1L protects male germ cells from heat stress-induced apoptosis., PMID:31642047
Melatonin Enhances Mitophagy by Upregulating Expression of Heat Shock 70 kDa Protein 1L in Human Mesenchymal Stem Cells under Oxidative Stress., PMID:31540288
HSPA1L and HSPA1B gene polymorphisms and haplotypes are associated with idiopathic male infertility in Iranian population., PMID:31228677
The differential neuroprotection of HSP70-hom gene single nucleotide polymorphisms: In vitro (neuronal hypoxic injury model) and in vivo (rat MCAO model) studies., PMID:31170438
In silico identification of epitopes present in human heat shock proteins (HSPs) overexpressed by tumour cells., PMID:31129262
Identification of aberrantly methylated differentially expressed genes in age-related macular degeneration., PMID:30946360
Angelica keiskei (Ashitaba) powder and its functional compound xanthoangelol prevent heat stress-induced impairment in sperm density and quality in mouse testes., PMID:30686791
Interactions of human chorionic gonadotropin with genotype and parity on fertility responses of lactating dairy cows., PMID:30447974
Association Studies of HSPA1A and HSPA1L Gene Polymorphisms With Schizophrenia., PMID:30342847
For research use only. Not for human or drug use.
