Catalog No.
YHE04101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly532-Ala787
Predicted molecular weight
31.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P33981
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dual specificity protein kinase TTK, MPS1L1, Phosphotyrosine picked threonine-protein kinase, TTK, PYT, MPS1
Factor H-related proteins and their associated disorders., PMID:40499620
Multi-omics and AI-driven immune subtyping to optimize neoantigen-based vaccines for colorectal cancer., PMID:40456769
Computer-aided drug discovery of a dual-target inhibitor for ovarian cancer: therapeutic intervention targeting CDK1/TTK signaling pathway and structural insights in the NCI-60., PMID:40446543
Isotope and archaeobotanical analysis reveal radical changes in mobility, diet and inequalities around 1500 BCE at the core of Europe., PMID:40394008
Cancer-associated fibroblast-derived fibulin-5 promotes epithelial-mesenchymal transition in diffuse-type gastric cancer via cAMP response element-binding protein pathway, showing poor prognosis., PMID:40369121
Radiation-Induced Synchronous Parathyroid Carcinoma and Papillary Thyroid Carcinoma: Clinical, Morphological, and Genetic Insights., PMID:40362680
Reduction in Gonad Development and Sperm Motility in Male Brown Planthopper Nilaparvata lugens via RNAi-Mediated Knockdown of tramtrack., PMID:40332247
Identification and validation of hub genes in uterine corpus endometrioid carcinoma: An observational study from TCGA and GEO., PMID:40324248
ATR-Infrared Spectroscopy and Acoustic Sensing in Characterization of Blood and Pancreatic Ductal Adenocarcinoma-Derived Extracellular Vesicles., PMID:40304913
Biophysical Profiling of Protein Corona on Red Blood Cell-Derived Extracellular Vesicles (REVs): Linear Dichroism and Microfluidic Resistive Pulse Sensing Separate Surface Clearing from Vesicle Disruption., PMID:40304912
Optimized Biotinylated Peptide Detection Method for Characterizing the Cell Surface Proteome., PMID:40304900
Gastrodin alleviates myocardial infarction by inhibiting inflammation, and apoptosis and promoting endothelial cell proliferation., PMID:40290804
Identification of key hub genes and potential therapeutic drugs for nasopharyngeal carcinoma: Insights into molecular mechanisms and treatment strategies., PMID:40286596
Integrin linked kinase and threonine tyrosine kinase modulate TCR signaling., PMID:40274929
TTK promotes mitophagy by regulating ULK1 phosphorylation and pre-mRNA splicing to inhibit mitochondrial apoptosis in bladder cancer., PMID:40269198
Determinants of site-selectivity in human ileal bile acid-binding protein by NMR dynamic analysis of a functionally-impaired mutant., PMID:40268173
Metastatic Prostatic Adenocarcinoma to the Penis with Diffuse P16 Expression: Recognizing a Diagnostic Pitfall., PMID:40254018
Defining the genome-wide mutagenic impact of APOBEC3 enzymes., PMID:40250950
Go for Gold: Development of a Scalable Synthesis of [1-(Ethoxycarbonyl)cyclopropyl] Triphenylphosphonium Tetrafluoroborate, a Key Reagent to Explore Covalent Monopolar Spindle 1 Inhibitors., PMID:40237105
Proximity-based activation of AURORA A by MPS1 potentiates error correction., PMID:40203828
Identifying ribonucleotide reductase subunit genes as potential lung adenocarcinomas biomarkers using integrated bioinformatics analysis., PMID:40191558
The sweet and the bitter sides of galectin-1 in immunity: its role in immune cell functions, apoptosis, and immunotherapies for cancer with a focus on T cells., PMID:40178639
Glycoproteomics Analysis of Triple Wild-Type Lung Adenocarcinoma Tissue Samples., PMID:40175289
AIUPred - Binding: Energy Embedding to Identify Disordered Binding Regions., PMID:40133781
Fluorescent tools for imaging class A G-protein coupled receptors., PMID:40113106
Prognostic Value of Centrosome Replication-Related Genes in Prostate Cancer Based on Transcriptomic and Mendelian Randomization., PMID:40099722
Integrative analysis of serum proteomics and transcriptomics in hepatitis C., PMID:40082995
Mps1 kinase functions in mitotic spindle assembly and error correction., PMID:40082122
Developing a gene expression classifier for breast cancer diagnosis., PMID:40080330
Exome sequencing identifies novel genes associated with cerebellar volume and microstructure., PMID:40025133
Uncovering the underlying mechanism of yuanhuacine against colorectal cancer by transcriptomics and experimental investigations., PMID:40023971
CENPF as a prognostic marker of glioma: unraveling the molecular mechanisms., PMID:40019588
Cancer-type OATP1B3-V1 is a functional plasma membrane transporter mediating increased uptake of chemotherapeutics in vitro and in vivo., PMID:39983930
Integrative analysis of T cell-mediated tumor killing-related genes reveals KIF11 as a novel therapeutic target in esophageal squamous cell carcinoma., PMID:39966857
Development and validation of a kinase-related gene signature as a novel diagnostic and prognostic model for prostate cancer., PMID:39965532
Threonine and tyrosine kinase promotes multiple myeloma progression by regulating regucalcin expression., PMID:39961467
JNK Inhibition Overcomes Resistance of Metastatic Tetraploid Cancer Cells to Irradiation-Induced Apoptosis., PMID:39940976
Decoding oral cancer: insights from miRNA expression profiles and their regulatory targets., PMID:39935706
Full-length inhibitor protein is the most effective to perturb human dUTPase activity., PMID:39924564
The hidden potential of solasonine: Targeting non-small cell lung cancer (NSCLC) metastasis through GATM and Smad2 pathways., PMID:39922150
Integrative Bioinformatics Analysis for Targeting Hub Genes in Hepatocellular Carcinoma Treatment., PMID:39911278
The impact of glucocorticoid receptor transactivation on context-dependent cell migration dynamics., PMID:39905197
High CDC20 levels increase sensitivity of cancer cells to MPS1 inhibitors., PMID:39838194
Multifactorial approach is needed to unravel the maturation phases of human neurons derived from induced pluripotent stem cells., PMID:39837910
Targeting TTK Inhibits Tumorigenesis of T-Cell Lymphoma Through Dephosphorylating p38α and Activating AMPK/mTOR Pathway., PMID:39836493
Simultaneous activation of different subtypes of dopamine receptors may lead to activation of homeostatic sleep regulatory mechanisms., PMID:39798808
Exploring the Conformational Space of MPS1 Kinase Using Metadynamics., PMID:39786318
Threonine and tyrosine kinase (TTK) mRNA and protein expression in breast cancer; prognostic significance in the neoadjuvant setting., PMID:39775836
Maternally activated connections of the ventral lateral septum reveal input from the posterior intralaminar thalamus., PMID:39775138
The miRNA-mRNA Regulatory Network in Human Hepatocellular Carcinoma by Transcriptomic Analysis From GEO., PMID:39764737