Catalog No.
YHE35901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser29-His277
Predicted molecular weight
30.80 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P42574
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Caspase-3, CPP-32, CPP32, CASP-3, SREBP cleavage activity 1, CASP3, Apopain, SCA-1, Cysteine protease CPP32, Protein Yama
Enzyme-sequential responsive core-satellite nanomedicine enables activatable near-infrared-II photoacoustic imaging-guided chemotherapy cascade-enhanced radiotherapy., PMID:40514655
Inhibitory effects of Levilactobacillus brevis IBRC-M10790 on apoptosis and inflammation induced by Clostridioides difficile culture supernatant in vitro., PMID:40514400
Estradiol inhibits endometrial injury by promoting the stability of the KLF15 protein and the recovery of mitochondrial function., PMID:40513792
miR-24-2 targets Akt and inhibits cell survival, EMT, and tumour growth in triple-negative breast cancer., PMID:40513147
Novel Perspective of Regulating P53/Bcl2/Caspase-3 via In vitro Targeted AFP Gene Knocks Out in HepG2 Cells Using CRISPR/Cas9 Editing Tool., PMID:40511828
AS-IV Attenuates Oxidative Stress-Induced Apoptosis in Zebrafish via Modulation of the AKT/NRF2/HO-1/Caspase-3 Signaling Axis., PMID:40509241
In Silico Exploration of Natural Antioxidants for Sepsis Drug Discovery., PMID:40509176
Mechanism Analysis of UCP2 During the Oxidative Stress Injury of Intestinal Porcine Epithelial Cell Line-J2., PMID:40509120
Pinobanksin ameliorates perfluorooctane sulfonate-evoked cardiotoxicity via targeting Nrf-2/Keap-1, oxidative damage and inflammation in Sprague Dawley rats., PMID:40505178
Therapeutic Role of l-Theanine in Mitigating Cognitive Dysfunction and Neuropathology in Scopolamine-Treated Mice., PMID:40504752
Polystyrene microplastics induces the injury of human corneal epithelial cells through ROS-mediated p53 pathway., PMID:40503930
Comparative analysis of mitochondrial and mesenchymal stem cell transplantation for angiogenesis and muscle regeneration., PMID:40503723
Mesenchymal Stem Cell Secretome Attenuates PrP106-126-Induced Neurotoxicity by Suppressing Neuroinflammation and Apoptosis and Enhances Cell Migration., PMID:40498027
Avenanthramide-C as Alzheimer's Disease-Modifying Therapy: Early and Sustained Intervention Prevents Disease Progression in Mouse Models., PMID:40498003
Air-Exposure- and Reoxygenation-Stimulated Expressions of Caspase-3 and Induction of Apoptosis in the Central Nervous System of the Crab Erimacrus isenbeckii., PMID:40498002
Oral Combined Probiotics Clostridium butyricum and Akkermansia muciniphila Inhibits the Progression of 4T1 Breast Cancer by Activating Bcl-2/Bax Pathway., PMID:40497373
Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation., PMID:40496861
Phosphatidylglucoside regulates apoptosis of human neutrophilic lineage cells., PMID:40496860
Roles of Mitochondrial Fusion and Division in Harmine Derivative H-2-168-Induced Neurotoxicity., PMID:40496271
Long non-coding RNA GAS5 promotes neuronal apoptosis in spinal cord injury via the miR-21/PTEN axis., PMID:40496261
Intranasal delivery of platelet cell membrane-cloaked Astragaloside IV loaded biomimetic nanoparticles for enhanced therapeutics in acute lung injury mice., PMID:40494449
Syringetin ameliorates thallium sulphate induced renal dysfunction via regulating Nrf2/Keap-1, TLR4/HMGB1/RAGE and NF-κB pathway., PMID:40494130
Exploration of the anticancer properties of Caffeic Acid in malignant mesothelioma cells., PMID:40493253
Investigating the impact of camel whey protein hydrolysate on cyp1a1 and keap1/nrf2 expression in hypoxic stress-affected liver tissue of Oreochromis niloticus., PMID:40493086
Activity-dependent synapse elimination requires caspase-3 activation., PMID:40492499
Neuroprotection unveiled: melatonin mitigates apoptotic pathways in traumatic brain injury., PMID:40492170
A β-glucosidase extracted from walnut (Juglans regia L.) green husk induces human hepatoma cell apoptosis via ROS-mediated p53 and NF-κB pathway., PMID:40492030
Erianin Protects Human Umbilical Vein Endothelial Cells From Oxidized Low-Density Lipoprotein-Induced Apoptosis and Oxidative Stress Through Activation of Nuclear Factor E2-Related Factor 2 Signaling., PMID:40490908
Anti-GBM effects of polyphenolic extract from Avicennia marina., PMID:40490234
Loss of ARNTL Enhances ER Stress and Apoptosis in CKD Through Disruption of NRF2 Signaling., PMID:40489010
Antagonism of 5-HT7 Receptors as a Promising Target for Gastric Cancer via Apoptotic Pathway., PMID:40488271
Involvement of IL-6/JAK/STAT3/SOCS3, SIRT1, and Cytoglobin Signaling in Diacerein Protective Effect against Intestinal Injury Induced by Methotrexate., PMID:40488252
Mechanisms Underlying the Therapeutic Effects of Brucea javanica in Cervical Cancer Treatment Based on Network Pharmacology and Molecular Docking., PMID:40487864
Mechanism of fumonisin B1 on growth performance and intestinal structural integrity of juvenile grass carp (Ctenopharyngodon idella)., PMID:40487097
A dual inhibitor of TrxR1 and XIAP induces pyroptosis in melanoma., PMID:40486906
Targeting apoptotic pathways in cancer: design, synthesis, and molecular docking studies of 1,3,5-trisubstituted-1H-pyrazole derivatives with Bcl-2 inhibition and DNA damage potential., PMID:40486169
Combined Oral Contraceptives Modulate Apoptosis via IL-11/PI3K/AKT Pathway in Rat With Premature Ovarian Insufficiency., PMID:40485524
Mechanism of AGT-Mediated Magnesium Ion Uptake in Age-Related Olfactory Dysfunction., PMID:40485519
Establishment of a Human Induced Pluripotent Stem Cell-Derived Cerebral Cortex Organoid Model for Neurotoxicity Assessment., PMID:40485229
Cytotoxicity induced by Aeromonas schubertii is orchestrated by a unique set of type III secretion system effectors., PMID:40484940
CYT997 Induces Apoptosis in Hypertrophic Scar Fibroblasts and Inhibits Scar Formation., PMID:40484336
Comprehensive two-dimensional primary hepatic stellate cell (HSC) membrane chromatography-based screening of anti-fibrotic components from Schisandra chinensis (Turcz.) Baill. and mechanistic insights into gomisin N against liver fibrosis., PMID:40484259
BASP1/HTRA2 axis, targeted by miR-7a-5p, exerted a pro-apoptosis role in myocardial ischemia/reperfusion injury., PMID:40484205
Tea polyphenols attenuate glufosinate-induced breast injury by reducing endoplasmic reticulum stress and autophagy., PMID:40482513
Neolitsea sericea attenuates oxidative stress-induced cell death in human neuroblastoma SH-SY5Y cells via MAPK and NF-κB pathway Inhibition., PMID:40481995
Silencing FGL1 promotes prostate cancer cell apoptosis and inhibits EMT progression., PMID:40481127
Gasdermin E deficiency limits inflammation and lung damage during influenza virus infection., PMID:40481027
Identification of potential therapeutic targets and epithelial cell signaling pathway for Helicobacter pylori infection using biosurfactants as a novel green antimicrobials: A network pharmacology approach., PMID:40480449
Mechanistic exploration of Dahuang Zhechong Pill against hepatic fibrosis via integrated serum pharmacochemistry, UHPLC-ESI-QTOF-MS/MS, network pharmacology, and molecular docking with cellular and zebrafish validation., PMID:40480395
Nuclear respiratory factor-1 promotes CFLAR transcription in H9C2 cardiomyocytes, protecting them against hypoxia-induced apoptosis., PMID:40478441
For research use only. Not for human or drug use.
