Catalog No.
YHE30701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile62-Lys380
Predicted molecular weight
38.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P41221
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein Wnt-5a, WNT5A
Quantification of Wnt3a, Wnt5a and Wnt16 Binding to Multiple Frizzleds Under Physiological Conditions Using NanoBit/BRET., PMID:40497984
RacGAP1 Plays an Oncogenic Role in Lung Adenocarcinoma by Regulating the Wnt/β-Catenin Pathway., PMID:40497948
Fermented black soldier fly larvae as a sustainable replacement for marine fish in Asian swamp eel diets., PMID:40453945
Hsa-miR-194-5p regulates TRAF6-mediated M1 macrophage apoptosis in recurrent spontaneous abortion., PMID:40418413
Identification of key genes and immune infiltration mechanisms in limb ischemia-reperfusion injury: a bioinformatics and experimental study., PMID:40416982
Porcupine inhibition enhances hypertrophic cartilage differentiation., PMID:40406350
Hypotaurine promotes glioma cell invasion by hypermethylating the Wnt5a promoter., PMID:40373156
Expression and Effects of FUS/Sfrp5/Wnt5 in Atherosclerosis Development., PMID:40340876
Venetoclax confers synthetic lethality to chidamide in preclinical models with transformed follicular lymphoma., PMID:40320542
Pilot study using a discrete mathematical approach for topological analysis and ssGSEA of gene expression in autosomal recessive polycystic kidney disease., PMID:40319097
Non-canonical Wnt signaling promotes epithelial fluidization in the repairing airway., PMID:40319020
UHRF1-mediated epigenetic reprogramming regulates glycolysis to promote progression of B-cell acute lymphoblastic leukemia., PMID:40301374
Wnt5a induces ROR1 dependent NF-κB activation to enhance MMP-9 expression and invasiveness in chronic lymphocytic leukemia., PMID:40295829
The Roxadustat (FG-4592) ameliorates tubulointerstitial fibrosis by promoting intact FGF23 cleavage., PMID:40281613
Hypoxia-induced Wnt5a-secreting fibroblasts promote colon cancer progression., PMID:40246836
Protein Kinase C Inhibition Overcomes Targeted Therapy Resistance in Cutaneous Melanoma., PMID:40243348
Serum and exosome WNT5A levels as biomarkers in non-small cell lung cancer., PMID:40223089
DjCapon Affects the Neural Regeneration and Light Sensitivity via NO and Wnt5a Signaling in Planarian Dugesia japonica., PMID:40220247
Association of Serum Secreted Frizzled-Related Protein 5 Levels With Coronary Artery Disease., PMID:40213711
Jiawei Erzhiwan Ameliorates Androgenetic Alopecia by Regulating the SIRT1/JNK/p38 MAPK Pathway., PMID:40190813
PPAR-gamma agonist pioglitazone improves endometrial receptivity, reverses endometrial barrier disruption and promotes ovarian function in thin endometrium rats via modulation PPAR-γ/Wnt5/β-catenin pathway., PMID:40186943
WNT5a export onto extracellular vesicles studied at single-molecule and single-vesicle resolution., PMID:40165582
Predicted functional consequences of WNT ligand mutations in colorectal cancer., PMID:40165370
TBG096 Ameliorates Memory Deficiency in AD Mouse Model via Promoting Neurogenesis and Regulation of Hsc70/HK2/PKM2/LAMP2A Signaling Pathway., PMID:40141445
Inhibition of stromal MAOA leading activation of WNT5A enhance prostate cancer immunotherapy by involving the transition of cancer-associated fibroblasts., PMID:40121032
Wnt5a augments intracellular free cholesterol levels and promotes castration resistance in prostate cancer., PMID:40102900
Gestational high-sucrose diet mediated vascular hyper-contractility in mesenteric arteries from offspring., PMID:40097492
Bisphenol S promotes clear cell renal cell carcinoma progression by modulating the WNT5A-dependent EMT pathway., PMID:40086502
Wnt5a in keratinocytes contributes to complex regional pain syndrome through the activation of NR2B and MMP9 in rats., PMID:40081928
TGF-β1 Mediates Novel-m0297-5p Targeting WNT5A to Participate in the Proliferation of Ovarian Granulosa Cells in Small-Tailed Han Sheep., PMID:40076587
Promoter Methylation of WIF1 is Involved in IL-17-Induced Chondrocyte Inflammatory Injury and Matrix Degradation via Promoting Wnt5a/MAPK-JNK Signaling., PMID:40072748
Fine-tuning of Wnt signaling by RNA surveillance factor Smg5 in the mouse craniofacial development., PMID:40071146
Single-cell and spatial transcriptome profiling reveal CTHRC1+ fibroblasts promote EMT through WNT5A signaling in colorectal cancer., PMID:40050872
Differential cellular origins of the extracellular matrix of tumor and normal tissues according to colorectal cancer subtypes., PMID:40032993
Gene expression associated with endocrine therapy resistance in estrogen receptor-positive breast cancer., PMID:40021703
Fatty acid uptake activates an AXL-CAV1-β-catenin axis to drive melanoma progression., PMID:40015991
The Noncanonical Wnt5a-Ca2+ Pathway Mediates Mitochondrial Dysfunction in the Progression of Diabetic Nephropathy via the Mitochondrial Calcium Uniporter., PMID:40008536
Syndromic and Non-Syndromic Primary Failure of Tooth Eruption: A Genetic Overview., PMID:40004475
Mechanisms of Resistance to Anti-PD-1 Immunotherapy in Melanoma and Strategies to Overcome It., PMID:40001572
Identification of Wnt-5a Receptors Important in Diabetic and Non-Diabetic Corneal Epithelial Wound Healing., PMID:39998459
Punicalagin ameliorates lipopolysaccharide-induced inflammatory response in dental pulp cells via inhibition of the NF-κB/Wnt5a-ROR2 pathway., PMID:39994845
Quercetin improves airway remodeling in COPD rats by suppressing phenotypic switch of ASMCs via inhibiting the Wnt5a/β-catenin pathway., PMID:39955824
Cancer-associated fibroblasts promote growth and dissemination of esophageal squamous cell carcinoma cells by secreting WNT family member 5A., PMID:39954174
Metformin reverses 5-FU chemoresistance by downregulating DKK1, WNT5A, and ABCB1 expressions in gastric cancer: An experimental and bioinformatic study., PMID:39954066
Altered Sertoli Cell Function Contributes to Spermatogenic Arrest in Dogs with Chronic Asymptomatic Orchitis., PMID:39940876
Injectable hydrogel microspheres promoting inflammation modulation and nucleus pulposus-like differentiation for intervertebral disc regeneration., PMID:39938720
Non-Canonical Wnt16 and microRNA-145 Mediate the Response of Human Bone Marrow Stromal Cells to Additively Manufactured Porous 3-Dimensional Biomimetic Titanium-Aluminum-Vanadium Constructs., PMID:39937002
Amyloid-β can activate JNK signalling via WNT5A-ROR2 to reduce synapse formation in Alzheimer's disease., PMID:39907042
Bone Marrow Mesenchymal Stem Cells-Derived Exosomes Inhibit Apoptosis of Pulmonary Microvascular Endothelial Cells in COPD Mice Through miR-30b/Wnt5a Pathway., PMID:39906523
Wnt signaling as a translational target in rheumatoid and psoriatic arthritis., PMID:39905450
For research use only. Not for human or drug use.
