Catalog No.
YHE29801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His177-Ala271
Predicted molecular weight
37.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P41181
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Aquaporin-2, AQP-CD, AQP2, Water channel protein for renal collecting duct, AQP-2, WCH-CD, Collecting duct water channel protein, Aquaporin-CD, ADH water channel
Nephrogenic Diabetes Insipidus Associated with Temozolomide Therapy in a Patient with Grade IV Astrocytoma., PMID:40502960
UPLC-Q-TOF-MS-Based Serum Metabolomics Explores the Mechanism of Pingwei Powder in Treating the Damp Retention in the Middle-Jiao Syndrome., PMID:40500971
Changes in Urinary Aquaporin 2 and Serum Sodium After Catheterization in Elderly Patients with Syndrome of Inappropriate Antidiuretic Hormone and Urinary Retention: A Preliminary Hospital-based Study in Yangon, Myanmar., PMID:40485652
ANKHD1 promotes pathogenic proliferation in Autosomal Dominant Polycystic Kidney Disease via the Cyclin D1/CDK4 pathway., PMID:40457431
Analysis of Kallikrein 6, Acetyl-α-Tubulin, and Aquaporin 1 and 2 Expression Patterns During Normal Human Nephrogenesis and in Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)., PMID:40428321
Renal G protein-coupled estrogen receptor 1 regulates the epithelial sodium channel promoting natriuresis to a greater extent in females., PMID:40402842
Tea drinking effectively improves symptoms of diabetes and prevents hepatorenal damage in mice., PMID:40356150
Tumour necrosis factor-alpha at the intersection of renal epithelial and immune cell function., PMID:40349332
Alteration of vasopressin-aquaporin system in hindlimb unloading mice., PMID:40303591
Uric acid reduces the expression of aquaporins in renal collecting ducts to increase urine output in hyperuricemia., PMID:40271210
Deletion of the prostaglandin EP4 receptor in the kidney tubule of mature mice alters kidney water handling only in males., PMID:40261807
CREB-family transcription factors and vasopressin-mediated regulation of Aqp2 gene transcription., PMID:40161632
Wnt-5a ameliorates sepsis-induced downregulation of renal AQP2 via the calcineurin signaling pathway., PMID:40140207
Lack of renal NHE1 exacerbates lithium-induced nephrogenic diabetes insipidus., PMID:40123120
Construction of arginine vasopressin receptor 2-deficient rats by the rGONAD method., PMID:40102322
Decreased Expression of Aquaporins as a Feature of Tubular Damage in Lupus Nephritis., PMID:40072108
Ozone exposure induced kidney damage in diabetic mice: The key role of lipid metabolism and water-electrolyte homeostasis., PMID:40037426
Clinical and Molecular Genetic Analyses of a Girl With Isolated Nephrogenic Diabetes Insipidus due to Contiguous Gene Deletion Involving AVPR2 and L1CAM., PMID:39992048
Loss of PRICKLE1 leads to abnormal endometrial epithelial architecture, decreased embryo implantation, and reduced fertility in mice., PMID:39917256
Various endurance training intensities improve GFR and Up-regulate AQP2/GSK3β in lithium-induced nephropathic rats., PMID:39915719
Trial to control the formation of endolymphatic hydrops from the viewpoint of the water homeostasis of the inner ear., PMID:39893739
Aquaporin-2 in the early stages of the adenine-induced chronic kidney disease model., PMID:39883648
Segment specific loss of NFAT5 function in the kidneys is sufficient to induce a global kidney injury like phenotype., PMID:39874047
Ribosomal s6 kinase is a mediator of aquaporin-2 S256 phosphorylation and membrane accumulation after EGFR inhibition with erlotinib., PMID:39823198
Investigation of the effects of silymarin and vitamin C on kidney damage and aquaporin-2 downregulation in lithium-induced nephrogenic diabetes insipidus in rats., PMID:39809261
Circadian rhythm disruptions exacerbate inner ear damage in a murine endolymphatic hydrops model., PMID:39781606
Hemodynamic Management with Vasopressin for Cardiovascular Surgery., PMID:39768943
Renal glomerular and tubular injury in the offspring of the preeclampsia-like syndrome., PMID:39762506
Arginine vasopressin and angiotensin II coregulate Aquaporin 2 expression in M-1 cells., PMID:39740402
Evaluation indicators of Traditional Chinese Medicine syndromes for gouty arthritis with damp heat accumulation and the effect of administering Tongfeng Qingxiao formula., PMID:39617706
Goreisan promotes diuresis by regulating the abundance of aquaporin 2 phosphorylated at serine 269 through calcium-sensing receptor activation., PMID:39609591
A semi-permeable insert culture model for the distal part of the nephron with human and mouse tubuloid epithelial cells., PMID:39566879
Tolvaptan and the role of kidney aquaporin-2 abundance in managing volume overload in patients with CKD., PMID:39449995
The biology of water homeostasis., PMID:39435642
Detection of renal tubular transporter proteins in canine urinary extracellular vesicles using liquid chromatography-tandem mass spectrometry., PMID:39432048
Focal Adhesion Kinase (FAK) inhibition induces membrane accumulation of aquaporin2 (AQP2) through endocytosis inhibition and actin depolymerization in renal epithelial cells., PMID:39416213
Disruption of mitochondrial electron transport impairs urinary concentration via AMPK-dependent suppression of aquaporin 2., PMID:39361429
Urinary Extracellular Vesicles for Non-Invasive Quantification of Principal Cell Damage in Kidney Transplant Recipients., PMID:39334890
Autosomal dominant nephrogenic diabetes insipidus in one family caused by a novel AQP2 mutation., PMID:39256939
The clinical manifestation and treatment of Meniere's Disease from the viewpoint of the water homeostasis of the inner ear., PMID:39244939
Osteogenic-Like Microenvironment of Renal Interstitium Induced by Osteomodulin Contributes to Randall's Plaque Formation., PMID:39225583
Transcriptomics-based analysis reveals hexafluoropropylene oxide trimer acid (HFPO-TA) induced kidney damage and lipid metabolism disorders in SD rats., PMID:39213752
Loss of PRICKLE1 leads to abnormal endometrial epithelial architecture, decreased embryo implantation, and reduced fertility in mice., PMID:39211179
Duloxetine-Induced Antidiuresis in Rats with Lithium-Induced Nephrogenic Diabetes Insipidus., PMID:39202754
Glucocorticoid-induced acute diuresis in rats in relation to the reduced renal expression of sodium-dependent cotransporter genes., PMID:39179330
Jinhong decoction ameliorates injury in septic mice without disrupting the equilibrium of gut microbiota., PMID:39154578
Identification of countercurrent tubule-vessel arrangements in the early development of mouse kidney based on immunohistochemistry and computer-assisted 3D visualization., PMID:39137214
Expression patterns and distribution of aquaporin water channels in cervix as a possible mechanism for cervical patency in bitches affected by pyometra., PMID:39067211
Structural Basis for the Interaction between the Ezrin FERM-Domain and Human Aquaporins., PMID:39062914
HL156A, an AMP-Activated Protein Kinase Activator, Inhibits Cyst Growth in Autosomal Dominant Polycystic Kidney Disease., PMID:39062520
For research use only. Not for human or drug use.
