Catalog No.
YHE21801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Leu199
Predicted molecular weight
24.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P37802
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIAA0120, Transgelin-2, TAGLN2, Epididymis tissue protein Li 7e, SM22-alpha homolog
TAGLN2 Exacerbates Acute Pancreatitis-Induced Liver Injury by Increasing Hepatocyte Pyroptosis via Kupffer Cells-Mediated Inflammatory Response., PMID:40472315
Species-specific sensitivity to intracerebroventricular streptozotocin in rats and mice highlights pathways and proteins relevant to Alzheimer's disease., PMID:40450637
Identification of multiomics and immune infiltration-associated biomarkers for early gastric cancer: a machine learning-based diagnostic model development study., PMID:40450287
TAGLN2-mediated Actin Cytoskeleton Stabilization Promotes Proliferation and Metastasis of Ovarian Carcinoma., PMID:40247723
A framework for studying multi-omic risk factors and their interplay: application to coronary artery disease., PMID:40236413
Comprehensive Proteomics and Machine Learning Analysis to Distinguish Follicular Adenoma and Follicular Thyroid Carcinoma from Indeterminate Thyroid Nodules., PMID:40205804
Multi-Omic Insight Into the Molecular Networks in the Pathogenesis of Coronary Artery Disease., PMID:40135555
Multifaceted role of transgelin isoforms in cancer hallmarks., PMID:40102702
Quantitative serum proteomic analysis for biomarker discovery in post-COVID-19 postural orthostatic tachycardia syndrome (PC-POTS) patients., PMID:40022872
Exploring novel drug targets for erectile dysfunction through plasma proteome with genome., PMID:39790564
Identification of the whole genome of alternative splicing and RNA-binding proteins involved in nintedanib-induced apoptosis in gastric cancer cells., PMID:39726754
A xenogenic-free culture medium for cell micro-patterning systems as cell-instructive biomaterials for potential clinical applications., PMID:39719129
Down-regulation of TAGLN2 associated with the development of preeclampsia by effecting the Rap1 signaling pathway., PMID:39602835
Transgelin 2 guards T cell lipid metabolism and antitumour function., PMID:39443795
TAGLN2 induces resistance signature ISGs by activating AKT-YBX1 signal with dual pathways and mediates the IFN-related DNA damage resistance in gastric cancer., PMID:39168971
Metformin Radiosensitizing Effect on Hypoxic Oral Squamous Cell Carcinoma Cells by GAPDH and TAGLN2., PMID:39160673
Unveiling the role of TAGLN2 in glioblastoma: From proneural-mesenchymal transition to Temozolomide resistance., PMID:38992489
Integrative multi-omics analysis unravels the host response landscape and reveals a serum protein panel for early prognosis prediction for ARDS., PMID:38956604
Oestrogen receptor positive breast cancer and its embedded mechanism: breast cancer resistance to conventional drugs and related therapies, a review., PMID:38889771
Thermostability-assisted limited proteolysis-coupled mass spectrometry for capturing drug target proteins and sites., PMID:38834267
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells., PMID:38744388
Unveiling Actin Cytoskeleton Role in Mediating Chikungunya-Associated Arthritis: An Integrative Proteome-Metabolome Study., PMID:38717066
Comparative proteomics analysis of samples from hepatic cystic echinococcosis patients using data-independent acquisition approach., PMID:38697285
Transgelin-2, a novel cancer stem cell-related biomarker, is a diagnostic and therapeutic target for biliary tract cancer., PMID:38509504
Circular STAG2 RNA Modulates Bladder Cancer Progression via miR-145-5p/TAGLN2 and Is Considered as a Biomarker for Recurrence., PMID:38473339
Potential Protein Signatures for Recurrence Prediction of Ischemic Stroke., PMID:38420847
Proteomic profiling of formalin-fixed paraffine-embedded tissue reveals key proteins related to lung dysfunction in idiopathic pulmonary fibrosis., PMID:38322285
TIMP1/CHI3L1 facilitates glioma progression and immunosuppression via NF-κB activation., PMID:38290591
Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function., PMID:38168227
Proteomic insights into the associations between obesity, lifestyle factors, and coronary artery disease., PMID:38049831
Genome-wide analysis revealed the dysregulation of RNA binding protein-correlated alternative splicing events in myocardial ischemia reperfusion injury., PMID:37858115
Spatial transcriptomics analysis of esophageal squamous precancerous lesions and their progression to esophageal cancer., PMID:37553345
An Integrated Analysis Identified TAGLN2 As an Oncogene Indicator Related to Prognosis and Immunity in Pan-Cancer., PMID:37476180
Single-cell RNA sequencing reveals the lineage of malignant epithelial cells and upregulation of TAGLN2 promotes peritoneal metastasis in gastric cancer., PMID:37247132
CircRNA ZKSCAN1 promotes lung adenocarcinoma progression by miR-185-5p/TAGLN2 axis., PMID:37105934
DNA Methylation of Window of Implantation Genes in Cervical Secretions Predicts Ongoing Pregnancy in Infertility Treatment., PMID:36982674
In silico analysis to identify novel ceRNA regulatory axes associated with gallbladder cancer., PMID:36873948
Proteomic and bioinformatic analysis of human endometrium from polycystic ovarian syndrome with and without insulin resistance., PMID:36750132
Serum Proteomics Combined with Metabolomics Analysis Explore the Molecular Biological Characteristics of Eruptive Syringoma., PMID:36636632
TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway., PMID:36547768
TAGLN2 promotes papillary thyroid carcinoma invasion via the Rap1/PI3K/AKT axis., PMID:36222755
Lysine-40 succinylation of TAGLN2 induces glioma angiogenesis and tumor growth through regulating TMSB4X., PMID:36131066
Chrysin-Induced G Protein-Coupled Estrogen Receptor Activation Suppresses Pancreatic Cancer., PMID:36077069
MOBT Alleviates Pulmonary Fibrosis through an lncITPF-hnRNP-l-Complex-Mediated Signaling Pathway., PMID:36014574
Salvianolic acid A (Sal A) suppresses malignant progression of glioma and enhances temozolomide (TMZ) sensitivity via repressing transgelin-2 (TAGLN2) mediated phosphatidylinositol-3-kinase (PI3K) / protein kinase B (Akt) pathway., PMID:35505656
Comparative proteomics identify HSP90A, STIP1 and TAGLN-2 in serum extracellular vesicles as potential circulating biomarkers for human adenomyosis., PMID:35495589
Mechanisms of Transgelin-2 in Tumorigenesis., PMID:35219353
Transgelin-2 in Multiple Myeloma: A New Marker of Renal Impairment?, PMID:35011306
[Effect and mechanism of circular RNA BICD2 on the biological behavior of oral squamous cell carcinoma cells]., PMID:34763405
Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration., PMID:34553339
For research use only. Not for human or drug use.
