Catalog No.
YHE21201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp230-Tyr505
Predicted molecular weight
33.84 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P37231
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NR1C3, Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma, PPAR-gamma, PPARG
RACK1 promotes the development and function of alveolar macrophages through directly binding to and stabilizing PPARγ., PMID:40512793
Comprehensive bioinformatics analysis and experimental verification identify mitochondrial gene Dgat2 as a novel therapeutic biomarker for myocardial ischemia-reperfusion., PMID:40510478
Uncovering the pharmacological mechanisms of bifendate against chronic kidney disease using computational pharmacology and experimental verification., PMID:40505415
Protein carbamylation in atherosclerotic plaques correlates with uremia and disease progression, localizing predominantly to foam cells., PMID:40503238
A multi-omics exploration of PPARG activation in colon cancer: kinases featuring a PPRE sequence within regulatory regions., PMID:40500799
Low-Abundance Serum Protein Biomarker Candidates for HCC in Patients with Liver Cirrhosis., PMID:40490917
α-Asarone Promotes Tendon-Bone Healing Through Regulating Dmp1 Transcription via Targeting Transcription Factor PPARG in BMSCs., PMID:40488746
Metabolomics combined with network pharmacology reveals the anti-hepatoma effects of terpenoids from Polygonatum kingianum var. grandifolium and Polygonatum sibiricum Redouté as well as differences in their terpenoid metabolites., PMID:40474061
Integrated metabolomics and network pharmacology to explore the mechanism of Huzhang Erjin Decoction against ANIT-induced cholestatic hepatitis., PMID:40466881
Analyzing the potential targets and mechanism of per- and polyfluoroalkyl substances (PFAS) on breast cancer by integrating network toxicology, single-cell sequencing, spatial transcriptomics, and molecular simulation., PMID:40465018
Integrative multi-omics study identifies sex-specific molecular signatures and immune modulation in bladder cancer., PMID:40458476
MACanalyzeR scRNAseq analysis tool reveals PPARγHIGH/GDF15HIGH lipid-associated macrophages facilitate thermogenic expansion in BAT., PMID:40450001
Systematic Exploration of Potential Toxicity Targets and Molecular Mechanisms of Emerging Short-Chain PFAS Substitutes: PFBA- and PFBS-Induced Hepatocellular Carcinoma Based on Toxicity Network Analysis, Machine Learning, and Biomimetic Calculations., PMID:40448290
Computational investigation and experimental validation of the molecular mechanism of Solanecio mannii aqueous roots extract against cervical cancer., PMID:40446016
RT-qPCR Quantification of Adipogenic Marker Genes (PPARg, C/EBPa, FABP4, and CD36)., PMID:40445279
Protective effect of phosphoenolpyruvate carboxykinase 1 on inflammation and fibrotic progression of IgA nephropathy., PMID:40442892
Age-related stress gene expression in neonatal sepsis involves regulatory networks and immune cell infiltration., PMID:40442112
Single-cell RNAseq of Angiotensin II-induced abdominal aortic tissue identifies aneurysm-associated cell clusters in C57BL/6J mice., PMID:40440080
Therapeutic role of Crateva religiosa in diabetic nephropathy: Insights into key signaling pathways., PMID:40435181
Carboxylesterase 1 regulates peroxisome proliferator-activated receptor gamma to inhibit the growth and metastasis of breast cancer cells., PMID:40418235
Generation of Human Monocyte-Derived Immunogenic Dendritic Cells via mTORC1 and PPARγ Inhibition., PMID:40402460
Perivascular adipose tissue dysfunction contributes to thoracic aortic aneurysm development., PMID:40399937
The working mechanism of biomarkers related to sumoylation modification in coronary artery disease., PMID:40379803
Longitudinal expression profiles of key markers during stages of adipogenic differentiation of 3T3-L1 cells using the PPARG agonist rosiglitazone., PMID:40378617
Exploring the pharmacokinetic, toxicity and anti-arthritic activity of bioactive polyphenols to mitigate the HIF-regulated angiogenic-pannus growth in rheumatoid arthritis., PMID:40373592
ATF1 and miR-27b-3p drive intervertebral disc degeneration through the PPARG/NF-κB signaling axis., PMID:40369110
Exploring the therapeutic potential and in vitro validation of baicalin for the treatment of triple-negative breast cancer., PMID:40356970
LncRNA SCARNA8 promotes atherosclerotic plaque instability by inhibiting macrophage efferocytosis., PMID:40356342
Mechanistic insights into the anticancer, anti-inflammatory, and antioxidant effects of yellowfin tuna collagen peptides using network pharmacology., PMID:40352189
[UPLC-Q-TOF-MS combined with network pharmacology reveals effect and mechanism of Gentianella turkestanorum total extract in ameliorating non-alcoholic steatohepatitis]., PMID:40350886
[Identification of blood-entering components of Anshen Dropping Pills based on UPLC-Q-TOF-MS/MS combined with network pharmacology and evaluation of their anti-insomnia effects and mechanisms]., PMID:40350885
Palmitic acid and lipopolysaccharide induce macrophage TNFα secretion, suppressing browning regulators and mitochondrial respiration in adipocytes., PMID:40348028
Inhibitory effects of kukoamine B on adipogenesis and lipid accumulation in vitro and obesity in vivo., PMID:40347845
Disruption of PPARG Activity and CPT1A Regulation by Bisphenol A: Implications for Hepatic Lipid Metabolism., PMID:40346756
The anti-diabetic PPARγ agonist Pioglitazone inhibits cell proliferation and induces metabolic reprogramming in prostate cancer., PMID:40320521
Exploration of ACE inhibitory peptides from sea cucumber viscera with DPP-IV inhibitory activity: Virtual screening, characterization, and potential mechanism investigation., PMID:40318712
Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 Drives Subchondral Bone Damage in Temporomandibular Joint Osteoarthritis through Peroxisome Proliferator-Activated Receptor γ/C-FOS-Regulated Dual Pathways: Nuclear Factor of Activated T Cells 1 Signaling and Autophagy-Related 16-Like 2-Mediated Autophagy., PMID:40316216
Ganoderic acid A: an in-depth review of pharmacological effects and molecular docking analysis., PMID:40316150
TAMing immunity through an unexpected source., PMID:40315841
PPARγ promotes urothelial remodeling during urinary tract obstruction., PMID:40307567
PPARG Activation of Fatty Acid Metabolism Drives Resistance to Anti-HER2 Therapies in HER2-Positive Breast Cancer., PMID:40303293
USP22 enhances atherosclerotic plaque stability and macrophage efferocytosis by stabilizing PPARγ., PMID:40301680
Transcriptome-based analysis reveals relationship between duck eggshell color and eggshell strength., PMID:40295915
Dyslipidemia and aging: the non-linear association between atherogenic index of plasma (AIP) and aging acceleration., PMID:40281579
Secoiridoid-enriched extra virgin olive oil extracts enhance mitochondrial activity and antioxidant response in colorectal cancer cells: The role of Oleacein and Oleocanthal in PPARγ interaction., PMID:40280312
Hemp seed protein exerts its hypoglycemic and hypolipidemic effects through degradation into short peptides., PMID:40279904
A signpost to guide the key therapeutic components of Aralia continentalis Kitag roots in treating T2DM-derived heart attack, and diabetic nephropathy via systems biology concept., PMID:40274257
Protective effects of Salidroside against ferroptosis through PPARG-dependent mechanism in diabetes-related cognitive impairment., PMID:40262718
Uncovering mechanism of hepatotoxicity diseases caused by tetrahydrocannabinol based on novel network toxicology and experimental verification., PMID:40258948
The role of cytokine licensing in shaping the therapeutic potential of wharton's jelly MSCs: metabolic shift towards immunomodulation at the expense of differentiation., PMID:40254602
For research use only. Not for human or drug use.
