Catalog No.
YHE21101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala186-Lys432
Predicted molecular weight
27.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P37198
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Nuclear pore glycoprotein p62, Nucleoporin Nup62, 62 kDa nucleoporin, NUP62
NUP62 alleviates senescence and promotes the stemness of human dental pulp stem cells via NSD2-dependent epigenetic reprogramming., PMID:40246825
Exploring NUP62's role in cancer progression, tumor immunity, and treatment response: insights from multi-omics analysis., PMID:40098960
Nuclear transport protein suppresses Tau neurodegeneration., PMID:39843141
Coronavirus nucleocapsid protein enhances the binding of p-PKCα to RACK1: Implications for inhibition of nucleocytoplasmic trafficking and suppression of the innate immune response., PMID:39602452
Channel width modulates the permeability of DNA origami-based nuclear pore mimics., PMID:39536094
Channel width modulates the permeability of DNA origami based nuclear pore mimics., PMID:38766144
Monitoring HIV-1 Nuclear Import Kinetics Using a Chemically Induced Nuclear Pore Blockade Assay., PMID:38743226
A three-gene expression score for predicting clinical benefit to anti-PD-1 blockade in advanced renal cell carcinoma., PMID:38660294
Exploring the Importance of Differential Expression of Autophagy Markers in Term Placentas from Late-Onset Preeclamptic Pregnancies., PMID:38396708
Murine leukemia virus infection of non-dividing dendritic cells is dependent on nucleoporins., PMID:38215165
Cyclin B Export to the Cytoplasm via the Nup62 Subcomplex and Subsequent Rapid Nuclear Import Are Required for the Initiation of Drosophila Male Meiosis., PMID:37998346
CX3CR1 regulates the development of renal interstitial fibrosis through macrophage polarization., PMID:37724398
p62 and NBR1 functions are dispensable for aggrephagy in mouse ESCs and ESC-derived neurons., PMID:37620146
Analysis of Bub3 and Nup75 in the Drosophila male germline lineage., PMID:37286104
Regulation of FLC nuclear import by coordinated action of the NUP62-subcomplex and importin β SAD2., PMID:37278318
Indel driven rapid evolution of core nuclear pore protein gene promoters., PMID:37198214
"From molecular to clinic": The pivotal role of CDC42 in pathophysiology of human papilloma virus related cancers and a correlated sensitivity of afatinib., PMID:36936942
RNA-seq reveals Nup62 as a potential regulator for cell division after traumatic brain injury in mice hippocampus., PMID:36908815
Overexpressed Nup88 stabilized through interaction with Nup62 promotes NF-κB dependent pathways in cancer., PMID:36845732
Modeling HIV-1 nuclear entry with nucleoporin-gated DNA-origami channels., PMID:36807645
Interactions between FUS and the C-terminal Domain of Nup62 are Sufficient for their Co-phase Separation into Amorphous Assemblies., PMID:36690069
Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy., PMID:36482422
Recessive NUP54 Variants Underlie Early-Onset Dystonia with Striatal Lesions., PMID:36333996
Amorfrutin B Protects Mouse Brain Neurons from Hypoxia/Ischemia by Inhibiting Apoptosis and Autophagy Processes Through Gene Methylation- and miRNA-Dependent Regulation., PMID:36324052
Insights into the role of Nup62 and Nup93 in assembling cytoplasmic ring and central transport channel of the nuclear pore complex., PMID:36222862
Acetylation of Nup62 by TIP60 ensures accurate chromosome segregation in mitosis., PMID:36190325
Mislocalization of Nup62 Contributes to TDP-43 Proteinopathy in ALS/FTLD., PMID:36001801
NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility., PMID:35697676
Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold., PMID:35679401
Cryo-EM structure of the inner ring from the Xenopus laevis nuclear pore complex., PMID:35301439
Partial Disassembly of the Nuclear Pore Complex Proteins during Semi-Closed Mitosis in Dictyostelium discoideum., PMID:35159217
NSP9 of SARS-CoV-2 attenuates nuclear transport by hampering nucleoporin 62 dynamics and functions in host cells., PMID:34844119
A Novel Variation in the Mitochondrial Complex I Assembly Factor NDUFAF5 Causes Isolated Bilateral Striatal Necrosis in Childhood., PMID:34177781
Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology., PMID:34060470
O-GlcNAc Engineering on a Target Protein in Cells with Nanobody-OGT and Nanobody-splitOGA., PMID:33950562
Nuclear Pore Complex 62 Promotes Metastasis of Gastric Cancer by Regulating Wnt/β-Catenin and TGF-β Signaling Pathways., PMID:33822519
A nuclear export sequence promotes CRM1-dependent targeting of the nucleoporin Nup214 to the nuclear pore complex., PMID:33589493
Conformation of the nuclear pore in living cells is modulated by transport state., PMID:33346731
Molecular and structural analysis of central transport channel in complex with Nup93 of nuclear pore complex., PMID:33085133
Genomic identification and expression analysis of nuclear pore proteins in Malus domestica., PMID:33060661
NUP62 is required for the maintenance of the spindle assembly checkpoint and chromosomal stability., PMID:32905854
Autophagy-related neurotoxicity is mediated via AHR and CAR in mouse neurons exposed to DDE., PMID:32721735
The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways., PMID:32620905
Changes in Nup62 content affect contact-induced differentiation of cultured myoblasts., PMID:32554220
Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus., PMID:32483230
Nucleocytoplasmic shuttling of the glucocorticoid receptor is influenced by tetratricopeptide repeat-containing proteins., PMID:32467326
The Nuclear Pore Complex: A Target for NS3 Protease of Dengue and Zika Viruses., PMID:32466480
Engineering a Proximity-Directed O-GlcNAc Transferase for Selective Protein O-GlcNAcylation in Cells., PMID:32119511
Nuclear Export of Cyclin B Mediated by the Nup62 Complex Is Required for Meiotic Initiation in Drosophila Males., PMID:31979075
Interactions between non-structured domains of FG- and non-FG-nucleoporins coordinate the ordered assembly of the nuclear pore complex in mitosis., PMID:31914646
For research use only. Not for human or drug use.
