Catalog No.
YHD80101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu778-Ala986
Predicted molecular weight
26.39 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P28715
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ERCC5, DNA excision repair protein ERCC-5, ERCM2, XPGC, Xeroderma pigmentosum group G-complementing protein, XPG, DNA repair protein complementing XP-G cells
Distribution of genetic polymorphisms of nucleotide excision repair genes and risk of gastrointestinal cancer: Findings from a case-control study., PMID:40377615
Genetic signatures of ERCC1 and ERCC2 expression, along with SNPs variants, unveil favorable prognosis in SCLC patients undergoing platinum-based chemotherapy., PMID:39735668
Genetic variations in NER pathway gene polymorphisms and Wilms tumor risk: A six-center case-control study in East China., PMID:39415460
Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair., PMID:39353945
Persistent TFIIH binding to non-excised DNA damage causes cell and developmental failure., PMID:38664429
Genetic Polymorphisms of XPC, XPD, XPG Genes and their Association with Radiotherapy Induced Toxicity among Head and Neck Cancer Patients: A Hospital Based Study from Maharashtra., PMID:38285784
R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response., PMID:36544021
Elucidation of Increased Cervical Cancer Risk Due to Polymorphisms in XRCC1 (R399Q and R194W), ERCC5 (D1104H), and NQO1 (P187S)., PMID:36195778
ERCC5, HES6 and RORA are potential diagnostic markers of coronary artery disease., PMID:35934844
Variants of ERCC5 and the outcome of platinum-based regimens in non-small cell lung cancer: a prospective cohort study., PMID:35852645
A stable XPG protein is required for proper ribosome biogenesis: Insights on the phenotype of combinate Xeroderma Pigmentosum/Cockayne Syndrome patients., PMID:35802638
Association of nonsynonymous SNPs of nucleotide excision repair genes ERCC4 rs1800067 (G/A) and ERCC5 rs17655 (G/C) as predisposing risk factors for gallbladder cancer., PMID:35780063
Effects of ERCC5 rs751402 Polymorphism on Oxidative Stress and the Impact of Curcumin on Catalase Activity in Breast Carcinogenesis., PMID:35763649
XPG: a multitasking genome caretaker., PMID:35230528
Relationship of ERCC5 genetic polymorphisms with metastasis and recurrence of gastric cancer., PMID:34909875
Upregulation of mNEIL3 in Ogg1-null cells is a potential backup mechanism for 8-oxoG repair., PMID:34644377
Transcriptional Stress Induces Chromatin Relocation of the Nucleotide Excision Repair Factor XPG., PMID:34205418
The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing., PMID:34039990
Modulation of DNA damage by XPF, XPG and ERCC1 gene polymorphisms in pesticide-exposed agricultural workers of Punjab, North-West India., PMID:33551103
Role of ERCC5 polymorphisms in non‑small cell lung cancer risk and responsiveness/toxicity to cisplatin‑based chemotherapy in the Chinese population., PMID:33469680
XPG gene polymorphisms and glioma susceptibility: a two-centre case-control study., PMID:33393424
COFS type 3 in an Indian family with antenatally detected arthrogryposis., PMID:33219753
The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair., PMID:32821917
Association of ERCC5 Genetic Polymorphisms With Cirrhosis and Liver Cancer., PMID:32812509
Association of XPG rs17655G>C and XPF rs1799801T>C Polymorphisms with Susceptibility to Cutaneous Malignant Melanoma: Evidence from a Case-Control Study, Systematic Review and Meta-Analysis., PMID:32683874
Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations., PMID:32522879
Prenatal diagnosis of cerebro-oculo-facio-skeletal syndrome: Report of three fetuses and review of the literature., PMID:32052936
Nucleotide excision repair pathway gene polymorphisms are associated with risk and prognosis of colorectal cancer., PMID:31988591
Exploring new potential role of DDB2 by host cell reactivation assay in human tumorigenic cells., PMID:31664956
DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering., PMID:31653834
Genetic variants of nucleotide excision repair pathway and outcomes of induction therapy in acute myeloid leukemia., PMID:31647372
Association between nucleotide excision repair gene polymorphism and colorectal cancer risk., PMID:31568607
Association of XPG rs2094258 polymorphism with gastric cancer prognosis., PMID:31558863
Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks., PMID:31533039
Novel analytical methods to interpret large sequencing data from small sample sizes., PMID:31470908
Risk Modulation of Oral Pre Cancer and Cancer with Polymorphisms in XPD and XPG Genes in North Indian Population., PMID:31450912
Thyroid Cancer: The Quest for Genetic Susceptibility Involving DNA Repair Genes., PMID:31374908
Structural basis of TFIIH activation for nucleotide excision repair., PMID:31253769
Heterogeneity and overlaps in nucleotide excision repair disorders., PMID:30919937
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells., PMID:30808711
Association of BER and NER pathway polymorphism haplotypes and micronucleus frequencies with global DNA methylation in benzene-exposed workers of China: Effects of DNA repair genes polymorphisms on genetic damage., PMID:30744808
Are XPD and XPG gene variants related to the mechanism of oral squamous cell carcinoma?, PMID:30672443
XPG polymorphisms and their association with lung cancer susceptibility, overall survival and response in North Indian patients treated with platinum-based doublet chemotherapy., PMID:30522358
Meta-analysis of the relationship between excision repair cross-complementing Group 5 rs17655 gene polymorphism and head and neck cancer susceptibility., PMID:30539843
The relationship between DNA repair genes (XPA, XPF, XPG) polymorphism and the risk of preeclampsia in Chinese Han Women., PMID:30527102
Relationship between the Asp1104His polymorphism of the nucleotide excision repair gene ERCC5 and treatment sensitivity to oxaliplatin in patients with advanced colorectal cancer in China., PMID:30517302
An insight into clinical outcome of XPG polymorphisms in breast cancer., PMID:30255276
Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair., PMID:30245011
XPG rs873601 G>A contributes to uterine leiomyoma susceptibility in a Southern Chinese population., PMID:30139812
For research use only. Not for human or drug use.
