Catalog No.
YHD76801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Ala239
Predicted molecular weight
27.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P28072
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Macropain delta chain, Proteasome subunit beta type-6, Proteasome subunit Y, Y, Proteasome delta chain, Multicatalytic endopeptidase complex delta chain, PSMB6, LMPY
Deficiency of psmb6 suppresses proteasome activity and promotes apoptosis in larval zebrafish brain., PMID:40048760
Limiting cap-dependent translation increases 20S proteasomal degradation and protects the proteomic integrity in autophagy-deficient skeletal muscle., PMID:39878121
Transcriptomic Profiling Reveals 17β-Estradiol Treatment Represses Ubiquitin-Proteasomal Mediators in Skeletal Muscle of Ovariectomized Mice., PMID:39865408
Corrigendum: Immune regulation and prognostic prediction model establishment and validation of PSMB6 in lung adenocarcinoma., PMID:39698469
Immune regulation and prognostic prediction model establishment and validation of PSMB6 in lung adenocarcinoma., PMID:39507618
Nuclear factor erythroid 2-related factor 1 regulates the expression of proteasomal genes in ketotic cows and protects mammary cells against free fatty acid-induced endoplasmic reticulum stress., PMID:39343197
Diminished expression of the ubiquitin-proteasome system in early treatment-naïve patients with rheumatoid arthritis and concomitant type 2 diabetes may be linked to IL-1 pathway hyper-activity; results from PEAC cohort., PMID:39342401
[Establishment of a stable THP-1 cell line expressing PSMB9-eGFP-His protein and detection of immunoproteasome activity]., PMID:39044591
Role of the ubiquitin-proteasome system in the sarcopenic-like phenotype induced by CCL5/RANTES., PMID:38357936
Hepatocyte-specific Wtap deficiency promotes hepatocellular carcinoma by activating GRB2-ERK depending on downregulation of proteasome-related genes., PMID:37777158
Downregulation of hepatic METTL3 contributes to APAP-induced liver injury in mice., PMID:37456679
Method of Monitoring 26S Proteasome in Cells Revealed the Crucial Role of PSMA3 C-Terminus in 26S Integrity., PMID:37371572
Interplay between proteasome function and inflammatory responses in e-cig vapor condensate-challenged lung epithelial cells., PMID:37344694
The STAT3 inhibitor stattic overcome bortezomib-resistance in multiple myeloma via decreasing PSMB6., PMID:37207970
Breast cancer cell secretome analysis to decipher miRNA regulating the tumor microenvironment and discover potential biomarkers., PMID:37128318
Identification and Verification of Potential Biomarkers in Renal Ischemia-Reperfusion Injury by Integrated Bioinformatic Analysis., PMID:36778059
Potential Cytoprotective and Regulatory Effects of Ergothioneine on Gene Expression of Proteins Involved in Erythroid Adaptation Mechanisms and Redox Pathways in K562 Cells., PMID:36553634
Oncolytic avian reovirus σA-modulated fatty acid metabolism through the PSMB6/Akt/SREBP1/acetyl-CoA carboxylase pathway to increase energy production for virus replication., PMID:35998542
Evaluation of Immunoproteasome-Specific Proteolytic Activity Using Fluorogenic Peptide Substrates., PMID:35799704
A Hypoxia-Associated Prognostic Gene Signature Risk Model and Prognosis Predictors in Gliomas., PMID:34868920
Identification and Validation of a Proliferation-Associated Score Model Predicting Survival in Lung Adenocarcinomas., PMID:34721732
Metabolic Processes are Potential Biological Processes Distinguishing Nonischemic Dilated Cardiomyopathy from Ischemic Cardiomyopathy: A Clue from Serum Proteomics., PMID:34557019
Transcriptome Analysis Reveals Possible Immunomodulatory Activity Mechanism of Chlorella sp. Exopolysaccharides on RAW264.7 Macrophages., PMID:33919822
CRISPR Co-Editing Strategy for Scarless Homology-Directed Genome Editing., PMID:33916763
The role of circadian rhythm in the regulation of cellular protein profiles in the brain., PMID:33356029
Proteomic Profiling of Serum Exosomes From Patients With Metastatic Gastric Cancer., PMID:32754443
The IFN-γ-induced immunoproteasome is suppressed in highly pathogenic porcine reproductive and respiratory syndrome virus-infected alveolar macrophages., PMID:32535163
N-myc downstream-regulated gene 2 deficiency aggravates memory impairment in Alzheimer's disease., PMID:31778735
Identification of Proteins Differentially Expressed by Adipose-derived Mesenchymal Stem Cells Isolated from Immunodeficient Mice., PMID:31151297
Identification and Validation of Novel Reference Genes in Acute Lymphoblastic Leukemia for Droplet Digital PCR., PMID:31108950
CHAF1B knockdown blocks migration in a hepatocellular carcinoma model., PMID:29767268
The Favored Mechanism for Coping with Acute Cold Stress: Upregulation of miR-210 in Rats., PMID:29723850
Impaired Proteasomal Function in Human Osteoarthritic Chondrocytes Can Contribute to Decreased Levels of SOX9 and Aggrecan., PMID:29457374
Avian reovirus p17 and σA act cooperatively to downregulate Akt by suppressing mTORC2 and CDK2/cyclin A2 and upregulating proteasome PSMB6., PMID:28701787
Expression of immunoproteasome genes is regulated by cell-intrinsic and -extrinsic factors in human cancers., PMID:27659694
The ubiquitin-proteasome system and chromosome 17 in cerebellar granule cells and medulloblastoma subgroups., PMID:27592301
Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution., PMID:27493218
Inhibition on Proteasome β1 Subunit Might Contribute to the Anti-Cancer Effects of Fangchinoline in Human Prostate Cancer Cells., PMID:26512898
Modulation of host ubiquitin system genes in human endometrial cell line infected with Mycobacterium tuberculosis., PMID:26403675
Characterization of the Interaction between the Matrix Protein of Vesicular Stomatitis Virus and the Immunoproteasome Subunit LMP2., PMID:26311888
Identification of collaborative activities with oxidative phosphorylation in bipolar disorder., PMID:26124562
Proteomics analysis of malignant and benign prostate tissue by 2D DIGE/MS reveals new insights into proteins involved in prostate cancer., PMID:26074449
Comparative proteomic analysis of anti-cancer mechanism by periplocin treatment in lung cancer cells., PMID:24685647
Proteomic analysis reveals that proteasome subunit beta 6 is involved in hypoxia-induced pulmonary vascular remodeling in rats., PMID:23844134
Identification of proteasome subunit beta type 6 (PSMB6) associated with deltamethrin resistance in mosquitoes by proteomic and bioassay analyses., PMID:23762443
Sequence analysis of β-subunit genes of the 20S proteasome in patients with relapsed multiple myeloma treated with bortezomib or dexamethasone., PMID:23018640
Involvement of the Nrf2-proteasome pathway in the endoplasmic reticulum stress response in pancreatic β-cells., PMID:22959925
Molecular characterization, expression analysis and association study with immune traits of porcine PSMB6 gene., PMID:21604174
Loss of nuclear factor E2-related factor 1 in the brain leads to dysregulation of proteasome gene expression and neurodegeneration., PMID:21536885
Early-age-related changes in proteostasis augment immunopathogenesis of sepsis and acute lung injury., PMID:21085581
For research use only. Not for human or drug use.
