Catalog No.
YHD11601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser101-Lys187
Predicted molecular weight
12.43 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P15514
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AREG, CRDGF, SDGF, Colorectum cell-derived growth factor, AREGB, Amphiregulin, AR
CYR61 and CTGF mediate the stimulatory effect of amphiregulin on COX-2 expression in human granulosa-lutein cells., PMID:40506006
FOXP3+ Macrophage-Derived Amphiregulin Promotes White Matter Repair of Experimental Autoimmune Encephalomyelitis., PMID:40497405
AREG+ regulatory T cells mediating myocardial repair and neovascularization after myocardial infarction., PMID:40495143
Changes in Gene Transcription in Cumulus Cells from Women of Advanced Maternal Age under the Influence of Extracellular Vesicles from Follicular Fluid of Young Donors., PMID:40448879
17β-Estradiol Promotes Tumorigenicity Through an Autocrine AREG/EGFR Loop in ER-α-Positive Breast Cancer Cells., PMID:40422206
GDF15 suppresses abdominal aortic aneurysm by upregulating AREG expression to adjust macrophage polarization., PMID:40414071
Hepatic stellate cell-specific Kcnma1 deletion mitigates metabolic dysfunction-associated steatotic liver disease progression via upregulating Amphiregulin secretion., PMID:40348016
Interactions between cancer cells and tumor-associated macrophages in tumor microenvironment., PMID:40345263
Amphiregulin Mediates Epithelial Cell-Eosinophil Interactions and Amplifies Inflammation in Chronic Rhinosinusitis With Nasal Polyps., PMID:40317745
LPS-induced extracellular AREG triggers macrophage pyroptosis through the EGFR/TLR4 signaling pathway., PMID:40292295
E2F expression profiling-based subtypes in head and neck squamous cell carcinoma: clinical relevance, prognostic implications, and personalized therapy., PMID:40275315
BMAL1-HIF2A heterodimer modulates circadian variations of myocardial injury., PMID:40269168
Treg and intestinal myofibroblasts-derived Amphiregulin induced by TGF-β mediates intestinal fibrosis in Crohn's disease., PMID:40247299
Enhanced renal ischemia/reperfusion injury repair potential of exosomes derived from B7-H1high mesenchymal stem cells., PMID:40242472
ILC2 instructs neural stem and progenitor cells to potentiate neurorepair after stroke., PMID:40233748
Calcium/Calmodulin-Dependent Protein Kinase II β Regulates Autophagy Dependent Ferroptosis of Neurons after Cerebral Ischemic Injury by Activating the AREG/JUN/ELAVL1 Pathway., PMID:40220216
Cancer-associated fibroblasts derived amphiregulin promotes HNSCC progression and drug resistance of EGFR inhibitor., PMID:40216150
Auricularia auricula polysaccharides alleviate experimental silicosis by targeting EGFR through the "gut-lung axis"., PMID:40147652
Characterizing serotonin expression throughout bovine mammary gland developmental stages and its relationship with 17β-estradiol at puberty., PMID:40131888
EGFR-mediated local invasiveness and response to Cetuximab in head and neck cancer., PMID:40121428
Vitamin A-Enriched Diet Increases Urothelial Cell Proliferation by Upregulating Itga3 and Areg After Cyclophosphamide-Induced Injury in Mice., PMID:40119798
Manganese-induced Precocious Puberty Alters Mammary Epithelial Cell Proliferation in Female Rats., PMID:40105700
Basal cell adhesion molecule (BCAM) promotes mesothelial-to-mesenchymal transition and tumor angiogenesis through paracrine signaling., PMID:40082910
Maternal supplementation with α-tocopherol inhibits the development of offspring food allergy, H1R signaling and ultimately anaphylaxis early in life., PMID:40073242
Inhibition of HDAC4 in granulosa cells improves co-cultured porcine oocyte maturation in vitro independently of LH., PMID:40066659
HDAC11 in ovarian granulosa cells coordinates LH in the maturation of oocytes in Tan sheep., PMID:40065721
Treg derived Amphiregulin protects from murine lupus nephritis via tissue reparative effects., PMID:40044779
Heparan sulfate regulates amphiregulin programming of tissue reparative lung mesenchymal cells during influenza A virus infection in mice., PMID:40032825
High Amphiregulin Expression in Intestinal Biopsies of Pediatric Patients with Severe Acute Graft-Versus-Host Disease., PMID:40015568
Plasma proteomics for cognitive decline and dementia-A Southeast Asian cohort study., PMID:39998981
Dissecting the Spatial and Single-Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer., PMID:39950944
Recirculating regulatory T cells mediate thymic regeneration through amphiregulin following damage., PMID:39892391
Triiodothyronine (T3) increases the expression of the amphiregulin (AREG) oncogene by activating extranuclear pathways in MCF-7 breast cancer cells., PMID:39876971
Acquired vulnerability against EGF receptor inhibition in gastric cancer promoted by class I histone deacetylase inhibitor entinostat., PMID:39864337
The X-Linked Tumor Suppressor TSPX Regulates Genes Involved in the EGFR Signaling Pathway and Cell Viability to Suppress Lung Adenocarcinoma., PMID:39858622
Neo-adjuvant FOLFOX with and without panitumumab for patients with KRAS-wt locally advanced colon cancer: results following an extended biomarker panel on the FOxTROT trial embedded phase II population., PMID:39805350
Effect of human chorionic gonadotropin on oocyte maturation and developmental competence in buffalo., PMID:39787661
BMAL1 ameliorates type 2 diabetes-induced cognitive impairment via AREG upregulation and PI3K/Akt/GSK-3β pathway activation., PMID:39762888
Identifying proteins and pathways associated with multimorbidity in 53,026 adults., PMID:39740741
A novel immune-related gene prognostic signature combining immune cell infiltration and immune checkpoint for glioblastoma patients., PMID:39697704
The impact of Benzophenone-3 on osteoarthritis pathogenesis: a network toxicology approach., PMID:39677492
Esophageal ILC2s mediate abnormal epithelial remodeling in eosinophilic esophagitis via Areg-EGFR signaling., PMID:39653767
Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia., PMID:39645657
Left atrial single-cell transcriptomics reveals amphiregulin as a surrogate marker for atrial fibrillation., PMID:39622943
Dysregulated Treg repair responses lead to chronic rejection after heart transplantation., PMID:39621314
Liver X receptor unlinks intestinal regeneration and tumorigenesis., PMID:39567700
Tristetraprolin-mediated mRNA destabilization regulates basophil inflammatory responses., PMID:39550253
Low-affinity ligands of the epidermal growth factor receptor are long-range signal transmitters in collective cell migration of epithelial cells., PMID:39546398
Amphiregulin is overexpressed in human cardiac tissue in hypothermia deaths; associations between the transcript and stress hormone levels in cardiac deaths., PMID:39506618
Protective effect of TCR-mediated MAIT cell activation during experimental autoimmune encephalomyelitis., PMID:39468055
For research use only. Not for human or drug use.
