Catalog No.
YHD12201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys274
Predicted molecular weight
33.18 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P15559
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NAD(P)H:quinone oxidoreductase 1, Azoreductase, Phylloquinone reductase, NQO1, DT-diaphorase, NAD(P)H dehydrogenase [quinone] 1, QR1, DIA4, NMOR1, Quinone reductase 1, Menadione reductase, DTD
Suk-SaiYasna Remedy, a Traditional Thai Medicine, Mitigates Stress-Induced Cognitive Impairment via Keap1-Nrf2 Pathway., PMID:40508195
The 8-Hydroxyquinoline Derivatives of 1,4-Naphthoquinone: Synthesis, Computational Analysis, and Anticancer Activity., PMID:40508142
Bioinformatics analysis of hub genes and oxidative stress-related pathways in odontogenic keratocysts., PMID:40505773
Micronutrient antioxidant supplementation alleviates valproic acid-induced oxidative stress and male infertility via the NRF2/HO-1 pathway., PMID:40505349
Omaveloxolone, But Not Dimethyl Fumarate, Improves Cardiac Function in Friedreich's Ataxia Mice With Severe Cardiomyopathy., PMID:40501183
Erianin Protects Human Umbilical Vein Endothelial Cells From Oxidized Low-Density Lipoprotein-Induced Apoptosis and Oxidative Stress Through Activation of Nuclear Factor E2-Related Factor 2 Signaling., PMID:40490908
Blockade of cysteinyl leukotriene receptor 1 alleviates asthma by inhibiting bronchial epithelial cell apoptosis and activating the Nrf2 signaling pathway., PMID:40486901
Purification, identification, and mechanism of action of novel antioxidant peptides from quinoa (Chenopodium quinoa wild.) protein hydrolysate., PMID:40482480
Human umbilical cord mesenchymal stem cell-derived exosomes mitigate acute radiation-induced intestinal oxidative damage via the Nrf2/HO-1/NQO1 signaling pathway., PMID:40478886
Plant essential oil supplementation promotes growth and attenuates LPS-induced acute liver injury through SIRT1/PGC-1α signaling pathway in nursery pigs., PMID:40468731
Emerging Therapeutic Potential of Fisetin for Nephrotoxicity, Kidney Injury, and Nephropathy: A Systematic Review., PMID:40464183
The essential oil from the rhizomes of Stahlianthus involucratus attenuates the progression of vascular aging and atherosclerosis by regulating Nrf2-mediated mitochondrial quality., PMID:40463900
EBV Reactivation-associated gene signature predicts poor prognosis in nasopharyngeal carcinoma., PMID:40457434
Hepatoprotective Effect of Meroterpenoid-Rich Fraction from the Ethanolic Extract of Sargassum sarratifolium on tert-Butyl Hydroperoxide-Induced Mice., PMID:40443236
Ethanol-induced Nrf2 suppression in the lung is mediated by AP-1-driven expression of miR-144., PMID:40442882
Study of the ameliorative effect of β-Bisabolene on ischemic stroke via COX-2 with the Keap1/Nrf2 and MAPK pathways., PMID:40441590
RETREG1-mediated reticulophagy is activated by an ATF4-CEBPG/C/EBPγ heterodimer and confers protection against lipotoxicity., PMID:40437698
Ginkgolide B inhibits ferroptosis in PC12 cells and ameliorates the oxidative stress in spinal cord injury through activating Nrf2 signaling pathway., PMID:40436481
Sulforaphane treatment of HL-60 cells protects against clozapine toxicity and protein covalent binding: implications for clozapine-induced agranulocytosis., PMID:40436238
Proteomics-Based Exploration of the Hepatoprotective Mechanism of α-Lipoic Acid in Rats with Iron Overload-Induced Liver Injury., PMID:40429916
Anti-Inflammasome Effect of Impressic Acid on Diesel Exhaust Particulate Matter-Induced NLRP1 Inflammasome via the Keap1/p62/Nrf2-Signaling Pathway in Keratinocytes., PMID:40427491
Vitamin E Inhibits Oxidative Stress and Inflammation in Stress-Induced Gastritis via Modulating Nrf2 and NF-κB Signalling Pathways., PMID:40418631
The ameliorative role of phlorotannin on aflatoxin B1-induced liver oxidative stress and mitochondrial injury is related to the activation of Nrf2 and Nrf1 signaling pathways in broilers., PMID:40405298
A CoQ10 analog ameliorates cognitive impairment and early brain injury after subarachnoid hemorrhage by regulating ferroptosis and neuroinflammation., PMID:40398356
Environmentally Relevant Lead Exposure Impacts Gene Expression in SH-SY5Y Cells Throughout Neuronal Differentiation., PMID:40397994
Nrf2 Deficiency Brings About Increased Sensitive to IR and 7,12-dimethylbenz(a)anthracene and Leukemia Predisposition., PMID:40395975
Deficiency of Aging-Related Gene Chitinase-Like 4 Impairs Olfactory Epithelium Homeostasis., PMID:40389328
Integration of Bulk RNA and Single-Cell Analyses Reveal Distinct Expression Patterns of Anoikis-Related Genes and the Immunosuppressive Role of NQO1+ Macrophages in Hepatocellular Carcinoma., PMID:40386974
Artemisinin Alleviates Alcohol-Induced Cardiotoxicity by Inhibiting Ferroptosis via the Nrf2/NQO1 Pathway In Vivo and In Vitro., PMID:40384105
Alyssin Modulates Inflammatory Mediators Expression in Interleukin-1β-Stimulated Human Periodontal Ligament Cells., PMID:40384003
Ameliorative effect of GLP1 agonist on vascular calcification in normoglycemic aged rat aorta via miR34a/SIRT6/NRF2/HO-1 signalling pathway., PMID:40383222
Transcriptomic profiling provide insights into swainsonine-induced toxic responses and activation of the aryl hydrocarbon receptor pathway., PMID:40381828
Blockade of the estrogen receptor alpha-pregnane X receptor axis protects ovariectomized mice against ethanol-induced hepatotoxicity., PMID:40381698
Oxidative stress biomarkers as novel screening tools for trisomy 21: a case-control study., PMID:40380151
Comparison of submerged and air liquid interface exposure: limitations and differences in the toxicological effects evaluated in bronchial epithelial cells., PMID:40379004
Activation of the Nrf2 pathway by a novel bipyrazole compound mitigates doxorubicin-induced cardiotoxicity in Wistar albino rats., PMID:40374058
Molecular pharmacokinetic mechanism of JBP485 against aristolochic acid I (AAI) -induced nephrotoxicity., PMID:40371353
TCA Cycle Intermediate Mitigates Di(2-ethylhexyl) Phthalate-Induced Cholestatic Liver Injury Through Modulation of the Nrf2/NQO1 Signalling Axis., PMID:40370325
Nrf2 Activation and Antioxidant Properties of Chromone-Containing MTDLs for Alzheimer's Disease Treatment., PMID:40363853
Sigesbeckia pubescens makino alleviates ulcerative colitis in mice by modulating the Nrf2/Keap1 pathway., PMID:40356967
CPT1A/HIF-1α positive feedback loop induced fatty acid oxidation metabolic pathway contributes to the L-ascorbic acid-driven angiogenesis in breast cancer., PMID:40355947
Platelet-Released Growth Factors (PRGFs) Activate NRF2-ARE and Modulate Inflammatory Response in an NRF2-Dependent Manner in Primary Human Keratinocytes., PMID:40353553
[Improvement effect and mechanism of Wuling San on TGF-β1-induced fibrosis, inflammation, and oxidative stress damage in HK-2 cells]., PMID:40350908
Radiation-triggerable bioreactors enable bioenergetic reprograming of cancer stem cell plasticity via targeted arginine metabolism disruption for augmented radio-immunotherapy., PMID:40344881
Screening of pivotal oncogenes modulated by DNA methylation in hepatocellular carcinoma and identification of atractylenolide I as an anti-cancer drug., PMID:40325252
The induction of quinone oxidoreductases NQO1 and NQO2 by clozapine: Potential implications for clozapine-induced agranulocytosis., PMID:40311769
Metformin's mechanism in reducing oxidative stress and promoting bone regeneration in T2DM rat BMMSCs: A focus on NRF2-GPX7 signaling pathway., PMID:40306480
Methyleugenol alleviates pulmonary vascular remodeling in rats with high-altitude pulmonary hypertension by improving pulmonary smooth muscle cell function., PMID:40306181
Alterations of DNA Repair and Immune Infiltration in Radiation-Induced Intestinal Injury., PMID:40297667
Hirsutine attenuated oxidative stress and autophagy in diabetic kidney disease through Keap1/Nrf2 pathway., PMID:40288825
For research use only. Not for human or drug use.
