Catalog No.
YHC89901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu22-Asn91
Predicted molecular weight
10.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11684
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Clara cells 10 kDa secretory protein, CC10, UP-1, Uteroglobin, SCGB1A1, UP1, UGB, CCSP, Clara cell phospholipid-binding protein, Urine protein 1, Secretoglobin family 1A member 1, CCPBP, Urinary protein 1, CC16
Mechanisms on How Matricellular Microenvironments Sustain Idiopathic Pulmonary Fibrosis., PMID:40508199
Club cell secretory protein (CC16) polymorphisms in preterm neonates with respiratory distress syndrome and bronchopulmonary dysplasia., PMID:40374938
Surfactant Protein D and Club Cell Secretory Protein as Biomarkers of Disease Severity and Fostamatinib Efficacy in Severe COVID-19., PMID:40267041
rhCC16 Suppresses Cellular Senescence and Ameliorates COPD-Like Symptoms by Activating the AMPK/Sirt1-PGC-1-α-TFAM Pathway to Promote Mitochondrial Function., PMID:40259209
Plasma club cell secretory protein reflects early lung injury: comprehensive epidemiological evidence., PMID:40240158
Clara cell 16 kDa protein: an important marker for COVID-19 severity., PMID:40236699
Edaravone alleviates Pseudomonas aeruginosa associated-acute lung injury by inhibiting inflammation and promoting anti-microbial peptide production., PMID:40158431
Circulating CC16, immune response to Mycoplasma pneumoniae and lung function: a population-based, multi-cohort study., PMID:40090526
SCGB1A1 as a Key Regulator of Splenic Immune Dysfunction in COPD: Insights From a Murine Model., PMID:40060920
Dupilumab efficacy in relation to changes in club cell secretory protein 16., PMID:40043947
GNGT1 remodels the tumor microenvironment and promotes immune escape through enhancing tumor stemness and modulating the fibrinogen beta chain-neutrophil extracellular trap signaling axis in lung adenocarcinoma., PMID:39958208
Regulation of lung progenitor plasticity and repair by fatty acid oxidation., PMID:39927460
Systemic Changes in Early Pregnancy in the Mare: An Integrated Proteomic Analysis of Blood Plasma, Histotroph, and Yolk Sac Fluid at Day 14 Post-Ovulation., PMID:39912552
Nomogram model using serum Club cell secretory protein 16 to predict prognosis and acute exacerbation in patients with idiopathic pulmonary fibrosis., PMID:39794841
Hypoxia-inducible factor 2 regulates alveolar regeneration after repetitive injury in three-dimensional cellular and in vivo models., PMID:39772774
Dynamics of the blood plasma proteome during hyperacute HIV-1 infection., PMID:39632834
Nasal effects of environmental tobacco smoke exposure in children with allergic rhinitis., PMID:39613232
Bioinformatics Analysis and Experimental Validation to Identify Key Glycosylation-Related Genes in Asthma., PMID:39606642
The impact of tangeretin combined with whey protein on exercise-induced bronchoconstriction in professional athletes: a placebo-controlled trial., PMID:39422600
Impact of metals exposure on lung function and serum club cell secretory protein among schoolchildren: A mixture and mediation analysis., PMID:39413513
Changes in serum uteroglobin level in type 2 diabetes mellitus patients., PMID:39403586
Single-cell transcriptomics reveals e-cigarette vapor-induced airway epithelial remodeling and injury., PMID:39342154
SCGB1A1 as a novel biomarker and promising therapeutic target for the management of HNSCC., PMID:39268163
Association between plasma CC16 levels and lung function changes in coke oven workers: A cohort study from 2014 to 2023., PMID:39241606
Application value of P-selectin and Clara cell secretory protein 16 expression in children with severe adenovirus pneumonia., PMID:39228315
Airway Serous Cells: A Comparative Study of Spatial Distribution and Abundance among Species., PMID:39220634
Cobalt exposure and pulmonary function reduction in chronic obstructive pulmonary disease patients: the mediating role of club cell secretory protein., PMID:39182083
Distinctive field effects of smoking and lung cancer case-control status on bronchial basal cell growth and signaling., PMID:39160511
Clara cell 10 (CC10) protein attenuates allergic airway inflammation by modulating lung dendritic cell functions., PMID:39078462
Detection of serum CC16 by a rapid and ultrasensitive magnetic chemiluminescence immunoassay for lung disease diagnosis., PMID:39072498
An easy-to-perform protocol for culturing primary murine lung tumor cells as organoids., PMID:38971450
Inflammatory imbalance in tracheal aspirate of very preterm newborns is associated with airway obstruction and lung function deficiencies at school age: a cohort study., PMID:38862162
NF-κB/RelA signaling in secretoglobin progenitors mediates plasticity and MMP-induced barrier disruption in house dust mite-induced allergic asthma., PMID:38713619
Prognosis and immunotherapy significances of a cancer-associated fibroblasts-related gene signature in lung adenocarcinoma., PMID:38279482
The combination of propylene glycol and vegetable glycerin e-cigarette aerosols induces airway inflammation and mucus hyperconcentration., PMID:38253598
Pneumoprotein CC16 in the Umbilical Cord Blood of Preterm Neonates., PMID:38160675
Club cell protein (CC16) in serum as an effect marker for small airway epithelial damage caused by diesel exhaust and blasting fumes in potash mining., PMID:38110551
CC16 drives VLA-2-dependent SPLUNC1 expression., PMID:38053993
The Impact of CC16 on Pulmonary Epithelial-Driven Host Responses during Mycoplasma pneumoniae Infection in Mouse Tracheal Epithelial Cells., PMID:37566063
Circulating CC16 and Asthma: A Population-based, Multicohort Study from Early Childhood through Adult Life., PMID:37523710
Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway., PMID:37515878
Effects of lifestyle and associated diseases on serum CC16 suggest complex interactions among metabolism, heart and lungs., PMID:37330047
Discovery of therapeutic targets of quercetin for endometrial carcinoma patients infected with COVID-19 through network pharmacology., PMID:36969077
Ionocyte-Specific Regulation of Cystic Fibrosis Transmembrane Conductance Regulator., PMID:36952679
Validation of Prognostic Club Cell Secretory Protein (CC16) Cut-point in an Independent ALTA Cohort., PMID:36814995
CC16 augmentation reduces exaggerated COPD-like disease in Cc16-deficient mice., PMID:36787195
Whole lung proteome of an acute epithelial injury mouse model in comparison to spatially resolved proteomes., PMID:36641648
Extracellular vesicle-encapsulated CC16 as novel nanotherapeutics for treatment of acute lung injury., PMID:36635966
Mouse models of lung-specific SARS-CoV-2 infection with moderate pathological traits., PMID:36457995
Club Cell Secretory Protein in Lung Disease: Emerging Concepts and Potential Therapeutics., PMID:36450281
For research use only. Not for human or drug use.
