Catalog No.
YHC91101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp15-Leu259
Predicted molecular weight
29.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11926
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ornithine decarboxylase, ODC, ODC1
Baicalein alleviates chronic acute stress-induced irritable bowel syndrome-like symptoms in rats via modulating the ODC1/NF-κB pathway and oxidative stress., PMID:40409117
Monitoring ODC activity and polyamines in Bachmann-Bupp syndrome patient biological samples., PMID:40382142
Enhanced recombinant xylanase B expression in Komagataella phaffii through metabolic engineering of methanol utilization., PMID:40317293
Uric acid-induced cardiomyocytic polyamines' insufficience: a potential mechanism mediates cardiomyocytic injury., PMID:40260285
Plasma protein levels and hepatocellular carcinoma: a Mendelian randomization study with drug screening implications., PMID:40252200
Oleic acid regulates CD4+ T cells differentiation by targeting ODC1-mediated STAT5A phosphorylation in Vogt-Koyanagi-Harada disease., PMID:40203473
Lamb Performance and Meat Quality: The Impact of Chromium in High-Concentrate Diets and Its Molecular Effects on Skeletal Muscle During Finishing Phase., PMID:40011411
Polyamine depletion limits progression of acute leukaemia., PMID:39985426
Androgen receptor drives polyamine synthesis creating a vulnerability for prostate cancer., PMID:39711733
Liver transcriptomics-metabolomics integration reveals biological pathways associated with fetal programming in beef cattle., PMID:39532951
Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma., PMID:39531507
Partial Lipodystrophy Affecting the Extremities in a Young Woman With Autoimmune Polyglandular Syndrome 1., PMID:39318439
Genetic predisposition of suicidal behavior: variants in GRIN2B, GABRG2, and ODC1 genes in attempted and completed suicide in two Balkan populations., PMID:39297975
Impact of polyamine supplementation on GnRH expression, folliculogenesis, and puberty onset in young mice., PMID:39217649
A surge in endogenous spermidine is essential for rapamycin-induced autophagy and longevity., PMID:39212197
Disrupting YAP1-mediated glutamine metabolism induces synthetic lethality alongside ODC1 inhibition in osteosarcoma., PMID:39115605
Aryl hydrocarbon receptor confers protection against macrophage pyroptosis and intestinal inflammation through regulating polyamine biosynthesis., PMID:39113799
Canonical and Non-Canonical Functions of Erythropoietin and Its Receptor in Mature Nucleated Erythrocytes of Western Clawed Frog, Xenopus tropicalis., PMID:39093279
Polyamine Anabolism Promotes Chemotherapy-Induced Breast Cancer Stem Cell Enrichment., PMID:39058337
Ame-miR-1-3p of bee venom reduced cell viability through the AZIN1/OAZ1-ODC1-polyamines pathway and enhanced the defense ability of honeybee (Apis mellifera L.)., PMID:38767730
Eflornithine for treatment of high-risk neuroblastoma., PMID:38749882
FOXA1 co-activates circODC1 and ODC1 in HPV-positive cervical cancer cell growth., PMID:38743820
Effect of cryopreservation on Odc1 and RhoA genes expression in diapausing mouse blastocysts., PMID:38712681
Clustering of predicted loss-of-function variants in genes linked with monogenic disease can explain incomplete penetrance., PMID:38671509
Pirin Promotes the Progression of Non-Small-Cell Lung Cancer by Increasing ODC1 to Suppress Autophagy., PMID:38648079
A clinical-stage Nrf2 activator suppresses osteoclast differentiation via the iron-ornithine axis., PMID:38569557
Effects of Spermine Synthase Deficiency in Mesenchymal Stromal Cells Are Rescued by Upstream Inhibition of Ornithine Decarboxylase., PMID:38473716
Elevated expression of HIGD1A drives hepatocellular carcinoma progression by regulating polyamine metabolism through c-Myc-ODC1 nexus., PMID:38395945
Approval of DFMO for high-risk neuroblastoma patients demonstrates a step of success to target MYC pathway., PMID:38316994
Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state., PMID:38216963
Mechanistic exploration of Yiqi Liangxue Shengji prescription on restenosis after balloon injury by integrating metabolomics with network pharmacology., PMID:37602438
Influence of the concentrate inclusion level in a grass silage-based diet on hepatic transcriptomic profiles in Holstein-Friesian dairy cows in early lactation., PMID:37474362
Regulation of synthesis of polyamines by progesterone, estradiol, and their receptors in uteri of cyclic ewes†., PMID:37418162
Metabolomics and molecular docking analysis of antibiotic exposure in Bifidobacterium adolescentis., PMID:37204035
Persistent Coxsackievirus B3 Infection in Pancreatic Ductal Cells In Vitro Downregulates Cellular Polyamine Metabolism., PMID:37097178
Untargeted metabolomic analysis of ischemic injury in human umbilical vein endothelial cells reveals the involvement of arginine metabolism., PMID:36998018
The oncogenic properties of the EWSR1::CREM fusion gene are associated with polyamine metabolism., PMID:36966162
Cottonseed hydrolysate supplementation alters metabolic and proteomics responses in Chinese hamster ovary cell cultures., PMID:36892270
Circular RNA circ_0003028 regulates cell development through modulating miR-498/ornithine decarboxylase 1 axis in hepatocellular carcinoma., PMID:36730287
Role of circulating exosomal biomarkers and their diagnostic accuracy in pancreatic cancer., PMID:36660044
Gasdermin D Deficiency in Vascular Smooth Muscle Cells Ameliorates Abdominal Aortic Aneurysm Through Reducing Putrescine Synthesis., PMID:36567267
Ornithine decarboxylase supports ILC3 responses in infectious and autoimmune colitis through positive regulation of IL-22 transcription., PMID:36279426
LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages., PMID:35978195
SMARCE1 promotes neuroblastoma tumorigenesis through assisting MYCN-mediated transcriptional activation., PMID:35978151
Evaluation of a Pooling Chemoproteomics Strategy with an FDA-Approved Drug Library., PMID:35969671
Roles of lncRNA LVBU in regulating urea cycle/polyamine synthesis axis to promote colorectal carcinoma progression., PMID:35906392
Arginine Regulates Zygotic Genome Activation in Porcine Embryos Under Nutrition Restriction., PMID:35812864
Compromised glycolysis contributes to foot process fusion of podocytes in diabetic kidney disease: Role of ornithine catabolism., PMID:35780908
Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer's disease., PMID:35738259
Evaluation of the Influence of Biosurface Design on the Interaction between the Regulatory Peptide RS1-reg and ODC1 Reveals a Membrane-Dependent Affinity Increase., PMID:35735188
For research use only. Not for human or drug use.
