Catalog No.
EHC21201
Expression system
Insect Cells
Species
Homo sapiens (Human)
Protein length
Met1-Lys434
Predicted molecular weight
48.4 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P06733
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Non-neural enolase, 2-phospho-D-glycerate hydro-lyase, MPB-1, ENO1, Plasminogen-binding protein, Enolase 1, C-myc promoter-binding protein, Alpha-enolase, MBP-1, MBPB1, MPB1, ENO1L1, NNE, Phosphopyruvate hydratase
The Direct and Individual Transcriptional Function of the Human Homodimeric and Heterodimeric Basic Helix-Loop-Helix Transcription Factors E47 and Scleraxis., PMID:40512054
Integrative Single-Cell and Bulk RNA Sequencing Identifies a Glycolysis-Related Prognostic Signature for Predicting Prognosis in Pancreatic Cancer., PMID:40507914
HPD is an RNA-Binding Protein Sustaining Ovarian Cancer Cell Glycolysis, Tumor Growth, and Drug Resistance., PMID:40491422
Targeting the JAK2-STAT3-UCHL3-ENO1 axis suppresses glycolysis and enhances the sensitivity to 5-FU chemotherapy in TP53-mutant colorectal cancer., PMID:40487654
β-suppressor protein 1 (ARRB1)-△exon13 modulates the progression of glioblastoma via combination with glycolysis-related proteins., PMID:40486495
The 1p/19q co-deletion induces targetable and imageable vulnerabilities in glucose metabolism in oligodendrogliomas., PMID:40475477
Application of serum anti-ENO1 and anti-SSNA1 antibody biomarkers in predicting the prognosis of gastric cancer., PMID:40469915
Isorhamnetin Attenuates Isoproterenol-Induced Myocardial Injury by Reducing ENO1 (Alpha-Enolase) in Cardiomyocytes., PMID:40427461
Rewired glycolysis by DTL accelerates oncometabolite L-lactate generation to promote breast cancer progression., PMID:40391156
Esculetin inhibits liver cancer by targeting glucose-6-phosphate isomerase mediated glycolysis., PMID:40373632
Epitopes targeted by autoantibodies in presymptomatic individuals predict early rheumatoid arthritis., PMID:40348635
Paeoniflorin Directly Targets ENO1 to Inhibit M1 Polarization of Microglia/Macrophages and Ameliorates EAE Disease., PMID:40332313
EMC2 promotes breast cancer progression and enhances sensitivity to PDK1/AKT inhibition by deubiquitinating ENO1., PMID:40303285
SIRT4 Promotes Pancreatic Cancer Stemness by Enhancing Histone Lactylation and Epigenetic Reprogramming Stimulated by Calcium Signaling., PMID:40298941
Elucidating the Role and Mechanism of Alpha-Enolase in Senescent Amelioration via Metabolic Reprogramming., PMID:40289552
Machine learning technique-based four-autoantibody test for early detection of esophageal squamous cell carcinoma: a multicenter, retrospective study with a nested case-control study., PMID:40264204
SIX1 enhances aerobic glycolysis and progression in cervical cancer through ENO1., PMID:40234326
KAT3B Promotes the Glycolysis and Malignant Progression of Lung Cancer by Mediating the Succinylation Modification of PKM2., PMID:40226997
Proteomic insights into lymph node metastasis in breast cancer subtypes: Key biomarkers and pathways., PMID:40179440
Annexin A2 binds the 3'-UTR of H2AX mRNA and regulates histone-H2AX-derived hypoxia-inducible factor 1-alpha activation., PMID:40164417
Investigation of new autoantibodies in urothelial bladder cancer for biomarker discovery using immunoproteomics., PMID:40163213
RNA-binding protein expression based machine learning model predicts metastasis and treatment outcome of testicular cancer., PMID:40138122
Deletion of ENO1 sensitizes pancreatic cancer cells to gemcitabine via MYC/RRM1-mediated glycolysis., PMID:40121292
A comprehensive study on the impact of Ligustrum vicaryi L. fruit polysaccharide on myocardial fibrosis through animal experiments, network pharmacology and molecular docking., PMID:40051434
Inhibition of the MLL1-WDR5 interaction modulates epithelial to mesenchymal transition and metabolic pathways in triple-negative breast cancer cells., PMID:40043619
Structural and molecular dysfunctions in granulosa cells: A key contributor to porcine follicular atresia., PMID:40043493
Colon cancer-cell-specific drug delivery by gemcitabine conjugated with peptide chain targeting ENO1., PMID:40024451
Proteomic Analysis of Human Follicular Fluid-Derived Exosomes Reveals That Insufficient Folliculogenesis in Aging Women is Associated With Infertility., PMID:40024376
Immunohistochemical Analysis of Inter-Alpha-Trypsin Inhibitor Heavy Chain 2 and Enolase 1 in Canine Mammary Tumors: Associations with Tumor Aggressiveness and Prognostic Significance., PMID:40005870
CDCA3-MYC positive feedback loop promotes bladder cancer progression via ENO1-mediated glycolysis., PMID:39980052
In vitro protein expression profile of cultivated muscle cells from Labeo rohita., PMID:39966484
ENO1/Hsp70 Interaction Domains: In Silico and In Vitro Insight for a Putative Therapeutic Target in Cancer., PMID:39959117
Aerobic exercise acts differentially on proteins from glucose and glycogen pathways in the SOL and PL muscles of offspring rats submitted to a low-protein maternal diet., PMID:39954356
Integrative machine learning model of RNA modifications predict prognosis and treatment response in patients with breast cancer., PMID:39948551
Role of NAT10-mediated ac4C acetylation of ENO1 mRNA in glycolysis and apoptosis in non-small cell lung cancer cells., PMID:39948547
Proteomic analysis of whole blood to investigate the therapeutic effects of nervonic acid on cerebral ischemia-reperfusion injury in rats., PMID:39936033
HSP90 co-regulates the formation and nuclear distribution of the glycolytic output complex to promote resistance and poor prognosis in gastric cancer patients., PMID:39930487
ENO1-BACE2-mediated LDLR cleavage promotes liver cancer progression by remodelling cholesterol metabolism., PMID:39914449
A cellular model of TDP-43 induces phosphorylated TDP-43 aggregation with distinct changes in solubility and autophagy dysregulation., PMID:39887552
In vitro and in vivo activity of 1,2,3,4,6-O-pentagalloyl-glucose against Candida albicans., PMID:39853121
Targeting enolase 1 reverses bortezomib resistance in multiple myeloma through YWHAZ/Parkin axis., PMID:39828712
Activation of mTOR/HK2 signaling mitigates effects of PYCR2 depletion in colorectal cells., PMID:39808866
Discovering Cell-Targeting Ligands and Cell-Surface Receptors by Selection of DNA-Encoded Chemical Libraries against Cancer Cells without Predefined Targets., PMID:39794292
ENO1 promotes PDAC progression by inhibiting CD8+ T cell infiltration through upregulating PD-L1 expression via HIF-1α signaling., PMID:39752908
FOSL1 transcriptionally dictates the Warburg effect and enhances chemoresistance in triple-negative breast cancer., PMID:39748430
Identifying ENO1 as a protein target of chlorogenic acid to inhibit cellular senescence and prevent skin photoaging in mice., PMID:39741388
Exploring variances in meat quality between Qingyuan partridge chicken and Cobb broiler: Insights from combined multi-omics analysis., PMID:39721276
The expression of glycolysis-related proteins in urine significantly increases after running., PMID:39717827
ANGPTL4 mediated mesothelial-mesenchymal transition in pulmonary fibrosis: a potential therapeutic target., PMID:39707362
In-silico identification and validation of Silibinin as a dual inhibitor for ENO1 and GLUT4 to curtail EMT signaling and TNBC progression., PMID:39689434
For research use only. Not for human or drug use.
