Catalog No.
YHC17801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp238-Leu396
Predicted molecular weight
20.44 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05783
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cytokeratin-18, CYK18, K18, Keratin, type I cytoskeletal 18, KRT18, CK-18, Keratin-18, Cell proliferation-inducing gene 46 protein
Novel therapeutic targets for metabolism-related diseases: proteomic Mendelian randomization and colocalization analyses., PMID:40453312
RETREG1-mediated reticulophagy is activated by an ATF4-CEBPG/C/EBPγ heterodimer and confers protection against lipotoxicity., PMID:40437698
[Study of the role of biomarkers in determining the course of non-alcoholic fatty liver disease in children with obesity]., PMID:40418137
The Functional Impact of the Noncoding SNP rs3741442 on Orofacial Clefting., PMID:40353495
Integrated lncRNA and mRNA Transcriptome Analyses of IGF1 and IGF2 Stimulated Ovaries Reveal Genes and Pathways Potentially Associated with Ovarian Development and Oocyte Maturation in Golden Pompano (Trachinotus ovatus)., PMID:40281968
Diagnostic Value of Serum Cytokeratin 18 for the Staging of Liver Inflammation and Fibrosis: A Meta-Analysis., PMID:40202219
RNA-binding protein expression based machine learning model predicts metastasis and treatment outcome of testicular cancer., PMID:40138122
Metabolic and Hepatic Profiles of Non-Obese and Obese Metabolic Dysfunction-Associated Steatotic Liver Disease in Adolescents: The Role of FibroScan Parameters,Fibroblast Growth Factor-21, and Cytokeratin-18., PMID:39910885
Molecular Characterization of Cancer Preventive and Therapeutic Potential of Three Antistress Compounds, Triethylene Glycol, Withanone, and Withaferin A., PMID:39859209
Cytokeratin 18 fragment in liver inflammation and fibrosis: Systematic review and meta-analysis., PMID:39832704
HCG18 Promotes Cell Proliferation and Stemness in Cholangiocarcinoma via the miR-194-5p/KRT18/MAPK Signaling., PMID:39776371
Mass spectrometric detection of keratins in tear fluid., PMID:39761842
The role of KRT18 in lung adenocarcinoma development: integrative bioinformatics and experimental validation., PMID:39729139
TEAD3 and TEAD4 play overlapping role in bovine preimplantation development., PMID:39679917
An integrative multi-omics analysis reveals a multi-analyte signature of pancreatic ductal adenocarcinoma in serum., PMID:39666045
Therapeutic targets for hepatocellular carcinoma identified using proteomics and Mendelian randomization., PMID:39477889
Transcriptome analysis identifies potential molecular mechanisms for growth of fast muscle in Chinese perch juvenile., PMID:39454973
Differentiation of human umbilical cord mesenchymal stem cells into functional intestinal epithelial cells via conditioned medium co-culture., PMID:39427828
Cytokeratin 18 in nonalcoholic fatty liver disease: value and application., PMID:39387822
Establishment of an immortalized sheep mammary epithelial cell line for studying milk fat and protein synthesis., PMID:39322983
Impact of Keratins 8 and 18 Genetic Variants on the Severity of Alcoholic Liver Disease., PMID:39278623
Unveiling the impact of cell death-related genes and immune dynamics on drug resistance in lung adenocarcinoma: a risk score model and functional insights., PMID:39269650
KRT18 as a Novel Biomarker of Urothelial Papilloma while Evaluating Low-Grade Papillary Urothelial Neoplasms: Bi-Center Analysis., PMID:39191209
Skeletal muscle adaptations following eccentric contractions are not mediated by keratin 18., PMID:39169838
Comprehensive Analysis and In Vitro Verification of Endothelial-Mesenchymal Transition-Related Genes in Moyamoya Disease., PMID:39134827
FBLN2 is associated with basal cell markers Krt14 and ITGB1 in mouse mammary epithelial cells and has a preferential expression in molecular subtypes of human breast cancer., PMID:39110274
Development and characterization of an immortalized nasopharyngeal epithelial cell line to explore airway physiology and pathology in yak (Bos grunniens)., PMID:39086762
Serum Cytokeratin-18 levels as a prognostic biomarker in advanced liver disease: a comprehensive meta-analysis., PMID:39023658
HMGB1-Mediated Cell Death-A Crucial Element in Post-Hepatectomy Liver Failure., PMID:39000266
Thyroxine regulates pig Sertoli cell line proliferation and maturation through the IKK/NFκB and p38 MAPK signaling pathways., PMID:38981313
Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration., PMID:38865240
Clinical Utility of Cytokeratins for Accurate Diagnosis of Hepatocellular Carcinoma Among Hepatitis C Virus High-Risk Patients., PMID:38679993
Simultaneous quantification of six proteins related to liver injury using nano liquid chromatography-tandem mass spectrometry., PMID:38605420
Rapid induction of dopaminergic neuron-like cells from human fibroblasts by autophagy activation with only 2-small molecules., PMID:38524239
Cytokeratin-18 is a sensitive biomarker of alanine transaminase increase in a placebo-controlled, randomized, crossover trial of therapeutic paracetamol dosing (PATH-BP biomarker substudy)., PMID:38521541
Simple method for isolation and culture of primary buffalo (Bubalus bubalis) endometrial epithelial cells (pBuEECs) and its characterization using high throughput proteomics approach., PMID:38490065
A Composite Blood Biomarker Including AKR1B10 and Cytokeratin 18 for Progressive Types of Nonalcoholic Fatty Liver Disease., PMID:38311058
Transcriptomic and proteomic strategies to reveal the mechanism of Gymnocypris przewalskii scale development., PMID:38310220
Identification and characterization of multipotential stem cells in immortalized normal ovarian surface epithelial cells., PMID:38243680
Understanding the effects of per- and polyfluoroalkyl substances on early skin development: Role of ciliogenesis inhibition and altered microtubule dynamics., PMID:38163615
The biomarkers associated with epithelial-mesenchymal transition in human keloids., PMID:37980270
Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity., PMID:37949677
A novel lncRNA-mediated epigenetic regulatory mechanism in periodontitis., PMID:37928259
Optimisation of a Method for the Differentiation of Human Umbilical Cord-derived Mesenchymal Stem Cells Toward Renal Epithelial-like Cells., PMID:37831588
KRT18 regulates trophoblast cell migration and invasion which are essential for embryo implantation., PMID:37620903
Molecular mechanisms regulating natural menopause in the female ovary: a study based on transcriptomic data., PMID:37564980
LINC01137/miR-186-5p/WWOX: a novel axis identified from WWOX-related RNA interactome in bladder cancer., PMID:37519886
Zerumbone-incorporated liquid crystalline nanoparticles inhibit proliferation and migration of non-small-cell lung cancer in vitro., PMID:37439806
The Role of Interferon Receptors α/β/γ Ablation During Western Diet-Induced Obesity and Insulin Resistance in the Inflectional Model AG129 Mice Strain., PMID:37428556
Proteome Analysis of the Antiproliferative Activity of the Novel Chitooligosaccharide-Gallic Acid Conjugate against the SW620 Colon Cancer Cell Line., PMID:37371778
For research use only. Not for human or drug use.
