Catalog No.
YHC21801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ile285
Predicted molecular weight
35.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P06753
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Gamma-tropomyosin, Tropomyosin-5, Tropomyosin alpha-3 chain, hTM5, Tropomyosin-3, TPM3
Development and application of a whole transcriptome sequencing assay for the detection of gene fusions in clinical cancer specimens., PMID:40340691
NTRK1 Gene Fusions Are Frequent in Juvenile Xanthogranuloma., PMID:40235191
Application of Omics in Donkey Meat Research: A Review., PMID:40218384
A novel pathogenic variant c.44A > G (p. Asp15Gly) in TPM3 causing the phenotype of CMYP4A: A case report., PMID:40115162
Cutaneous Hemangioma With Epithelioid Features Harboring TPM3/4::ALK Fusions : A Distinct Entity or a Molecular Variant of Epithelioid Hemangioma?, PMID:40070162
An accurate DNA and RNA based targeted sequencing assay for clinical detection of gene fusions in solid tumors., PMID:40021757
NTRK rearranged spindle cell neoplasm of the uterine cervix: a rare case report and literature review., PMID:40011900
The clinical significance and biological function of tropomyosin 3 in ulcerative colitis., PMID:39938429
The m6A modification regulates the composition of myofiber types in chicken skeletal muscle., PMID:39919566
[NTRK gene fusion and molecular pathological characteristics of mismatch repair deficient colorectal cancer]., PMID:39863528
Renal cell carcinoma with ALK-TPM3 gene fusion and ALK amplification: A case report and literature review., PMID:39813766
Modulation of Abnormal Vasoconstriction Through 2-Hydroxyisobutyrylation of Tropomyosin 3 Lys141: Targeting Histone Deacetylase 3 as a Key Approach., PMID:39719422
ALK-Rearranged Renal Cell Carcinoma: A Study of Three Cases With Clinicopathologic Features and Effect of Postoperative Adjuvant Immunotherapy., PMID:39626326
Philadelphia chromosome-positive or Philadelphia chromosome-like B-cell precursor acute lymphoblastic leukemia with multilineage involvement in pediatric patients: a report of two cases and literature review., PMID:39470068
Recurrent CLTC::SYK fusions and CSF1R mutations in juvenile xanthogranuloma of soft tissue., PMID:39316650
Matrix stiffness regulates the protein profile of extracellular vesicles of pancreatic cancer cell lines., PMID:39279557
hsa_circ_0000129 targets miR-383-5p/tropomyosin 3 axis to facilitate ovarian cancer progression., PMID:39219187
Mechanisms of tropomyosin 3 in the development of malignant tumors., PMID:39170461
[ALK rearranged Spitz melanocytoma: a clinicopathological and molecular genetic analysis of two cases]., PMID:39103263
Weighted gene co-expression network analysis and single-cell sequence analysis uncover immune landscape and reveal hub genes of necroptosis in macrophages in myocardial ischaemia-reperfusion injury., PMID:39079349
NTRK-fused central nervous system tumours: clinicopathological and genetic insights and response to TRK inhibitors., PMID:39014476
Myosin-1C differentially displaces tropomyosin isoforms altering their inhibition of motility., PMID:38971309
Neurotrophic tyrosine receptor kinase gene fusions in adult and pediatric patients with solid tumors: a clinicogenomic biobank and record linkage study of expression frequency and patient characteristics from Finland., PMID:38967220
Spitz Melanoma With SLC20A1::ALK Fusion: A Novel Fusion Previously Undescribed in Spitz Melanocytic Neoplasm., PMID:38941542
The Role of TPM3 in Protecting Cardiomyocyte from Hypoxia-Induced Injury via Cytoskeleton Stabilization., PMID:38928503
Induction of resistance to neurotrophic tropomyosin-receptor kinase inhibitors by HMGCS2 via a mevalonate pathway., PMID:38923428
Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics., PMID:38878676
Single molecule visualization of tropomyosin isoform organization in the mammalian actin cytoskeleton., PMID:38872463
Feasibility of two-step approach for screening NTRK fusion in two major subtypes of non-small cell lung cancer within a large cohort., PMID:38866255
ALK-Rearranged Renal Cell Carcinoma: A Multi-Institutional Study of 9 Cases With Expanding the Morphologic and Molecular Genetic Spectrum., PMID:38852815
Identification of hub genes related to metastasis and prognosis of osteosarcoma and establishment of a prognostic model with bioinformatic methods., PMID:38847690
Targeting F-actin stress fibers to suppress the dedifferentiated phenotype in chondrocytes., PMID:38823166
Molecular cloning of TPM3 gene in qinchuan cattle and its effect on myoblast proliferation and differentiation., PMID:38775564
Uncommon molecular alterations in follicular-derived thyroid carcinoma: A single institution study., PMID:38763089
Motor properties of Myosin 5c are modulated by tropomyosin isoforms and inhibited by pentabromopseudilin., PMID:38606007
Primary NTRK -rearranged Spindle Cell Neoplasm of the Gastrointestinal Tract: A Clinicopathological and Molecular Analysis of 8 Cases., PMID:38525823
Focal adhesions contain three specialized actin nanoscale layers., PMID:38514695
Sarcomeric tropomyosin expression during human iPSC differentiation into cardiomyocytes., PMID:38470291
Identification and validation of protein biomarkers for predicting gastrointestinal stromal tumor recurrence., PMID:38455069
Spitz melanocytic neoplasms with MLPH::ALK fusions: Report of two cases with previously unreported features and literature review., PMID:38444194
TMT-labeled quantitative malonylome analysis on the longissimus dorsi muscle of Laiwu pigs reveals the role of ACOT7 in fat deposition., PMID:38395145
Cerebrospinal fluid proteomic signatures are associated with symptom severity of first-episode psychosis., PMID:38340697
A Novel Circular RNA circITGa9 Predominantly Generated in Human Heart Disease Induces Cardiac Remodeling and Fibrosis., PMID:38323094
Variant ALK-fusion positive anaplastic large cell lymphoma (ALCL): A population-based paediatric study of the NHL-BFM study group., PMID:38279625
Molecular Screening in Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma: Anaplastic Lymphoma Kinase Analysis, Next-Generation Sequencing Fusion Gene Detection, and T-Cell Receptor Immunoprofiling., PMID:38266918
RNF20 Regulates Oocyte Meiotic Spindle Assembly by Recruiting TPM3 to Centromeres and Spindle Poles., PMID:38240347
Variants in tropomyosins TPM2 and TPM3 causing muscle hypertonia., PMID:38219297
Myopathy-causing mutation R91P in the TPM3 gene drastically impairs structural and functional properties of slow skeletal muscle tropomyosin γβ-heterodimer., PMID:38185233
CD74/SLC34A2-ROS1 Fusion Variants Involving the Transmembrane Region Predict Poor Response to Crizotinib in NSCLC Independent of TP53 Mutations., PMID:38070598
Troponin and a Myopathy-Linked Mutation in TPM3 Inhibit Cofilin-2-Induced Thin Filament Depolymerization., PMID:38003645
For research use only. Not for human or drug use.
