Catalog No.
VHC42101
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
CSF1, Macrophage colony-stimulating factor 1, CSF-1, Lanimostim, M-CSF, MCSF
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P09603
Applications
ELISA, FCM, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0052
ZEB2 upregulation modulates the polarization of TAMs toward the immunosuppressive state in EGFR-TKI-resistant NSCLC., PMID:40510028
miR-484 in Hippocampal Astrocytes of Aged and Young Rats Targets CSF-1 to Regulate Neural Progenitor/Stem Cell Proliferation and Differentiation Into Neurons., PMID:40304412
Fusion of glioma-associated mesenchymal stem/stromal cells with glioma cells promotes macrophage recruitment and M2 polarization via m6A modification of CSF1., PMID:40287444
Endothelial dysfunction drives atherosclerotic plaque macrophage-dependent abdominal aortic aneurysm formation., PMID:40263614
Therapy-induced senescent glioblastoma cells sustain a procancer immune microenvironment by activating DDX58-mediated STAT1 signaling., PMID:40259469
Integrating network pharmacology and in vivo pharmacological validation to explore the gastroprotective mechanism of Sotetsuflavone against indomethacin-induced gastric ulcer in rats: Involvement of JAK2/STAT3 pathway., PMID:40258498
New soluble CSF-1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in pleural mesothelioma., PMID:40101804
Disruption of GPSM1/CSF1 signaling reprograms tumor-associated macrophages to overcome anti-PD-1 resistance in colorectal cancer., PMID:40010765
Neutrophil extracellular traps impede cancer metastatic seeding via protease-activated receptor 2-mediated downregulation of phagocytic checkpoint CD24., PMID:40010762
Decreased miR-128-3p in serum exosomes from polycystic ovary syndrome induces ferroptosis in granulosa cells via the p38/JNK/SLC7A11 axis through targeting CSF1., PMID:39966422
Molecular Profiling of Odontoclasts during Physiological Tooth Replacement., PMID:39876039
Inhibition of the extracellular matrix protein fibulin-3 reduces immunosuppressive signaling in tumor stem cells and increases macrophage activation against glioblastoma., PMID:39763756
Ribosomal protein S3A (RPS3A), as a transcription regulator of colony-stimulating factor 1 (CSF1), promotes glioma progression through regulating the recruitment and autophagy-mediated M2 polarization of tumor-associated macrophages., PMID:39560749
Nicotine promotes M2 macrophage polarization through α5-nAChR/SOX2/CSF-1 axis in lung adenocarcinoma., PMID:39487876
LncRNA MEG3 suppresses hepatocellular carcinoma by stimulating macrophage M1 polarization and modulating immune system via inhibiting CSF-1 in vivo/vitro studies., PMID:39396590
ASH1L in Hepatoma Cells and Hepatic Stellate Cells Promotes Fibrosis-Associated Hepatocellular Carcinoma by Modulating Tumor-Associated Macrophages., PMID:39377228
Knockdown of microglial iron import gene, Slc11a2, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer's disease., PMID:39334471
Helicobacter pylori induce circ_0046854 to regulate microRNA-511-3p/CSF1 axis and enhance the resistance of gastric cancer to cisplatin., PMID:39291620
EBV-associated epithelial cancers cells promote vasculogenic mimicry formation via a secretory cross-talk with the immune microenvironment., PMID:39267775
Heterozygous missense CSF1R variants hamper in vitro CD34+-derived dendritic cell generation but not in vivo dendritic cell development., PMID:39182279
Upregulation of MELK promotes chemoresistance and induces macrophage M2 polarization via CSF-1/JAK2/STAT3 pathway in gastric cancer., PMID:39135038
L-Wnk1 Deletion in Smooth Muscle Cells Causes Aortitis and Inflammatory Shift., PMID:38979610
Knockdown of microglial iron import gene, DMT1, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer's disease., PMID:38978579
The development status of PET radiotracers for evaluating neuroinflammation., PMID:38932754
Paracrine Ovarian Cancer Cell-Derived CSF1 Signaling Regulates Macrophage Migration Dynamics in a 3D Microfluidic Model that Recapitulates In Vivo Infiltration Patterns in Patient-Derived Xenografts., PMID:38807270
Mechanistic Characterization of Cancer-associated Fibroblast Depletion via an Antibody-Drug Conjugate Targeting Fibroblast Activation Protein., PMID:38747612
Tumor microenvironment restricts IL-10 induced multipotent progenitors to myeloid-lymphatic phenotype., PMID:38640116
Selenium maintains intestinal epithelial cells to activate M2 macrophages against deoxynivalenol injury., PMID:38636715
Optical controlled and nuclear targeted CECR2 competitor to downregulate CSF-1 for metastatic breast cancer immunotherapy., PMID:38615488
CSF1R inhibition reprograms tumor-associated macrophages to potentiate anti-PD-1 therapy efficacy against colorectal cancer., PMID:38432446
Keratinocyte integrin α3β1 induces expression of the macrophage stimulating factor, CSF-1, through a YAP/TEAD-dependent mechanism., PMID:38340968
The interplay of Cxcl10+/Mmp14+ monocytes and Ccl3+ neutrophils proactively mediates silica-induced pulmonary fibrosis., PMID:38335607
Engineered Microchannel Scaffolds with Instructive Niches Reinforce Endogenous Bone Regeneration by Regulating CSF-1/CSF-1R Pathway., PMID:38321645
Colony-stimulating factor-1 receptor inhibition combined with paclitaxel exerts effective antitumor effects in the treatment of ovarian cancer., PMID:38303927
The CSF-1R inhibitor pexidartinib affects FLT3-dependent DC differentiation and may antagonize durvalumab effect in patients with advanced cancers., PMID:38266104
AhR and CYP1B1 Control Oxygen Effects on Bone Marrow Progenitor Cells: The Enrichment of Multiple Olfactory Receptors as Potential Microbiome Sensors., PMID:38069208
Macrophage-hitchhiked arsenic/AB bionic preparations for liver cancer., PMID:37981869
The genetic background determines material-induced bone formation through the macrophage-osteoclast axis., PMID:37898023
Regulatory effects of Zishen Yutai Pill on endometrial epithelial response in vitro in immunology microenvironment., PMID:37809636
Niche-specific macrophage loss promotes skin capillary aging., PMID:37662387
The Transcriptome Landscape of the In Vitro Human Airway Epithelium Response to SARS-CoV-2., PMID:37569398
Discovery of therapeutic targets for spinal cord injury based on molecular mechanisms of axon regeneration after conditioning lesion., PMID:37507810
Blockade of tumor-derived colony-stimulating factor 1 (CSF1) promotes an immune-permissive tumor microenvironment., PMID:37505292
Periradicular tissue fluid-derived biomarkers for apical periodontitis: An in vitro methodological and in vivo cross-sectional study., PMID:37464545
Ionizable Lipid with Supramolecular Chemistry Features for RNA Delivery In Vivo., PMID:37312676
A perspective into the relationships between amphibian (Xenopus laevis) myeloid cell subsets., PMID:37305910
MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcoma., PMID:37279073
A highly selective purine-based inhibitor of CSF1R potently inhibits osteoclast differentiation., PMID:37141705
Fibroblastic reticular cells provide a supportive niche for lymph node-resident macrophages., PMID:36991561
Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy., PMID:36951731
For research use only. Not for human or drug use.
