InVivoMAb Anti-Human BMP6 (Iv0059)

Catalog No.

VHD49501

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

VG-1-R, VG-1-related protein, Bone morphogenetic protein 6, VGR-1, BMP-6, VGR, BMP6

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P22004

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0059

Melatonin Promotes Cerebral Angiogenesis in Ischemic Mice via BMP6/Smad1/5/9 Pathway., PMID:40274709

LncRNA MRF targeting FSHR inhibits the osteogenic differentiation of BMSCs and bone defect repair through the regulation of the cAMP-PKA-CREB signaling pathway., PMID:40264197

The GPR30-Mediated BMP-6/HEP/FPN Signaling Pathway Inhibits Ferroptosis in Bone Marrow Mesenchymal Stem Cells to Alleviate Osteoporosis., PMID:40076648

Sevuparin strongly reduces hepcidin expression in cells, mice, and healthy human volunteers., PMID:39619244

The Influence of BMP6 on Serotonin and Glucose Metabolism., PMID:39063084

miR-455/GREM1 axis promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing M2 macrophage polarization., PMID:38970064

The BMP2 prodomain promotes dimerization and cleavage of BMP6 homodimers and BMP2/6 heterodimers in vivo., PMID:38948827

Silibinin is a suppressor of the metastasis-promoting transcription factor ID3., PMID:38484626

BMP6 inhibits gastric cancer growth and predicts good prognosis., PMID:38482225

Serum Iron Overload Activates the SMAD Pathway and Hepcidin Expression of Hepatocytes via SMURF1., PMID:38426189

Improvement of Mouse Preantral Follicle Survival and Development following Co-Culture with Ovarian Parenchyma Cell Suspension., PMID:38368519

The hepatokine FGL1 regulates hepcidin and iron metabolism during anemia in mice by antagonizing BMP signaling., PMID:38232308

BMP-ACVR1 Axis is Critical for Efficacy of PRC2 Inhibitors in B-Cell Lymphoma., PMID:38229201

Superoxide dismutase 2 scavenges ROS to promote osteogenic differentiation of human periodontal ligament stem cells by regulating Smad3 in alveolar bone-defective rats., PMID:37921754

Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage., PMID:37602966

An H2 S-BMP6 Dual-Loading System with Regulating Yap/Taz and Jun Pathway for Synergistic Critical Limb Ischemia Salvaging Therapy., PMID:37531238

CREB-H is a stress-regulator of hepcidin gene expression during early postnatal development., PMID:37493829

H3K27me3-modulated Hofbauer cell BMP2 signalling enhancement compensates for shallow trophoblast invasion in preeclampsia., PMID:37331163

FKBP12 inhibits hepcidin expression by modulating BMP receptors interaction and ligand responsiveness in hepatocytes., PMID:37199280

The hepatokine FGL1 regulates hepcidin and iron metabolism during the recovery from hemorrhage-induced anemia in mice., PMID:37066218

Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers., PMID:36726183

Genesis of osteoclasts on calcium phosphate ceramics and their role in material-induced bone formation., PMID:36371003

Iron metabolism disorder regulated by BMP signaling in hypoxic pulmonary hypertension., PMID:36343841

iPSC-neural crest derived cells embedded in 3D printable bio-ink promote cranial bone defect repair., PMID:36333414

Anticeramide Improves Sjögren's Syndrome by Blocking BMP6-Induced Th1., PMID:36281063

NORAD promotes multiple myeloma cell progression via BMP6/P-ERK1/2 axis., PMID:36126794

The use of heparin/polycation coacervate sustain release system to compare the bone regenerative potentials of 5 BMPs using a critical sized calvarial bone defect model., PMID:36031459

Glycochenodeoxycholate Affects Iron Homeostasis via Up-Regulating Hepcidin Expression., PMID:35956351

Differential effects of Smad2 and Smad3 in regulation of macrophage phenotype and function in the infarcted myocardium., PMID:35780861

Foxp1 and Foxp4 Deletion Causes the Loss of Follicle Stem Cell Niche and Cyclic Hair Shedding by Inducing Inner Bulge Cell Apoptosis., PMID:35759955

Evolved Bmp6 enhancer alleles drive spatial shifts in gene expression during tooth development in sticklebacks., PMID:34849839

Bone morphogenetic protein 6-mediated crosstalk between endothelial cells and hepatocytes recapitulates the iron-sensing pathway in vitro., PMID:34740612

Differentiation Behaviour of Adipose-Derived Stromal Cells (ASCs) Seeded on Polyurethane-Fibrin Scaffolds In Vitro and In Vivo., PMID:34440186

Eucommia ulmoides Polysaccharides Attenuate Rabbit Osteoarthritis by Regulating the Function of Macrophages., PMID:34421623

Calcitonin increases hepatic hepcidin expression through the BMP6 of kidney in mice., PMID:34098241

A BMP/Activin A Chimera Induces Posterolateral Spine Fusion in Nonhuman Primates at Lower Concentrations Than BMP-2., PMID:33950879

Alginate/chitosan modified immunomodulatory titanium implants for promoting osteogenesis in vitro and in vivo., PMID:33947577

Matriptase-2 and Hemojuvelin in Hepcidin Regulation: In Vivo Immunoblot Studies in Mask Mice., PMID:33800732

Black pepper prevents anemia of inflammation by inhibiting hepcidin over-expression through BMP6-SMAD1/ IL6-STAT3 signaling pathway., PMID:33771600

BMP-6 carrying metal organic framework-embedded in bioresorbable electrospun fibers for enhanced bone regeneration., PMID:33545881

Osteoinduction within adipose tissue fragments by heterodimeric bone morphogenetic Proteins-2/6 and -2/7 versus homodimeric bone morphogenetic protein-2: Therapeutic implications for bone regeneration., PMID:33527563

Endothelial specific YY1 deletion restricts tumor angiogenesis and tumor growth., PMID:33235311

Gene Expression Regulation and Secretory Activity of Mesenchymal Stem Cells upon In Vitro Contact with Microarc Calcium Phosphate Coating., PMID:33081386

Synthetic ceramic macroporous blocks as a scaffold in ectopic bone formation induced by recombinant human bone morphogenetic protein 6 within autologous blood coagulum in rats., PMID:33052447

Suppression of the TGF-β pathway by a macrolide antibiotic decreases fibrotic responses by ocular fibroblasts in vitro., PMID:33047019

Possible mechanisms by which silkworm faeces extract ameliorates adenine-induced renal anaemia in rats., PMID:33022342

Orphan Nuclear Receptor ERRγ Is a Novel Transcriptional Regulator of IL-6 Mediated Hepatic BMP6 Gene Expression in Mice., PMID:32998264

Synergistic interaction of hTGF-β3 with hBMP-6 promotes articular cartilage formation in chitosan scaffolds with hADSCs: implications for regenerative medicine., PMID:32854680

Biology of bone morphogenetic protein in bone repair and regeneration: A role for autologous blood coagulum as carrier., PMID:32841742

A novel autologous bone graft substitute comprised of rhBMP6 blood coagulum as carrier tested in a randomized and controlled Phase I trial in patients with distal radial fractures., PMID:32730930

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