New mouse model based on adenocarcinoma 4T1 cells expressing HPV16 E6 and E7 applied to assess the efficacy of therapeutic and prophylactic E6/E7-based HPV16 vaccines., PMID:40470197
Myeloid-specific HNRNPA2B1 deficiency disrupts macrophage function and in vivo responses., PMID:40414614
An immune-based predictive model for HBV clearance: validation in multicenter cohorts and mechanistic insights from in vivo studies., PMID:40399947
The mitochondrial protease ClpP is a metabolic vulnerability and an immunogenic trigger against multiple myeloma., PMID:40300074
Interferon-γ and IL-27 positively regulate type 1 regulatory T cell development during adaptive tolerance., PMID:40276760
Immune response against antibiotic-resistant and antibiotic-sensitive staphylococcus aureus in a rat model of implant infection., PMID:40246912
Rutin attenuates bleomycin-induced acute lung injury via miR-9-5p mediated NF-κB signaling inhibition: network pharmacology analysis and experimental evidence., PMID:40110126
Genome-wide KAS-Seq mapping of leukocytes in ischemia-reperfusion model reveals IL7R as a potential therapeutic target for ischemia-reperfusion injury., PMID:39979392
Signature cytokine-associated transcriptome analysis of effector γδ T cells identifies subset-specific regulators of peripheral activation., PMID:39881001
Application of the Sponge Model Implants in the Study of Vaccine Memory in Mice Previously Immunized with LBSap., PMID:39771984
Oral Delivery of miR146a Conjugated to Cerium Oxide Nanoparticles Improves an Established T Cell-Mediated Experimental Colitis in Mice., PMID:39771552
Polyfunctional IL-21+ IFNG+ T follicular helper cells contribute to checkpoint inhibitor diabetes mellitus and can be targeted by JAK inhibitor therapy., PMID:39677814
Identification of a Highly Functional Effector CD8 + T Cell Program after Transplantation in Mice and Humans., PMID:39677722
Effect of hypoxia-induced mIL15 expression on expansion and memory progenitor stem-like TILs in vitro., PMID:39650651
Selective regulation of IFN-γ and IL-4 co-producing unconventional T cells by purinergic signaling., PMID:39560665
Cytokine production in an ex vivo model of SARS-CoV-2 lung infection., PMID:39497823
NOSTRIN is involved in benign prostatic hyperplasia via inhibition of proliferation, oxidative stress, and inflammation in prostate epithelial cells., PMID:39434759
Taxus chinensis (Pilg.) Rehder fruit attenuates aging behaviors and neuroinflammation by inhibiting microglia activation via TLR4/NF-κB/NLRP3 pathway., PMID:39413938
Physiologically Achievable Concentration of 2-Deoxy-D-Glucose Stimulates IFN-γ Secretion in Activated T Cells In Vitro., PMID:39408714
Cellular and molecular determinants of bacterial burden in leprosy granulomas revealed by single-cell multimodal omics., PMID:39321499
Ginsenoside Rg3 targets glycosylation of PD-L1 to enhance anti-tumor immunity in non-small cell lung cancer., PMID:39247194
Adipose-derived exosomes as a preventative strategy against complications in hyaluronic acid filler applications: A comprehensive in vivo analysis., PMID:39181844
Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity., PMID:39116204
NKT cells promote Th1 immune bias to dengue virus that governs long-term protective antibody dynamics., PMID:39088280
Characterization of active alkaloids and metabolites in rats after oral administration of Zuojin Pill using UHPLC-Q-TOF-MS combined with bioinformatics and molecular docking analyses., PMID:38986349
An antibody to IL-1 receptor 7 protects mice from LPS-induced tissue and systemic inflammation., PMID:38983847
A "Prime and Expand" strategy using the multifunctional fusion proteins to generate memory-like NK cells for cell therapy., PMID:38960949
Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng., PMID:38821052
Lack of the IFN-γ signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions., PMID:38743761
Analysis of intestinal epithelial cell responses to Cryptosporidium highlights the temporal effects of IFN-γ on parasite restriction., PMID:38718306
A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification., PMID:38697116
Recombinant probiotic Lactococcus lactis delivering P62 mitigates moderate colitis in mice., PMID:38680913
Chitosan-Loaded Lagenaria siceraria and Thymus vulgaris Potentiate Antibacterial, Antioxidant, and Immunomodulatory Activities against Extensive Drug-Resistant Pseudomonas aeruginosa and Vancomycin-Resistant Staphylococcus aureus: In Vitro and In Vivo Approaches., PMID:38671876
A genome-wide association study identified PTPN2 as a population-specific susceptibility gene locus for primary biliary cholangitis., PMID:38652555
Increased levels of villus-derived exosomal miR-29a-3p in normal pregnancy than uRPL patients suppresses decidual NK cell production of interferon-γ and exerts a therapeutic effect in abortion-prone mice., PMID:38627796
CRIF1 deficiency induces FOXP3LOW inflammatory non-suppressive regulatory T cells, thereby promoting antitumor immunity., PMID:38536932
Maternal recognition of pregnancy in the pig: A servomechanism involving sex steroids, cytokines and prostaglandins., PMID:38522133
Pig conceptuses utilize extracellular vesicles for interferon-gamma-mediated paracrine communication with the endometrium†., PMID:38501810
CD4 T cell-secreted IFN-γ in Sjögren's syndrome induces salivary gland epithelial cell ferroptosis., PMID:38471652
Design, Synthesis, and Antitumor Activity Evaluation of Novel VISTA Small Molecule Inhibitors., PMID:38412237
Parasite-induced IFN-γ regulates host defense via CD115 and mTOR-dependent mechanism of tissue-resident macrophage death., PMID:38377133
Exosome lncRNA IFNG-AS1 derived from mesenchymal stem cells of human adipose ameliorates neurogenesis and ASD-like behavior in BTBR mice., PMID:38368393
Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype., PMID:38342608
NK cell-triggered CCL5/IFNγ-CXCL9/10 axis underlies the clinical efficacy of neoadjuvant anti-HER2 antibodies in breast cancer., PMID:38167224
CD8 T cell response and its released cytokine IFN-γ are necessary for lung alveolar epithelial repair during bacterial pneumonia., PMID:37954603
Preadipocytes in human granulation tissue: role in wound healing and response to macrophage polarization., PMID:37904253
A meta-analysis of epitopes in prostate-specific antigens identifies opportunities and knowledge gaps., PMID:37679223
Predicting potential lncRNA biomarkers for lung cancer and neuroblastoma based on an ensemble of a deep neural network and LightGBM., PMID:37655066
NLRP3 inflammasome-driven IL-1β and IL-18 contribute to lipopolysaccharide-induced septic cardiomyopathy., PMID:37172930
Evaluation of the in vivo and in vitro interleukin-12 p40 and p35 subunit response in yellowtail (Seriola quinqueradiata) to heat-killed Lactobacillus plantarum strain L-137 (HK L-137) supplementation, and immersion challenge with Lactococcus garvieae., PMID:37168607