Catalog No.
VHJ72801
Species reactivity
Human
Host species
Human
Isotype
IgG4, Kappa
Clonality
Monoclonal
Target
FIL1D, Interleukin-1 family member 5, IL-36Ra, IL1HY1, Interleukin-36 receptor antagonist protein, IL1RP3, IL-1RP3, IL-1ra homolog 1, Interleukin-1-like protein 1, IL-1-related protein 3, IL1L1, Interleukin-1 HY1, IL-1HY1, Interleukin-1 delta, FIL1 delta, IL-1 delta, IL-1L1, Interleukin-1 receptor antagonist homolog 1, IL36RN, IL1F5, IL-1F5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UBH0
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0035
Transcriptome Analysis of Porphyromonas gingivalis Lipopolysaccharide-Induced Early Gene Expression in Human Gingival Keratinocytes., PMID:39412375
Spesolimab, the first-in-class anti-IL-36R antibody: From bench to clinic., PMID:39373152
TLR7/8 Activation in Immune Cells and Muscle by RNA-Containing Immune Complexes: Role in Inflammation and the Pathogenesis of Myositis., PMID:39279150
A homozygous loss-of-function variant in the MPO gene is associated with generalized pustular psoriasis., PMID:36585391
Enhanced IL-36R signaling promotes barrier impairment and inflammation in skin and intestine., PMID:33443029
Interleukin-36 receptor antagonist attenuates atherosclerosis development by inhibiting NLRP3 inflammasome., PMID:32488871
Effect of black chokeberry on skeletal muscle damage and neuronal cell death., PMID:32018343
Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies., PMID:28726542
Mutation in IL36RN impairs the processing and regulatory function of the interleukin-36-receptor antagonist and is associated with DITRA syndrome., PMID:28603914
IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8., PMID:18284608