InVivoMAb Anti-Human IL17A (Iv0029)

Catalog No.

VHH28801

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

CTLA-8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL-17A, IL17A, CTLA8, IL-17, Interleukin-17A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q16552

Applications

ELISA, FCM, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0029

Dihydromyricetin, the active component of rattan tea alleviates symptoms of systemic sclerosis and atopic dermatitis through modulation of RORγt and IL17A production in T cells., PMID:40513840

SLC4A10 impedes atherosclerosis by diminishing IFN-γ/GZMB levels of CD8+ T cells via the MAPK pathway., PMID:40510365

A Novel Small Molecule ITK Inhibitor Suppresses Th2/Th17 Differentiation and Attenuates Airway Inflammation in a Mouse Model of HDM-Induced Asthma., PMID:40509664

The role of Bifidobacterium animalis QC08 in antibiotic-associated diarrhea in mice., PMID:40492055

Potentially Elevated Rheumatoid Arthritis Risk due to Chemotherapy-Induced Inflammation in Prostate Cancer With Bone Metastasis., PMID:40489190

KRAS regulates IL-17 signal activity by affect the metastasis of osteosarcoma via an IL-17A-dependent manner., PMID:40486048

A tryptophol-containing emulgel ameliorates imiquimod-induced mice psoriasis., PMID:40461662

Comparative Analysis of Cytokine Expression Profiles in Prostate Cancer Patients., PMID:40427694

The Inhibitory Effect of the Active Ingredients in the Bushen Huoxue Formula on the IL-17A Signaling Pathway and Its Alleviating Effect on Osteoarthritis., PMID:40421263

Dissecting key contributions of Th2 and Th17 cytokines to atopic dermatitis pathophysiology., PMID:40409379

Oral roflumilast suppresses pro-inflammatory cytokine signaling and reduces CD4+ T cell and neutrophil infiltration in psoriasis., PMID:40403838

Therapeutic potential of Platycodin D in allergic asthma through anti-inflammatory and anti-remodeling effects., PMID:40397997

Metabolic reprogramming of interleukin-17-producing γδ T cells promotes ACC1-mediated de novo lipogenesis under psoriatic conditions., PMID:40360755

Broussonetia papyrifera ameliorates imiquimod-induced psoriasis-like skin inflammation in mice by modulating the TLR4/NF-κB and PI3K/AKT signaling pathways., PMID:40333872

Unrestrained MyD88 Signaling in A20-Deficient Keratinocytes Triggers T-Cell-Dependent Psoriatic Arthritis-Like Disease., PMID:40316204

Regulatory T cells suppress GM-CSF-producing T helper cells via IL-2 modulation to restrain immunopathology., PMID:40315053

Curcumin-loaded nanoemulsion for acute lung injury treatment via nebulization: Formulation, optimization and in vivo studies., PMID:40314003

Dexmedetomidine improve lung inflammation by regulating autophagy and apoptosis of CD4+ T cell via AMPK/mTOR signaling., PMID:40311186

Paraquat exposure triggers amyloid-β and α-synuclein aggregation in the prefrontal cortex of mice: Suppression of microglial phagocytosis via IL-17A., PMID:40300355

Ursolic acid attenuates sarcopenia through IL-17a-related gut-muscle axis in senile diabetic mice and myotube model., PMID:40294722

Andrographolide sulfonate alleviates rheumatoid arthritis by inhibiting glycolysis-mediated activation of PI3K/AKT to restrain Th17 cell differentiation., PMID:40274350

Feed restriction as a model for small intestinal permeability in nursery pigs., PMID:40259486

PTGS2 Silencing Inhibits Ferroptosis in Staphylococcus Aureus-induced Osteomyelitis By Blocking the IL-17A Signaling Pathway., PMID:40257651

Discovery and Optimization of Potent and Highly Selective PARP14 Inhibitors for the Treatment of Atopic Dermatitis., PMID:40239060

Brevilin A inhibits IL‑17A‑induced inflammation in psoriasis by modulating HSP 70., PMID:40211707

Xiao-Chai-Hu granule alleviates influenza virus-induced pneumonia by regulating TLR4-PI3K-Akt/p38 MAPK-NF-κB pathways., PMID:40204248

MCPIP3 orchestrates the balance of epidermal proliferation and differentiation., PMID:40200325

Microneedle system carrying Momordin Ic-loaded ROS-responsive hydrogel ameliorates psoriasis via targeted anti-inflammatory and reactive oxygen species (ROS)-scavenging mechanisms., PMID:40199433

Febrile temperature-regulated TRPV1 in CD4+ T cells mediates neuroinflammation in complex febrile seizures., PMID:40197540

Neutrophils negatively control IL-17A-producing γδ T cell frequencies in a contact-dependent manner under physiological conditions., PMID:40181985

Copper oxide nanoparticles induce pulmonary inflammation via triggering cellular cuproptosis., PMID:40180017

Identification of novel IL17-related genes as prognostic and therapeutic biomarkers of psoriasis using comprehensive bioinformatics analysis and machine learning., PMID:40175394

PLK1 Mediates the Proliferation and Contraction of Airway Smooth Muscle Cells and Has a Role in T2-High Asthma with Neutrophilic Inflammation Model., PMID:40162075

Autoimmunity and clinical pathology amelioration in SLE by dexamethasone primed mesenchymal stem cell derived conditioned media., PMID:40158179

miR-200 family: Gatekeepers of fibrinolytic regulation in lung pathologies during acute lung injury., PMID:40127710

Enhance Efferocytosis and Block the Macrophages-Platelets Feedback Loop for Targeted Treatment of Psoriasis., PMID:40113447

Amelioration of imiquimod induced psoriasis through reduction in IL-17A and Th17 population by dihydromyricetin involves regulation of RORγt pathway., PMID:40112600

Piezoelectric nanofilms fabricated by coaxial electrospun polycaprolactone/Barium titanate promote Achilles tendon regeneration by reducing IL-17A/NF-κB-mediated inflammation., PMID:40110584

Exosomes Derived from Adipose Stem Cells Inhibit Skin T Cells Activation and Alleviate Wound Inflammation., PMID:40100757

ITGAX promotes Th17-cell differentiation and drives pathogenesis in pediatric ulcerative colitis., PMID:40099533

Knockdown of ANXA3 regulates NF-κB/STAT3 pathway to alleviate inflammation and hyperproliferation in psoriasis models., PMID:40088019

Impact of obesity on the CCR6-CCL20 axis in epidermal γδ T cells and IL-17A production in murine wound healing and psoriasis., PMID:40073267

STING Deficiency Promotes Th17-Like Tfh to Aggravate the Experimental Autoimmune Uveitis., PMID:40042874

The protective role of muscone in the development of COPD., PMID:40034710

Screening of aqueous plant extracts for immunomodulatory effects on immune cells and cytokine production: In vitro and in vivo analyses., PMID:40034324

NETs-CD44-IL-17A Feedback Loop Drives Th17-Mediated Inflammation in Behçet's Uveitis., PMID:40013981

The Diagnostic Significance of SLC26A2 and Its Potential Role in Ulcerative Colitis., PMID:40002875

Filgotinib Improves Experimental Pulmonary Fibrosis by Modulating JAK1/STAT3/SOCS3/IL-17A Signalling., PMID:39995397

Extracts of Portulaca oleracea and Patrinia scabiosaefolia relieve ultraviolet B-induced skin injury in solar dermatitis mice via inhibiting IL-17/CCL2 pathway and oxidative stress., PMID:39991764

Targeting the IL-17A pathway for therapy in early-stage tendinopathy., PMID:39988349

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