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Neisseria meningitidis Antigens/Antibodies
2024-07-08 84

Neisseria meningitidis

Meningococcal disease, caused by the capsulated Gram-negative bacterium Neisseria meningitidis, is a communicable disease primarily transmitted through close contact or droplet aerosols, can rapidly progress and cause severe complications or death.

There are at least 12 identified N. meningitidis serogroups, including A, B, C, W, X, and Y. Current quadrivalent capsular polysaccharide-protein conjugate vaccines effectively prevent disease caused by four serogroups (A, C, Y, and W); however, these vaccines do not provide protection against serogroup B (MenB).

Given the recent outbreaks of meningococcal serogroup B (MenB) on school campuses, developing a vaccine for serogroup B is an urgent public health priority. vaccine development has been challenging due to the poor immunogenicity of polysaccharide-based vaccines. Consequently, vaccine development has shifted focus towards identifying outer membrane proteins that can elicit broad and protective immune responses. FHbp, NadA and NHBA are three promising MenB vaccine candidates.

Neisseria meningitidis

Figure 1 Schematic representation of Neisseria meningitidis serogroup B (MenB)

 

AntibodySystem proudly introduces the top-tier viral antigen/antibody library, SAA Vir®. This extensive collection includes over 1,000 rigorously tested products from more than 100 virus types/subtypes and 400 strains, with high-quality antigens expressed in eukaryotic cells. The SAA Vir® line features a unique catalog of bacterial and viral antigens, including RSV, Flu, COVID-19, HPV, Hantavirus, Ebola, and DENV, along with proteins, antibodies, and related kits to meet the needs of scientific research and vaccine development.

 

Protein
Catalog No. Product Name
YXX13301 Recombinant Neisseria meningitidis NadA Protein,N-His
YXX23401 Recombinant Neisseria meningitidis pilE Protein,N-His
YXX23402 Recombinant Neisseria meningitidis pilE Protein,N-His
YXX14901 Recombinant Neisseria meningitidis FHbp Protein, C-His
YXX23501 Recombinant Neisseria meningitidis neuA Protein, C-His
YXX23502 Recombinant Neisseria meningitidis neuA Protein, C-His-Strep
YXX13201 Recombinant Neisseria meningitidis NHBA Protein, N-His
Polyclonal Antibody
Catalog No. Product Name
PVV39801 Anti-JEVNS3/Serine protease NS3 PolyclonalAntibody
PXX13301 Anti-Neisseria meningitidis NadA PolyclonalAntibody
PXX23402 Anti-Neisseria meningitidis pilE Polyclonal Antibody
PXX14901 Anti-Neisseria meningitidis FHbp Polyclonal Antibody
PXX23501 Anti-Neisseria meningitidis neuA Polyclonal Antibody
Monoclonal Antibody
catalog No. ProductName
RXX02140 Anti-Neisseria meningitidis group B LPS/Lipopolysaccharide Antibody(SAA1462)
RXX13401 Anti-Neisseria meningitidis porA/Outer membrane porin protein Antibody (MN16C13F4)
RXX13201 Anti-Neisseria meningitidis NHBA/Dextranase Antibody(10C3)
RXX13301 Anti-Neisseria meningitidis NadA/Neisseria adhesin A Antibody(G9)
RXX14901 Anti-Neisseria meningitidis FHbp Antibody(1A12)
RXX14902 Anti-Neisseria meningitidis FHbp/GNA1870/LP2086 Antibody(SAA2080)

 

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