Catalog No.
                        PXX23402
                        
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Species reactivity
                        
                        Neisseria meningitidis                        
                                                
                                            Host species
                        
                        Rabbit                        
                                                
                                            Isotype
                        
                        IgG                        
                                                
                                            Clonality
                        
                        Polyclonal                        
                                                
                                            Immunogen
                        
                        E. coli - derived recombinant Neisseria meningitidis pilE (Gln25-Ser163).                        
                                                
                                            
                                            Tested applications
                        
                        ELISA: 1:4000-1:8000, WB: 1:1000-1:4000                        
                                                
                                            Target
                        
                        Pilin, pilE                        
                                                
                                            
                                            
                                            
                                            
                                            Purification
                        
                        Purified by antigen affinity column.                        
                                                
                                            Accession
                        
                        Q51237                        
                                                
                                            
                                            Applications
                        
                        ELISA, IHC, WB                        
                                                
                                            Form
                        
                        Liquid                        
                                                
                                            Storage buffer
                        
                        0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Stability and Storage
                        
                        Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.                        
                                                
                                            
                                            
                                            
                                            
                                            Associated products
                        
                        Q51237                        
                                                
                                        
                 
                
                
                                            Pilus PilA of the naturally competent HACEK group pathogen Aggregatibacter actinomycetemcomitans stimulates human leukocytes and interacts with both DNA and proinflammatory cytokines., PMID:36374775
                                            The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus., PMID:34725157
                                            Opc expression, LPS immunotype switch and pilin conversion contribute to serum resistance of unencapsulated meningococci., PMID:23028802
                                            The meningococcal minor pilin PilX is responsible for type IV pilus conformational changes associated with signaling to endothelial cells., PMID:22778100
                                            Testing the vaccine potential of PilV, PilX and ComP, minor subunits of Neisseria meningitidis type IV pili., PMID:21803096
                                            Sequence conservation of pilus subunits in Neisseria meningitidis., PMID:20457291
                                            Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili., PMID:15249686
                                            The pathogenic neisseriae contain an inactive rpoN gene and do not utilize the pilE sigma54 promoter., PMID:9479056
                                            Characterization of a class II pilin expression locus from Neisseria meningitidis: evidence for increased diversity among pilin genes in pathogenic Neisseria species., PMID:9199428
                                            Antigenic variation of pilin regulates adhesion of Neisseria meningitidis to human epithelial cells., PMID:8332064
                                            Identification of epitopes recognized by monoclonal antibodies SM1 and SM2 which react with all pili of Neisseria gonorrhoeae but which differentiate between two structural classes of pili expressed by Neisseria meningitidis and the distribution of their encoding sequences in the genomes of Neisseria spp., PMID:2483993
                                            Neisseria meningitidis C114 contains silent, truncated pilin genes that are homologous to Neisseria gonorrhoeae pil sequences., PMID:2895102
                                            Inter-strain homology of pilin gene sequences in Neisseria meningitidis isolates that express markedly different antigenic pilus types., PMID:2889791