Isolation of human monoclonal antibodies from 4CMenB vaccinees reveals PorB and LOS as the main OMV components inducing cross-strain protection., PMID:40308602
OpcA and PorB are novel bactericidal antigens of the 4CMenB vaccine in mice and humans., PMID:37045859
Deletion of major porins from meningococcal outer membrane vesicle vaccines enhances reactivity against heterologous serogroup B Neisseria meningitidis strains., PMID:32037226
Immunogenicity profiling of protein antigens from capsular group B Neisseria meningitidis., PMID:31048732
Heterogeneity in non-epitope loop sequence and outer membrane protein complexes alters antibody binding to the major porin protein PorB in serogroup B Neisseria meningitidis., PMID:28708335
Human IgG1, IgG3, and IgG3 Hinge-Truncated Mutants Show Different Protection Capabilities against Meningococci Depending on the Target Antigen and Epitope Specificity., PMID:27307451
Improving the immunogenicity of a trivalent Neisseria meningitidis native outer membrane vesicle vaccine by genetic modification., PMID:27269057
A meningococcal NOMV-FHbp vaccine for Africa elicits broader serum bactericidal antibody responses against serogroup B and non-B strains than a licensed serogroup B vaccine., PMID:26709637
FetA Antibodies Induced by an Outer Membrane Vesicle Vaccine Derived from a Serogroup B Meningococcal Isolate with Constitutive FetA Expression., PMID:26466091
Immune responses to a recombinant, four-component, meningococcal serogroup B vaccine (4CMenB) in adolescents: a phase III, randomized, multicentre, lot-to-lot consistency study., PMID:26232542
A novel meningococcal outer membrane vesicle vaccine with constitutive expression of FetA: A phase I clinical trial., PMID:25982025
Oral administration of recombinant Neisseria meningitidis PorA genetically fused to H. pylori HpaA antigen increases antibody levels in mouse serum, suggesting that PorA behaves as a putative adjuvant., PMID:25750999
Study of effect of substitution of the penultimate amino acid residue on expression, structure, and functional properties of Yersinia pseudotuberculosis OmpY porin., PMID:25108332
Bactericidal antibody against a representative epidemiological meningococcal serogroup B panel confirms that MATS underestimates 4CMenB vaccine strain coverage., PMID:23954380
Phase variation of PorA, a major outer membrane protein, mediates escape of bactericidal antibodies by Neisseria meningitidis., PMID:23403557
Preclinical safety and immunogenicity evaluation of a nonavalent PorA native outer membrane vesicle vaccine against serogroup B meningococcal disease., PMID:23273968
Analysis of the bactericidal response to an experimental Neisseria meningitidis vesicle vaccine., PMID:22461527
Cloning, expression and purification of outer membrane protein PorA of Neisseria meningitidis serogroup B., PMID:22169784
Fatal Neisseria meningitidis serogroup X sepsis in immunocompromised patients in Spain. Virulence of clinical isolates., PMID:22108049
A phase 1 study of a meningococcal native outer membrane vesicle vaccine made from a group B strain with deleted lpxL1 and synX, over-expressed factor H binding protein, two PorAs and stabilized OpcA expression., PMID:21199704
Characterisation and immune responses to meningococcal recombinant porin complexes incorporated into liposomes., PMID:19607954
IgA1 antibodies specific for outer membrane protein PorA modulate the interaction between Neisseria meningitidis and the epithelium., PMID:19486642
Genetically modified L3,7 and L2 lipooligosaccharides from Neisseria meningitidis serogroup B confer a broad cross-bactericidal response., PMID:19289516
A DNA fusion vaccine induces bactericidal antibodies to a peptide epitope from the PorA porin of Neisseria meningitidis., PMID:17967859
Additive and synergistic bactericidal activity of antibodies directed against minor outer membrane proteins of Neisseria meningitidis., PMID:17664268
Differential capacities of outer membrane proteins from Neisseria meningitidis B to prime the murine immune system after vaccination., PMID:17212760
Immunogenicity and safety of three doses of a bivalent (B:4:p1.19,15 and B:4:p1.7-2,4) meningococcal outer membrane vesicle vaccine in healthy adolescents., PMID:17065257
Development and characterization of a murine monoclonal antibody specific for the P1.15 PorA proteins from vaccine strain B:4,7:P1.19,15 of Neisseria meningitidis., PMID:16934022
Protection by meningococcal outer membrane protein PorA-specific antibodies and a serogroup B capsular polysaccharide-specific antibody in complement-sufficient and C6-deficient infant rats., PMID:16622217
Heterologous prime-boost strategy to overcome weak immunogenicity of two serosubtypes in hexavalent Neisseria meningitidis outer membrane vesicle vaccine., PMID:16298029
Cross-linking analysis of antigenic outer membrane protein complexes of Neisseria meningitidis., PMID:16135405
Multivalent liposome-based vaccines containing different serosubtypes of PorA protein induce cross-protective bactericidal immune responses against Neisseria meningitidis., PMID:16105711
Crystal structure of an Anti-meningococcal subtype P1.4 PorA antibody provides basis for peptide-vaccine design., PMID:16038932
Protective antibody responses elicited by a meningococcal outer membrane vesicle vaccine with overexpressed genome-derived neisserial antigen 1870., PMID:16028126
Porin A-specific antibody avidity in patients who are convalescing from meningococcal B disease., PMID:15774845
PorA-specific differences in antibody avidity after vaccination with a hexavalent Men B outer membrane vesicle vaccine in toddlers and school children., PMID:15297049
PorA variable regions of Neisseria meningitidis., PMID:15200858
Activation of human dendritic cells by the PorA protein of Neisseria meningitidis., PMID:15186401
Immunogenicity and bactericidal activity in mice of an outer membrane protein vesicle vaccine against Neisseria meningitidis serogroup A disease., PMID:15149774
Recombinant meningococcal PorA protein, expressed using a vector system with potential for human vaccination, induces a bactericidal immune response., PMID:15063582
The four mouse IgG isotypes differ extensively in bactericidal and opsonophagocytic activity when reacting with the P1.16 epitope on the outer membrane PorA protein of Neisseria meningitidis., PMID:14723619
Relative immunogenicity of PorA subtypes in a multivalent Neisseria meningitidis vaccine is not dependent on presentation form., PMID:14573657
Evidence for naturally acquired T cell-mediated mucosal immunity to Neisseria meningitidis., PMID:14530350
Liposomal meningococcal B vaccination: role of dendritic cell targeting in the development of a protective immune response., PMID:12933866
Antibody specificities and effect of meningococcal carriage in icelandic teenagers receiving the Norwegian serogroup B outer membrane vesicle vaccine., PMID:12819059
Comparison of PorA VR types and porA promoter sequence from Neisseria meningitidis B isolated from non-immunised children and vaccine failures immunised with a serogroup B outer membrane protein vaccine., PMID:12798629
Cloning, sequencing and expression of immunoglobulin variable regions of murine monoclonal antibodies specific for the P1.7 and P1.16 PorA protein loops of Neisseria meningitidis., PMID:12753502
Immunogenicity of peptide-vaccine candidates predicted by molecular dynamics simulations., PMID:12729743
Serological correlates of protection against meningococci in a cohort of university students, before and during an outbreak of serogroup C infection., PMID:12717625
Cross-reactivity of antibodies against PorA after vaccination with a meningococcal B outer membrane vesicle vaccine., PMID:12654777
For research use only. Not for human or drug use.
