Catalog No.
DHJ32701
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Applications
Research Grade Biosimilar
Target
NR3A2, Nuclear receptor subfamily 3 group A member 2, ESR2, ER-beta, ESTRB, Estrogen receptor beta
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q92731
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
MC10
Clone ID
MC10
Note
For research use only. Not suitable for clinical or therapeutic use.
Progesterone withdrawal, and not increased circulating relaxin, mediates the decrease in myometrial relaxin receptor (RXFP1) expression in late gestation in rats., PMID:20686183
The anti-oestrogen fulvestrant (ICI 182,780) reduces the androgen receptor expression, ERK1/2 phosphorylation and cell proliferation in the rat ventral prostate., PMID:20874728
Gper and ESRs are expressed in rat round spermatids and mediate oestrogen-dependent rapid pathways modulating expression of cyclin B1 and Bax., PMID:20969598
Development of steroid signaling pathways during primordial follicle formation in the human fetal ovary., PMID:21430025
Oestrogen receptor polymorphisms in female patients with rheumatoid arthritis., PMID:21762042
Alteration in localization of steroid hormone receptors and coregulatory proteins in follicles from cows with induced ovarian follicular cysts., PMID:23081895
ERβ splice variant expression in four large cohorts of human breast cancer patient tumors., PMID:25007965
Estrogen and progesterone receptor subtype expression in granulosa cells from women with polycystic ovary syndrome., PMID:25603724
Germline ESR2 mutation predisposes to medullary thyroid carcinoma and causes up-regulation of RET expression., PMID:26945007
High Estrogen Receptor β Expression Is Prognostic among Adjuvant Chemotherapy-Treated Patients-Results from a Population-Based Breast Cancer Cohort., PMID:27810901
Insufficient antibody validation challenges oestrogen receptor beta research., PMID:28643774
Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis., PMID:28704378
Polymorphisms in the Estrogen Receptor Beta Gene and the Risk of Unexplained Recurrent Spontaneous Abortion., PMID:28706612
Role of FSHR rs6165 and ESR2 rs4986938 polymorphisms in ovarian stimulation of Iranian women who underwent assisted reproduction treatment., PMID:29036809
Expression of phosphorylated estrogen receptor beta is an independent negative prognostic factor for pancreatic ductal adenocarcinoma., PMID:30046904
Optimized immunohistochemical detection of estrogen receptor beta using two validated monoclonal antibodies confirms its expression in normal and malignant breast tissues., PMID:31571071
Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium., PMID:31616008
Chronic and Low Dose Exposure to Nonlyphenol or Di(2-Ethylhexyl) Phthalate Alters Cell Proliferation and the Localization of Steroid Hormone Receptors in Uterine Endometria in Mice., PMID:31660453
Applicability of Anti-Human Estrogen Receptor β Antibody PPZ0506 for the Immunodetection of Rodent Estrogen Receptor β Proteins., PMID:31847265
Neurochemical Characterization of Neurons Expressing Estrogen Receptor β in the Hypothalamic Nuclei of Rats Using in Situ Hybridization and Immunofluorescence., PMID:31877966
Missing Information from the Estrogen Receptor Puzzle: Where Are They Localized in Bull Reproductive Tissues and Spermatozoa?, PMID:31936899
A Systematic Study of the Impact of Estrogens and Selective Estrogen Receptor Modulators on Prostate Cancer Cell Proliferation., PMID:32132580
The variable association between expression and methylation of estrogen receptors and the survival of patients with different tumors., PMID:32536040
Differential distribution and potential regulatory roles of estrogen receptor 2a and 2b in the pituitary of ricefield eel Monopterus albus., PMID:32687932
Accurate assessment of estrogen receptor profiles in non-functioning pituitary adenomas using RT-digital PCR and immunohistochemistry., PMID:32926922
Optimization of immunohistochemical detection of rat ESR2 proteins with well-validated monoclonal antibody PPZ0506., PMID:33400952
Association Between Estrogen Receptors and GATA3 in Bladder Cancer: A Systematic Review and Meta-Analysis of Their Clinicopathological Significance., PMID:34690921
Antibody Validation for Estrogen Receptor Beta., PMID:35119656
IL-27 promotes decidualization via the STAT3-ESR/PGR regulatory axis., PMID:35430461
Nanobody-based RFP-dependent Cre recombinase for selective anterograde tracing in RFP-expressing transgenic animals., PMID:36114373
Optimized Mouse-on-mouse Immunohistochemical Detection of Mouse ESR2 Proteins with PPZ0506 Monoclonal Antibody., PMID:36405553
Immunohistochemical Detection of Estrogen Receptor-Beta (ERβ) with PPZ0506 Antibody in Murine Tissue: From Pitfalls to Optimization., PMID:36551855
The Co-Expression of Estrogen Receptors ERα, ERβ, and GPER in Endometrial Cancer., PMID:36769338
Immunohistochemistry for ESR2 with a Mouse Monoclonal Antibody (PPZ0506)., PMID:36823127
Transcriptome alterations in peripheral blood B cells of patients with multiple sclerosis receiving immune reconstitution therapy., PMID:37533036
Sex and interspecies differences in ESR2-expressing cell distributions in mouse and rat brains., PMID:38111056
Activation of ERβ hijacks the splicing machinery to trigger R-loop formation in triple-negative breast cancer., PMID:38513102
Estrogen receptor beta expression and role in cancers., PMID:38657699
For research use only. Not for human or drug use.
