Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Research Biosimilar

Research Grade Dupilumab

Catalog #:   DHD62601 Specific References (100) DATASHEET
Host species: Human
Isotype: IgG4-kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHD62601

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG4-kappa

Clonality

Monoclonal

Target

IL-4RA, IL-4-binding protein, IL-4 receptor subunit alpha, Soluble IL-4R-alpha, IL4-BP, IL4R, IL-4R subunit alpha, IL-4R-alpha, CD124, Interleukin-4 receptor subunit alpha, IL4RA, Soluble IL-4 receptor subunit alpha, sIL4Ralpha/prot

Concentration

6.9 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P24394

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

100 mM Pro-Ac 20mM Arg pH 5.0.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

CD124, REGN668, SAR231893, CAS: 1190264-60-8

Clone ID

Dupilumab

Data Image
  • Bioactivity
    Detects Human CD124/IL4R in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Dupilumab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma, PMID: 29782217

Dupilumab for treatment of atopic dermatitis, PMID: 29557246

Mechanisms of Dupilumab, PMID: 31505066

Dupilumab: A review of its use in the treatment of atopic dermatitis, PMID: 29471919

Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials, PMID: 31543428

Dupilumab for the treatment of asthma, PMID: 28085503

Dupilumab treatment in adults with moderate-to-severe atopic dermatitis, PMID: 25006719

Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial, PMID: 28478972

Management of dupilumab-associated conjunctivitis in atopic dermatitis, PMID: 30873757

Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis: A Phase 3 Randomized Clinical Trial, PMID: 31693077

Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma, PMID: 29782224

Efficacy and safety of dupilumab with concomitant topical corticosteroids in children 6 to 11 years old with severe atopic dermatitis: A randomized, double-blinded, placebo-controlled phase 3 trial, PMID: 32574587

Dupilumab for atopic dermatitis: evidence to date, PMID: 31210470

Dupilumab: Basic aspects and applications to allergic diseases, PMID: 32007360

Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis, PMID: 30194992

Dupilumab: A New Paradigm for the Treatment of Allergic Diseases, PMID: 29939132

Conjunctivitis in dupilumab clinical trials, PMID: 30851191

Dupilumab for prurigo nodularis: Case series and review of the literature, PMID: 31917498

Dupilumab and COVID-19: What should we expect?, PMID: 32362061

Dupilumab to Treat Type 2 Inflammatory Diseases in Children and Adolescents, PMID: 32157553

Real-world evidence of dupilumab efficacy and risk of adverse events: A systematic review and meta-analysis, PMID: 32822798

Dupilumab: A Review in Chronic Rhinosinusitis with Nasal Polyps, PMID: 32240527

Dupilumab use in dermatologic conditions beyond atopic dermatitis - a systematic review, PMID: 31693426

Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis, PMID: 31593702

Dupilumab shows long-term safety and efficacy in patients with moderate to severe atopic dermatitis enrolled in a phase 3 open-label extension study, PMID: 31374300

Dupilumab Efficacy in Patients with Uncontrolled, Moderate-to-Severe Allergic Asthma, PMID: 31521831

Dupilumab in the treatment of chronic rhinosinusitis with nasal polyposis, PMID: 32075470

Dupilumab in the treatment of asthma, PMID: 31218914

Dupilumab in persistent asthma with elevated eosinophil levels, PMID: 23688323

A Clinician's Guide to the Recognition and Management of Dupilumab-Associated Conjunctivitis, PMID: 31728936

Dupilumab (Dupixent) for Asthma, PMID: 32053330

Dupilumab treatment in moderate-to-severe atopic dermatitis: A systematic review and meta-analysis, PMID: 29472119

Dupilumab with concomitant topical corticosteroid treatment in adults with atopic dermatitis with an inadequate response or intolerance to ciclosporin A or when this treatment is medically inadvisable: a placebo-controlled, randomized phase III clinical trial (LIBERTY AD CAFÉ), PMID: 29193016

Dupilumab for the treatment of adolescents with atopic dermatitis, PMID: 32720530

Dupilumab as a novel therapy for bullous pemphigoid: A multicenter case series, PMID: 32179082

Efficacy and Safety of Multiple Dupilumab Dose Regimens After Initial Successful Treatment in Patients With Atopic Dermatitis: A Randomized Clinical Trial, PMID: 31876900

Dupilumab reduces local type 2 pro-inflammatory biomarkers in chronic rhinosinusitis with nasal polyposis, PMID: 30488542

Real-world persistence with dupilumab among adults with atopic dermatitis, PMID: 32739313

Dupilumab: Clinical Efficacy of Blocking IL-4/IL-13 Signalling in Chronic Rhinosinusitis with Nasal Polyps, PMID: 32440101

IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis, PMID: 31252032

Eye Complications During Dupilumab Treatment for Severe Atopic Dermatitis, PMID: 30653240

[Experience of using dupilumab in the treatment of severe asthma], PMID: 33346468

▼Dupilumab for atopic dermatitis, PMID: 29545264

[Key-studies on dupilumab], PMID: 30093077

Dupilumab Provides Favorable Safety and Sustained Efficacy for up to 3 Years in an Open-Label Study of Adults with Moderate-to-Severe Atopic Dermatitis, PMID: 32557382

Dupilumab for bullous pemphigoid with intractable pruritus, PMID: 32045153

A review of dupilumab in the treatment of atopic diseases, PMID: 30785362

Dupilumab for the Treatment of Recalcitrant Bullous Pemphigoid, PMID: 30140849

Treatment of Netherton Syndrome With Dupilumab, PMID: 31995125

Dupilumab, severe asthma airway responses, and SARS-CoV-2 serology, PMID: 32767400

Dupilumab Efficacy in Children With Eosinophilic Esophagitis With Prior Swallowed Topical Corticosteroid Use: A Subgroup Analysis., PMID:40531526

Psoriasis Risk in Patients With Atopic Dermatitis Treated With Dupilumab., PMID:40531497

Eosinophil and Cationic Protein Levels in Patients Treated With Dupilumab: A Real-Life Study., PMID:40530362

Leukocytoclastic Vasculitis With Eosinophilia in a Patient Receiving Dupilumab Therapy., PMID:40530217

Adverse Effects of Dupilumab for Chronic Rhinosinusitis With Nasal Polyposis: Real-World Single Institution Experience., PMID:40525458

Anti-IL-4Rα aptamer reduces IL-4 signalling and formation of nasal polyps., PMID:40524931

Four Cases of Prurigo Nodularis Requiring Nemolizumab due to Persistent Pruritus or Lesions after Dupilumab Treatment., PMID:40524402

Tape Strip Profiling of Checkpoint Inhibitor-Associated Dermatitis Highlights Pan-T-Cell Activation: A Pilot Study., PMID:40519867

[Analysis of the clinical efficacy and safety of dupilumab in the treatment of patients with moderate to severe atopic dermatitis complicated with asthma]., PMID:40518414

The Efficacy of Dupilumab in Pemphigus Vulgaris., PMID:40514796

Clinical response and remission in patients treated with dupilumab for severe asthma: Results from the nationwide Danish Severe Asthma Register., PMID:40513967

Recalcitrant Grover's disease treated with dupilumab: two long-term cases and review of the literature., PMID:40509692

Efficacy of Upadacitinib in Treating Alopecia Areata, Atopic Dermatitis, and Th1 Comorbidities in Pediatric Patients: A Comprehensive Case Series and Literature Review., PMID:40507644

Dupilumab-Induced Remission in Chronic Rhinosinusitis with Nasal Polyps and Comorbid Asthma: A 24-Month Study., PMID:40507416

Interleukin-4 and -13 Gene Expression Profiles in Immune-Related Bullous Pemphigoid Indicate Efficacy of IL-4/IL-13 Inhibitors., PMID:40507326

Dupilumab in an adolescent with eosinophilic esophagitis and eosinophilic duodenitis, a valuable treatment option., PMID:40504588

Dupilumab treatment has no effect on the nasal microbiome in patients with NSAID-exacerbated respiratory disease: a longitudinal pilot study., PMID:40503236

STAT6 gain-of-function disease: p.D519N is a new disease-causing variant that responds well to dupilumab treatment., PMID:40502541

Paradoxical Effects of Dupilumab in ABPA: Resolution of Mucus Plugging but Induction of Eosinophilic Pneumonia., PMID:40499647

Auditory and Ocular Manifestations in Pediatric Vitiligo., PMID:40498511

Dupilumab and Blood Eosinophilia: A Disease-Specific Phenomenon?, PMID:40492692

[Application and research progress of anti-IL-4α monoclonal antibody dupilumab in the treatment of type 2 asthma]., PMID:40491151

Eosinophilic esophagitis in children: new kids on the block., PMID:40490426

Aspirin-Exacerbated Respiratory Disease in the era of biologics., PMID:40490219

Drug-related visual blurring: findings from the U.S. Food and Drug Administration Adverse Event Reporting System database., PMID:40490170

Wells syndrome: emerging triggers and treatments- an updated systematic review., PMID:40488888

Effectiveness of Dupilumab Treatment in Patients With Type 2 Inflammation: A Real-Life Integrated Experience., PMID:40487737

Dupilumab-Induced Granuloma Annulare: A Challenging Adverse Effect of Atopic Dermatitis Treatment., PMID:40487493

Dupilumab Improves Histopathologic Features in Patients With Eosinophilic Esophagitis: LIBERTY EoE TREET Study Results., PMID:40487268

Advancements in Biologic Therapies for Pediatric Asthma: Emerging Therapies and Future Directions., PMID:40486460

Cost-utility analysis of sequential therapies for pediatric-onset eosinophilic esophagitis., PMID:40485534

A nationwide experience of biological treatments in children with eosinophilic esophagitis., PMID:40483369

Reply to "Considerations for enhancing dupilumab research in hypereosinophilic syndromes"., PMID:40483017

Considerations for enhancing dupilumab research in hypereosinophilic syndromes., PMID:40483016

Clinical and complete remission in patients with severe asthma with 24-month dupilumab treatment., PMID:40482373

Long-term effectiveness and safety of dupilumab in severe asthma: a 5-year real-world multicenter study., PMID:40480546

Real-World Efficacy and Safety of Dupilumab Retreatment in Adults With Relapsed Atopic Dermatitis: A Retrospective Study From China., PMID:40474541

Efficacy and glucocorticoid sparing of dupilumab in IgG4-related disease: a case series and literature review., PMID:40470558

Angiolymphoid hyperplasia with eosinophilia treated with dupilumab in a biologic-naïve patient., PMID:40466455

Effect of dupilumab for the therapy of atopic dermatitis and the effect on serum TARC, HBD2 and SEA-IgE levels and peripheral blood T helper cell subtypes., PMID:40462855

Real‑World Experience of 1 Year of Tralokinumab Treatment in Adult Patients with Atopic Dermatitis: A Single-Center Retrospective Study., PMID:40459712

Real-World Effectiveness and Safety of Dupilumab, Tralokinumab, and Upadacitinib in Patients with Atopic Dermatitis: A 52-Week International, Multicenter Retrospective Cohort Study., PMID:40459711

Dupilumab efficacy in patients with type 2 asthma and early Feno level reductions., PMID:40458676

Rapid Itch Improvement and Skin Clearance with Upadacitinib Versus Placebo (Measure Up 1 and Measure Up 2) and Versus Dupilumab (Heads Up): Results from Three Phase 3 Clinical Trials in Patients with Moderate-to-Severe Atopic Dermatitis., PMID:40457140

An unbiased tissue transcriptome analysis identifies potential markers for skin phenotypes and therapeutic responses in atopic dermatitis., PMID:40456762

[Not Available]., PMID:40456219

[Not Available]., PMID:40456218

Dupilumab Treatment Is Associated With Clinical Improvement and a Shift Toward a Health-Associated Nasal Passage Microbiota in Diffuse Type 2 Chronic Rhinosinusitis., PMID:40452334

Infectious complications of atopic dermatitis, an update., PMID:40447099

[Translated article] Exploring New Horizons in Allergic Contact Dermatitis Treatment: The Role of Emerging Therapies., PMID:40446917

Datasheet

Document Download

Research Grade Dupilumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Research Grade Dupilumab [DHD62601]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only