Anti-NFKBIE Polyclonal Antibody

Catalog No.

PHA06001

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human NFKBIE (Arg207-Pro440).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

IkB-E,IKBE,IkappaBepsilon,I-kappa-B-epsilon,IkB-epsilon,NFKBIE,NF-kappa-B inhibitor epsilon,NF-kappa-BIE

Purification

Purified by antigen affinity column.

Accession

O00221

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Assessment of genetic polymorphisms within nuclear factor-κB signaling pathway genes in rheumatoid arthritis: Evidence for replication and genetic interaction., PMID:34464884

RTEC-intrinsic IL-17-driven inflammatory circuit amplifies antibody-induced glomerulonephritis and is constrained by Regnase-1., PMID:34236049

Clinical significance of TP53, BIRC3, ATM and MAPK-ERK genes in chronic lymphocytic leukaemia: data from the randomised UK LRF CLL4 trial., PMID:32015491

Exploratory plasma proteomic analysis in a randomized crossover trial of aspirin among healthy men and women., PMID:28542447

Functional importance of stripping in NFκB signaling revealed by a stripping-impaired IκBα mutant., PMID:28167786

Improving gastric cancer preclinical studies using diverse in vitro and in vivo model systems., PMID:26955870

Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations., PMID:26675346

Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas., PMID:26647218

Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia., PMID:25987724

Acquired initiating mutations in early hematopoietic cells of CLL patients., PMID:24920063

PADI4 and HLA-DRB1 are genetic risks for radiographic progression in RA patients, independent of ACPA status: results from the IORRA cohort study., PMID:23577190

Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon., PMID:16769727

Reductions in I kappa B epsilon and changes in NF-kappa B activity during B lymphocyte differentiation., PMID:15634922

IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival., PMID:14665694

IkappaBepsilon-deficient mice: reduction of one T cell precursor subspecies and enhanced Ig isotype switching and cytokine synthesis., PMID:10570287

Constitutive nuclear translocation of NF-kappa B in B cells in the absence of I kappa B degradation., PMID:10384125

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