Catalog No.
YHG38201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu896-Phe1176
Predicted molecular weight
35.28 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13045
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FLIL, Protein flightless-1 homolog, FLII
Unveiling Genetic Markers for Milk Yield in Xinjiang Donkeys: A Genome-Wide Association Study and Kompetitive Allele-Specific PCR-Based Approach., PMID:40243566
Significance of Gelsolin Superfamily Genes in Diagnosis, Prognosis and Immune Microenvironment Regulation for Endometrial Cancer., PMID:39964147
MST1 interactomes profiling across cell death in esophageal squamous cell carcinoma., PMID:39664081
Chlamydia trachomatis Inc Ct226 is vital for FLI1 and LRRF1 recruitment to the chlamydial inclusion., PMID:39404459
A transient transcriptional activation governs unpolarized-to-polarized morphogenesis during embryo implantation., PMID:38955180
Druggability Analysis of Protein Targets for Drug Discovery to Combat Listeria monocytogenes., PMID:38930455
Nucleoredoxin Redox Interactions Are Sensitized by Aging and Potentiated by Chronic Alcohol Consumption in the Mouse Liver., PMID:38539791
FliH and FliI help FlhA bring strict order to flagellar protein export in Salmonella., PMID:38531947
Integrated analysis reveals FLI1 regulates the tumor immune microenvironment via its cell-type-specific expression and transcriptional regulation of distinct target genes of immune cells in breast cancer., PMID:38448802
Helicobacter pylori FlgN binds its substrate FlgK and the flagellum ATPase FliI in a similar manner observed for the FliT chaperone., PMID:38151822
Enhanced ileum function in weaned piglets via Laminaria digitata and alginate lyase dietary inclusion: A combined proteomics and metabolomics analysis., PMID:37775079
FLII Modulates the Myogenic Differentiation of Progenitor Cells via Actin Remodeling-Mediated YAP1 Regulation., PMID:37762638
Biallelic variants in FLII cause pediatric cardiomyopathy by disrupting cardiomyocyte cell adhesion and myofibril organization., PMID:37561591
USF1-mediated ALKBH5 stabilizes FLII mRNA in an m6A-YTHDF2-dependent manner to repress glycolytic activity in prostate adenocarcinoma., PMID:37493109
A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells., PMID:37225719
Stress-induced pseudokinase TRB3 augments IL1β signaling by interacting with Flightless homolog 1., PMID:37172723
A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy., PMID:37126682
Identification of Mir-182-3p/FLI-1 Axis as a Key Signaling in Immune Response in Cervical Cancer: A Comprehensive Bioinformatic Analysis., PMID:37047006
Global-feature of autoimmune glomerulonephritis using proteomic analysis of laser capture microdissected glomeruli., PMID:37033921
A multi-omic approach identifies an autism spectrum disorder (ASD) regulatory complex of functional epimutations in placentas from children born preterm., PMID:36938998
SENP7 deSUMOylase-governed transcriptional program coordinates sarcomere assembly and is targeted in muscle atrophy., PMID:36417853
Flightless I Negatively Regulates Macrophage Surface TLR4, Delays Early Inflammation, and Impedes Wound Healing., PMID:35883634
Comparative genomics analysis and virulence-related factors in novel Aliarcobacter faecis and Aliarcobacter lanthieri species identified as potential opportunistic pathogens., PMID:35761183
Insight Into Distinct Functional Roles of the Flagellar ATPase Complex for Flagellar Assembly in Salmonella., PMID:35602071
Is Nucleoredoxin a Master Regulator of Cellular Redox Homeostasis? Its Implication in Different Pathologies., PMID:35453355
Increased Expression of Flightless I in Cutaneous Squamous Cell Carcinoma Affects Wnt/β-Catenin Signaling Pathway., PMID:34948000
FLII and MLL1 Cooperatively Regulate Aryl Hydrocarbon Receptor-Mediated Transcription in ARPE-19 Cells., PMID:34698116
Identification of in vivo expressed proteins in live attenuated lipopolysaccharide mutant that mediates heterologous protection against Leptospira spp., PMID:34509026
Overexpression of Flii during Murine Embryonic Development Increases Symmetrical Division of Epidermal Progenitor Cells., PMID:34361001
TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma., PMID:34329586
Expression of Friend Leukemia Integration-1 (Fli-1) and the Apoptosis Regulator B Cell Lymphoma-2 (BCL-2) in Gastric Carcinoma; an Immunohistochemical Study., PMID:34314292
Membrane voltage-dependent activation mechanism of the bacterial flagellar protein export apparatus., PMID:34035173
Flightless I Homolog Reverses Enzalutamide Resistance through PD-L1-Mediated Immune Evasion in Prostate Cancer., PMID:34011528
Flagellar export apparatus and ATP synthetase: Homology evidenced by synteny predating the Last Universal Common Ancestor., PMID:33998015
A positive charge region of Salmonella FliI is required for ATPase formation and efficient flagellar protein export., PMID:33846530
The FlgN chaperone activates the Na+-driven engine of the Salmonella flagellar protein export apparatus., PMID:33712678
Generation of a new immortalized human lung pericyte cell line: a promising tool for human lung pericyte studies., PMID:33446892
Functional divergence of flagellar type III secretion system: A case study in a non-flagellated, predatory bacterium., PMID:33294133
Flightless-I is a potential biomarker for the early detection of alcoholic liver disease., PMID:33166508
The actin polymerization factor Diaphanous and the actin severing protein Flightless I collaborate to regulate sarcomere size., PMID:32980309
Categorized Genetic Analysis in Childhood-Onset Cardiomyopathy., PMID:32870709
Increasing the level of cytoskeletal protein Flightless I reduces adhesion formation in a murine digital flexor tendon model., PMID:32854733
Attenuation of Flightless I Increases Human Pericyte Proliferation, Migration and Angiogenic Functions and Improves Healing in Murine Diabetic Wounds., PMID:32764293
Landscape of in vivo Fitness-Associated Genes of Enterobacter cloacae Complex., PMID:32754144
Indole signaling decreases biofilm formation and related virulence of Listeria monocytogenes., PMID:32658271
Role of the small GTPase activating protein IQGAP1 in collagen phagocytosis., PMID:32643295
Novel Noncompetitive Type Three Secretion System ATPase Inhibitors Shut Down Shigella Effector Secretion., PMID:32567308
Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease., PMID:32524749
Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca2+ homeostasis., PMID:32504039
Flightless anchors IQGAP1 and R-ras to mediate cell extension formation and matrix remodeling., PMID:32432944
For research use only. Not for human or drug use.
