Catalog No.
YHG39201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn923-Val1148
Predicted molecular weight
28.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13075
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BIRC1, Baculoviral IAP repeat-containing protein 1, Neuronal apoptosis inhibitory protein, NAIP
NLRP11 is required for canonical NLRP3 and non-canonical inflammasome activation during human macrophage infection with mycobacteria., PMID:40272180
Uncovering the Causal Link Between Obesity-Associated Genes and Multiple Sclerosis: A Systematic Literature Review., PMID:40195065
Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages., PMID:40162563
Pyroptosis of pulmonary fibroblasts and macrophages through NLRC4 inflammasome leads to acute respiratory failure., PMID:40158217
Long-read sequencing identifies copy-specific markers of SMN gene conversion in spinal muscular atrophy., PMID:40119448
Correlation Between Neuronal Apoptosis Inhibitory Protein (NAIP), SMN2, and SMA Phenotypes: A Tertiary Care Centre Experience From India., PMID:40099840
Enteric tuft cell inflammasome activation drives NKp46+ILC3 IL22 via PGD2 and inhibits Salmonella., PMID:40079814
FlaA N/C attenuates radiation-induced lung injury by promoting NAIP/NLRC4/ASC inflammasome autophagy and inhibiting pyroptosis., PMID:40016828
T3SS translocon induces pyroptosis by direct interaction with NLRC4/NAIP inflammasome., PMID:39951384
Comprehensive copy number analysis of spinal muscular atrophy among the Iranian population., PMID:39622884
TLR priming licenses NAIP inflammasome activation by immunoevasive ligands., PMID:39556752
Molecular mechanisms of emerging inflammasome complexes and their activation and signaling in inflammation and pyroptosis., PMID:39351983
Molecular analysis of SMN2, NAIP, and GTF2H2 gene deletions and relationships with clinical subtypes of spinal muscular atrophy., PMID:39321203
Association among biomarkers, phenotypes, and motor milestones in Chinese patients with 5q spinal muscular atrophy types 1-3., PMID:39286802
NLRC4, inflammation and colorectal cancer (Review)., PMID:39239759
Atg16l2 augments Nlrc4 inflammasome activation by facilitating NAIPs-NLRC4 association., PMID:39175123
EZH2-H3K27me3-Mediated Epigenetic Silencing of DKK1 Induces Nucleus Pulposus Cell Pyroptosis in Intervertebral Disc Degeneration by Activating NLRP3 and NAIP/NLRC4., PMID:39052181
Effects of early pregnancy on NOD-like receptor expression in the ovine endometrium., PMID:38903689
Dental Pulp Stem Cells Modulate Inflammasome Pathway and Collagen Deposition of Dermal Fibroblasts., PMID:38786058
Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution., PMID:38684033
Genetic determinants of plasma protein levels in the Estonian population., PMID:38565889
NAIP Gene Deletion and SMN2 Copy Number as Molecular Tools in Predicting the Severity of Spinal Muscular Atrophy., PMID:38388850
Mechanistic insights from inflammasome structures., PMID:38374299
Study on pyroptosis-related genes Casp8, Gsdmd and Trem2 in mice with cerebral infarction., PMID:38348100
Regulation of virulence in Chromobacterium violaceum and strategies to combat it., PMID:38328423
Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing., PMID:38177670
Screening of novel tumor-associated antigens for lung adenocarcinoma mRNA vaccine development based on pyroptosis phenotype genes., PMID:38166691
NAIP/NLRC4 inflammasome participates in macrophage responses to Trypanosoma cruzi by a mechanism that relies on cathepsin-dependent caspase-1 cleavage., PMID:38124741
Structural basis for flagellin-induced NAIP5 activation., PMID:38055825
New insights into the genetic predisposition of brucellosis and its effect on the gut and vaginal microbiota in goats., PMID:37973848
Analysis, validation, and discussion of key genes in placenta of patients with gestational diabetes mellitus., PMID:37873933
Comprehensive analysis of prognostic value and immune infiltration of IAPs family in hepatocellular carcinoma., PMID:37781078
Deletions of SMNI gene exon 7 and NAIP gene exon 5 in spinal muscular atrophy patients in selected population., PMID:37750622
Protocol for reconstitution of oligomeric assembly of NAIP5-NLRC4 inflammasome in vitro., PMID:37733592
Targeting Desulfovibrio vulgaris flagellin-induced NAIP/NLRC4 inflammasome activation in macrophages attenuates ulcerative colitis., PMID:37586642
Quantifying Cell Death Induced by the NLRC4 Inflammasome., PMID:37578724
Canonical Inflammasomes., PMID:37578712
Pan-cancer analysis of the intervertebral-disc-degeneration-related innate immunity gene NAIP., PMID:37267294
A 360° view of the inflammasome: Mechanisms of activation, cell death, and diseases., PMID:37236155
Changes in expression levels of Nod-like receptors in the spleen of ewes., PMID:37228386
TLR priming licenses NAIP inflammasome activation by immunoevasive ligands., PMID:37205371
Elevated expression of the AIM2 gene in response to Helicobacter pylori along with the decrease of NLRC4 inflammasome is associated with peptic ulcer development., PMID:37170445
Human and mouse NAIP/NLRC4 inflammasome responses to bacterial infection., PMID:37058933
Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity., PMID:36948192
A comprehensive overview of SMN and NAIP copy numbers in Iranian SMA patients., PMID:36828874
Diagnostic and predictive values of pyroptosis-related genes in sepsis., PMID:36817458
The First Report of Iranian Registry of Patients with Spinal Muscular Atrophy., PMID:36776076
Influence of Perinatal Factors on Gene Expression of IAPs Family and Main Factors of Pluripotency: OCT4 and SOX2 in Human Breast Milk Stem Cells-A Preliminary Report., PMID:36768802
Genetic and Epigenetic Regulation of the Innate Immune Response to Gout., PMID:36745138
Mechanism of NAIP-NLRC4 inflammasome activation revealed by cryo-EM structure of unliganded NAIP5., PMID:36604500
For research use only. Not for human or drug use.
