Catalog No.
YHG05001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro404-Ser591
Predicted molecular weight
23.87 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q05513
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PKC2, nPKC-zeta, PRKCZ, Protein kinase C zeta type
Persistently increased expression of PKMζ and unbiased gene expression profiles identify hippocampal molecular traces of a long-term active place avoidance memory and 'shadow' proteins., PMID:40502027
A multi-omics exploration of PPARG activation in colon cancer: kinases featuring a PPRE sequence within regulatory regions., PMID:40500799
A high-fructose diet leads to osteoporosis by suppressing the expression of Thrb and facilitating the accumulation of cholesterol., PMID:40204733
DNA Methyltransferases 1-Regulated Methylation of Protein Kinase C Zeta Influences Its Expression in Breast Cancer Cells., PMID:40133985
Discovery and Functional Characterization of a Recombinant Fragment of Human Collagen Type XVII., PMID:40066849
Systematic druggable genome-wide Mendelian randomization to identify therapeutic targets and dominant flora for ulcerative colitis., PMID:39978659
Unveiling the substantial role of rutin in the management of drug-induced nephropathy using network pharmacology and molecular docking., PMID:39733639
Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse., PMID:39650797
Investigation and validation of neurotransmitter receptor-related biomarkers for forecasting clinical outcomes and immunotherapeutic efficacy in breast cancer., PMID:39615806
Comprehensive Characterization of Anti-HLA and Non-HLA Antibodies in Patients on Kidney Transplant Waiting List and Evaluation of Their Impact on Alloimmunization Risk and Dialysis Treatment., PMID:39596170
Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse., PMID:39484575
Identification of the effects of hypoxia on the liver tissues of Nile tilapia Oreochromis Niloticus., PMID:39379813
Genetic polymorphism in untranslated regions of PRKCZ influences mRNA structure, stability and binding sites., PMID:39272077
Prenatal opioid exposure significantly impacts placental protein kinase C (PKC) and drug transporters, leading to drug resistance and neonatal opioid withdrawal syndrome., PMID:39238930
Genome-wide DNA methylation profiling in blood reveals epigenetic signature of incident acute coronary syndrome., PMID:39198424
Kinome expression profiling improves risk stratification and therapeutic targeting in myelodysplastic syndromes., PMID:38527292
Development of Genetically Encoded Fluorescent KSR1-Based Probes to Track Ceramides during Phagocytosis., PMID:38474242
Intestinal mRNA expression analysis of polarity-related genes identified the discriminatory ability of CRB3 as a diagnostic marker for celiac disease., PMID:38353316
Different Transcriptome Features of Peripheral Blood Mononuclear Cells in Non-Emphysematous Chronic Obstructive Pulmonary Disease., PMID:38203236
Comprehensive Analysis of lncRNA and mRNA Expression Profile of Macrophage RAW264.7 Stimulated by Antimicrobial Peptide BSN-37., PMID:37587823
Bioinformatic platforms for clinical stratification of natural history of atherosclerotic cardiovascular diseases., PMID:37562936
Screening for diagnostic targets in tuberculosis and study on its pathogenic mechanism based on mRNA sequencing technology and miRNA-mRNA-pathway regulatory network., PMID:36793717
Identification of Epigenetically Regulated Genes Distinguishing Intracranial from Extracranial Melanoma Metastases., PMID:36716920
DNA methylation of the promoter region at the CREB1 binding site is a mechanism for the epigenetic regulation of brain-specific PKMζ., PMID:36682583
Human Proteome Microarray identifies autoantibodies to tumor-associated antigens as serological biomarkers for the diagnosis of hepatocellular carcinoma., PMID:36587394
Effects of Triiodothyronine on Human Osteoblast-Like Cells: Novel Insights From a Global Transcriptome Analysis., PMID:35784485
Differential Expression of the Genes Coding for Adipokines and Epithelial Cell Polarity Components in Women With Low and High Mammographic Density., PMID:35725805
The mechanism and effects of remdesivir-induced developmental toxicity in zebrafish: Blood flow dysfunction and behavioral alterations., PMID:35560222
Identification of Prognostic Biomarkers for Bladder Cancer Based on DNA Methylation Profile., PMID:35174173
Pan-Cancer Study on Protein Kinase C Family as a Potential Biomarker for the Tumors Immune Landscape and the Response to Immunotherapy., PMID:35174160
Methylation-mediated silencing of protein kinase C zeta induces apoptosis avoidance through ATM/CHK2 inactivation in dedifferentiated chondrosarcoma., PMID:35017658
An epigenome-wide DNA methylation study of patients with COVID-19., PMID:34185889
ABCA1, TCF7, NFATC1, PRKCZ, and PDGFA DNA methylation as potential epigenetic-sensitive targets in acute coronary syndrome via network analysis., PMID:34151742
Transcriptome analysis reveals key genes and pathways associated with piglet fetal mummification., PMID:34139142
The miR-223/nuclear factor I-A axis regulates inflammation and cellular functions in intestinal tissues with necrotizing enterocolitis., PMID:33932136
Cell lineage-specific methylome and genome alterations in gout., PMID:33493135
DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4 + T cells in response to SIV infections., PMID:33298174
Inverse Correlation of TRIM32 and Protein Kinase C ζ in T Helper Type 2-Biased Inflammation., PMID:33096083
Hydroxyurea Scavenges Free Radicals and Induces the Expression of Antioxidant Genes in Human Cell Cultures Treated With Hemin., PMID:32765515
Alterations in DNA methylation profiles in cancellous bone of postmenopausal women with osteoporosis., PMID:32496000
aPKC in neuronal differentiation, maturation and function., PMID:32269838
Identification of 34 genes conferring genetic and pharmacological risk for the comorbidity of schizophrenia and smoking behaviors., PMID:32012119
Protein-protein interactions underlying the behavioral and psychological symptoms of dementia (BPSD) and Alzheimer's disease., PMID:31951614
PRKCZ-AS1 promotes the tumorigenesis of lung adenocarcinoma via sponging miR-766-5p to modulate MAPK1., PMID:31939714
Pancreastatin inhibitor, PSTi8 ameliorates metabolic health by modulating AKT/GSK-3β and PKCλ/ζ/SREBP1c pathways in high fat diet induced insulin resistance in peri-/post-menopausal rats., PMID:31473204
Clinical significance of atypical protein kinase C (PKCι and PKCζ) and its relationship with yes-associated protein in lung adenocarcinoma., PMID:31412817
MicroRNAs and their target mRNAs as potential biomarkers among smokers and non-smokers with lung adenocarcinoma., PMID:33444474
Histone acetylation determines transcription of atypical protein kinases in rat neurons., PMID:30867503
Histone Acetylation of Immune Regulatory Genes in Human Placenta in Association with Maternal Intake of Olive Oil and Fish Consumption., PMID:30823645
Dysregulation of miR-431 and target gene FOXA1 in intestinal tissues of infants with necrotizing enterocolitis., PMID:30624964