Catalog No.
YHF64701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg90-Gln152
Predicted molecular weight
20.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P78337
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hindlimb-expressed homeobox protein backfoot, Paired-like homeodomain transcription factor 1, Homeobox protein PITX1, PITX1, PTX1, BFT, Pituitary homeobox 1
Molecular insights into region-specific sexual dichromatism: Comparative transcriptome analysis of red cheek pigmentation in zebra finches., PMID:40354322
The transcription factor PITX1 cooperates with super-enhancers to regulate the expression of DUSP4 and inhibit pyroptosis in pulmonary artery smooth muscle cells., PMID:40241046
Human and bacterial genetic variation shape oral microbiomes and health., PMID:40236410
The Supportive Role of Lymph Node Mesenchymal Stromal Cells in Follicular Lymphoma Involves the PITX1-hTERT-Podoplanin Axis., PMID:40130551
Seven Hub Genes Associated with Huntington's Disease and Diagnostic and Therapeutic Potentials Identified by Computational Biology., PMID:40059764
Transcriptome analysis of muscle atrophy in Leizhou black goats: identification of key genes and insights into limb-girdle muscular dystrophy., PMID:39871147
Functional study of three cases with novel TBX19 variants., PMID:39776042
Modeling corticotroph deficiency with pituitary organoids supports the functional role of NFKB2 in human pituitary differentiation., PMID:39607428
Reprogramming of epidermal keratinocytes by PITX1 transforms the cutaneous cellular landscape and promotes wound healing., PMID:39480496
Eicosatrienoic acid inhibits estradiol synthesis through the CD36/FOXO1/CYP19A1 signaling pathway to improve PCOS in mice., PMID:39236935
Circ-PITX1 promotes non-small-cell lung cancer progression through regulating ETS1 expression via miR-615-5p., PMID:39138880
The Megacomplex protects ER-alpha from degradation by Fulvestrant in epithelial ovarian cancer., PMID:39048045
A novel homozygous FAM92A gene (CIBAR1) variant further confirms its association with non-syndromic postaxial polydactyly type A9 (PAPA9)., PMID:38853702
Identification of common genes and pathways between type 2 diabetes and COVID-19., PMID:38699234
Exome sequencing of 1190 non-syndromic clubfoot cases reveals HOXD12 as a novel disease gene., PMID:38663984
Exosomal miRNA Changes Associated with Restoration to Sinus Rhythm in Atrial Fibrillation Patients., PMID:38612670
Sall genes regulate hindlimb initiation in mouse embryos., PMID:38386912
Boundary stacking interactions enable cross-TAD enhancer-promoter communication during limb development., PMID:38238628
The single-cell transcriptomic atlas and RORA-mediated 3D epigenomic remodeling in driving corneal epithelial differentiation., PMID:38177186
COL1A1 regulates the apoptosis of embryonic stem cells by mediating the PITX1/TBX4 signaling., PMID:38158794
Rewiring of the promoter-enhancer interactome and regulatory landscape in glioblastoma orchestrates gene expression underlying neurogliomal synaptic communication., PMID:37833281
Therapeutic response to pazopanib: case report and literature review on molecular abnormalities of aggressive prolactinomas., PMID:37529607
De novo human brain enhancers created by single-nucleotide mutations., PMID:36791193
Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging., PMID:36640359
What Is the Exact Contribution of PITX1 and TBX4 Genes in Clubfoot Development? An Italian Study., PMID:36360195
PITX1 suppresses osteosarcoma metastasis through exosomal LINC00662-mediated M2 macrophage polarization., PMID:36334221
The expression and methylation of PITX genes is associated with the prognosis of head and neck squamous cell carcinoma., PMID:36204311
A novel homozygous variant in the GLI1 underlies postaxial polydactyly in a large consanguineous family with intra familial variable phenotypes., PMID:36067927
Serum Proteins, HMMR, NXPH4, PITX1 and THBS4; A Panel of Biomarkers for Early Diagnosis of Hepatocellular Carcinoma., PMID:35456219
Distinct regulatory states control the elongation of individual skeletal rods in the sea urchin embryo., PMID:35403290
PITX1 Is a Regulator of TERT Expression in Prostate Cancer with Prognostic Power., PMID:35267575
Divergence of Tbx4 hindlimb enhancer HLEA underlies the hindlimb loss during cetacean evolution., PMID:35134498
The circ-PITX1 promotes non-small cell lung cancer development via the miR-30e-5p/ITGA6 axis., PMID:35007184
Cell-specific alterations in Pitx1 regulatory landscape activation caused by the loss of a single enhancer., PMID:34903763
Upregulated Transcription Factor PITX1 Predicts Poor Prognosis in Kidney Renal Clear Cell Carcinoma-Based Bioinformatic Analysis and Experimental Verification., PMID:34868397
MLL1 is required for maintenance of intestinal stem cells., PMID:34860830
Genotype-phenotype correlation in clubfoot (talipes equinovarus)., PMID:34782442
Functional screen of inflammatory bowel disease genes reveals key epithelial functions., PMID:34758847
A Novel Homozygous Missense Mutation in the Zinc Finger DNA Binding Domain of GLI1 Causes Recessive Post-Axial Polydactyly., PMID:34721536
PITX1 inhibits the growth and proliferation of melanoma cells through regulation of SOX family genes., PMID:34526609
Tbx4 function during hindlimb development reveals a mechanism that explains the origins of proximal limb defects., PMID:34423345
A Polymer Physics Model to Dissect Genome Organization in Healthy and Pathological Phenotypes., PMID:34415543
Differential gene expression identifies a transcriptional regulatory network involving ER-alpha and PITX1 in invasive epithelial ovarian cancer., PMID:34215221
Curcumin-Alleviated Osteoarthritic Progression in Rats Fed a High-Fat Diet by Inhibiting Apoptosis and Activating Autophagy via Modulation of MicroRNA-34a., PMID:34103964
Lateral rectus muscle differentiation potential in paralytic esotropia patients., PMID:34044792
Immunity-longevity tradeoff neurally controlled by GABAergic transcription factor PITX1/UNC-30., PMID:34038721
Analysis of genes regulated by DUX4 via oxidative stress reveals potential therapeutic targets for treatment of facioscapulohumeral dystrophy., PMID:34030118
Prognostic Signature for Lung Adenocarcinoma Patients Based on Cell-Cycle-Related Genes., PMID:33869220
Multi-omic profiling of pituitary thyrotropic cells and progenitors., PMID:33858413
Pitx genes in development and disease., PMID:33844046
For research use only. Not for human or drug use.
