Catalog No.
YHF61701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp156-Gly368
Predicted molecular weight
26.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P68032
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ACTC, Actin, alpha cardiac muscle 1, Alpha-cardiac actin, ACTC1
ACTC1 Variants Result in Isolated and Syndromic Cardiac Phenotypes., PMID:40421724
Computational simulations aided prioritization of genomic targets for congenital heart disease (CHD) against developmental toxicity., PMID:40334872
Fuling Wenxin formula treats "Qi-Yin deficiency" arrhythmia by regulating the dilated cardiomyopathy and adrenergic signaling pathway in cardiomyocytes., PMID:40319835
Clinical Features and Prospective Outcomes of Thin-Filament Hypertrophic Cardiomyopathy: Intrinsic Data and Comparative Insights from Other Cohorts., PMID:39941537
Effects of in vitro cytochalasin D and hypoxia on mitochondrial energetics and biogenesis, cell signal status and actin/tubulin/Hsp/MMP entity in air-breathing fish heart., PMID:39864717
Exploring markers in nursing care of prostate cancer., PMID:39854742
A De Novo Mutation in ACTC1 and a TTN Variant Linked to a Severe Sporadic Infant Dilated Cardiomyopathy Case., PMID:39759977
Potential Biomarkers in Myocardial Fibrosis: A Bioinformatic Analysis., PMID:39699450
Role of immune-related endoplasmic reticulum stress genes in sepsis-induced cardiomyopathy: Novel insights from bioinformatics analysis., PMID:39671358
Searching for genetic determinants for left ventricular non-compaction., PMID:39429584
Exploring the predictive values of SERP4 and FRZB in dilated cardiomyopathy based on an integrated analysis., PMID:39425025
A Cautionary Tale of Hypertrophic Cardiomyopathy-From "Benign" Left Ventricular Hypertrophy to Stroke, Atrial Fibrillation, and Molecular Genetic Diagnostics: A Case Report and Review of Literature., PMID:39273332
Proteomic and secretomic comparison of young and aged dermal fibroblasts highlights cytoskeleton as a key component during aging., PMID:39197170
Feline hypertrophic cardiomyopathy: Does the microRNA-mRNA regulatory network contribute to heart sarcomeric protein remodelling?, PMID:39138588
Human Genetics of Ventricular Septal Defect., PMID:38884729
Molecular Pathways and Animal Models of Atrial Septal Defect., PMID:38884727
Human Genetics of Atrial Septal Defect., PMID:38884726
The Role of the MYL4 Gene in Porcine Muscle Development and Its Molecular Regulatory Mechanisms., PMID:38731374
Identification of different myofiber types in pigs muscles and construction of regulatory networks., PMID:38658807
Comprehensive Analysis of Key Endoplasmic Reticulum Stress-Related Genes and Immune Infiltrates in Stanford Type A Aortic Dissection., PMID:38445624
Deciphering the omicron variant: integrated omics analysis reveals critical biomarkers and pathophysiological pathways., PMID:38424541
Influence of a Passive Tilt Test on the Proteomic Composition of the Blood of Healthy Humans., PMID:38342807
Extracellular vesicles (EVs): A promising therapeutic tool in the heart tissue regeneration., PMID:38131134
Regenerating human skeletal muscle forms an emerging niche in vivo to support PAX7 cells., PMID:37919520
Knockout of M-LP/Mpv17L, a newly identified atypical PDE, induces physiological afferent cardiac hypertrophy in mice., PMID:37851308
[Clinical and genetic analysis of eight children with Primary hypertrophic cardiomyopathy]., PMID:37730219
Prinzmetal angina in a child with actin gene ACTC1 mutation., PMID:37489518
The Definition of Sarcomeric and Non-Sarcomeric Gene Mutations in Hypertrophic Cardiomyopathy Patients: A Multicenter Diagnostic Study Across Türkiye., PMID:37466024
Variants in ACTC1 underlie distal arthrogryposis accompanied by congenital heart defects., PMID:37457373
Novel immune cell infiltration-related biomarkers in atherosclerosis diagnosis., PMID:37151293
Description of a Novel Cardiac Phenotype Associated With a Missense Variant in the Cardiac α-Actin (ACTC1) Gene., PMID:36960733
Variants in ACTC1 underlie distal arthrogryposis accompanied by congenital heart defects., PMID:36945405
Exogenous Hydrogen Sulfide Mitigates Oxidative Stress and Mitochondrial Damages Induced by Polystyrene Microplastics in Osteoblastic Cells of Mice., PMID:36860583
Identification and Functional Prediction of Long Non-Coding RNA in Longissimus Dorsi Muscle of Queshan Black and Large White Pigs., PMID:36672938
Ferroptosis-related ACSL3 and ACTC1 predict metastasis-free survival for prostate cancer patients undergoing radical radiotherapy., PMID:36577584
Conventional Ameloblastoma. A Case Report with Microarray and Bioinformatic Analysis., PMID:36553196
Scalable Generation of Nanovesicles from Human-Induced Pluripotent Stem Cells for Cardiac Repair., PMID:36430812
KLF13 Loss-of-Function Mutations Underlying Familial Dilated Cardiomyopathy., PMID:36346048
The tumor microenvironment and prognostic role of autophagy- and immune-related genes in bladder cancer., PMID:36245371
Thin filament cardiomyopathies: A review of genetics, disease mechanisms, and emerging therapeutics., PMID:36158814
CDH1 overexpression predicts bladder cancer from early stage and inversely correlates with immune infiltration., PMID:36131343
Puerarin ameliorates myocardial remodeling of spontaneously hypertensive rats through inhibiting TRPC6-CaN-NFATc3 pathway., PMID:36087696
Overexpression of PYGO1 promotes early cardiac lineage development in human umbilical cord mesenchymal stromal/stem cells by activating the Wnt/β-catenin pathway., PMID:36085540
Mutational Assessment in NKX2-5 and ACTC1 Genes in Patients with Congenital Cardiac Septal Defect (CCSD) from Ethnic Kashmiri Population., PMID:36011517
Alpha-cardiac Actin Serum Expression Levels Detect Acute Cellular Rejection in Heart Transplant Patients., PMID:35939381
Genetic Profile of Left Ventricular Noncompaction Cardiomyopathy in Children-A Single Reference Center Experience., PMID:35893073
Identification of Ferroptosis-Associated Genes in Prostate Cancer by Bioinformatics Analysis., PMID:35860472
Proteomic Profiling of Small Extracellular Vesicles Isolated from the Plasma of Vietnamese Patients with Non-Small Cell Lung Cancer Reveals Some Potential Biomarkers., PMID:35763629