Catalog No.
YHF55601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val2-Glu165
Predicted molecular weight
20.19 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P62937
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PPIase A, Cyclosporin A-binding protein, Peptidyl-prolyl cis-trans isomerase A, Cyclophilin A, PPIA, CYPA, Rotamase A
Identification of Key Genes and Potential Therapeutic Targets in Sepsis-Associated Acute Kidney Injury Using Transformer and Machine Learning Approaches., PMID:40428155
In Silico Targeting and Immunological Profiling of PpiA in Mycobacterium tuberculosis: A Computational Approach., PMID:40333132
Cerebrospinal fluid proteome profiling across the Alzheimer's disease continuum: a step towards solving the equation for 'X'., PMID:40329321
Plasma Exosomal Proteomics Identifies Differentially Expressed Proteins as Biomarkers for Acute Myocardial Infarction., PMID:40305362
Promoting activities of human cyclophilin A on calcium oxalate stone formation at crystal growth, aggregation and crystal-cell adhesion phases., PMID:40258556
Inducing Targeted, Caspase-Independent Apoptosis with New Chimeric Proteins for Treatment of Solid Cancers., PMID:40227697
Integrating single-cell RNA sequencing, WGCNA, and machine learning to identify key biomarkers in hepatocellular carcinoma., PMID:40169794
Identifying G-quadruplex-interacting proteins in cancer-related gene promoters., PMID:40025218
Quantitative serum proteomic analysis for biomarker discovery in post-COVID-19 postural orthostatic tachycardia syndrome (PC-POTS) patients., PMID:40022872
PPIA enhances cell growth and metastasis through CD147 in oral cancer., PMID:39921142
Structural analysis of extracellular ATP-independent chaperones of streptococcal species and protein substrate interactions., PMID:39878509
Cyclophilin A Regulates Tripartite Motif 5 Alpha Restriction of HIV-1., PMID:39859212
PPIA-coExp: Discovering Context-Specific Biomarkers Based on Protein-Protein Interactions, Co-Expression Networks, and Expression Data., PMID:39684321
Global Profiling Lysine Reactivity and Ligandability with Oxidant-Triggered Bioconjugation Chemistry., PMID:39543955
Effect of Mutation Type on Ectopic Ossification Among Adult Patients With X-Linked Hypophosphatemia., PMID:39498416
Peptidylprolyl isomerase A guides SENP5/GAU1 DNA-lncRNA triplex generation for driving tumorigenesis., PMID:39433793
A Proteomic Analysis of Nasopharyngeal Carcinoma in a Moroccan Subpopulation., PMID:39409902
Integration of bioinformatics and multi-layered experimental validation reveals novel functions of acetylation-related genes in intervertebral disc degeneration., PMID:39349110
Mycobacterial peptidyl prolyl isomerase A activates STING-TBK1-IRF3 signaling to promote IFNβ release in macrophages., PMID:39288201
Evolution toward extremely high imipenem resistance in Mycobacterium abscessus outbreak strains., PMID:39254295
Impact of maternal protein restriction on the proteomic landscape of male rat lungs across the lifespan., PMID:39218056
Novel biomarkers associated with oxidative stress and immune infiltration in intervertebral disc degeneration based on bioinformatics approaches., PMID:39182249
NQO1 Triggers Neutrophil Recruitment and NET Formation to Drive Lung Metastasis of Invasive Breast Cancer., PMID:39073320
The effect of overexpression of CyPA on gene expression in human umbilical vein endothelial cells., PMID:39029007
Unveiling novel targets in melanoma under melanogenesis stimulation and photodynamic therapy by redox proteomics., PMID:38961772
Identification of a novel lactylation-related gene signature predicts the prognosis of multiple myeloma and experiment verification., PMID:38956267
PPIA dictates NRF2 stability to promote lung cancer progression., PMID:38830868
Nonperturbative Fluorogenic Labeling of Immunophilins Enables the Wash-free Detection of Immunosuppressants., PMID:38799658
Role of cyclophilin A in aggravation of myocardial ischemia reperfusion injury via regulation of apoptosis mediated by thioredoxin-interacting protein., PMID:38669522
Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing., PMID:38553595
Mice lacking cyclophilin B, but not cyclophilin A, are protected from the development of NASH in a diet and chemical-induced model., PMID:38427624
Integrated meta-analysis of colorectal cancer public proteomic datasets for biomarker discovery and validation., PMID:38252632
Reference genes for gene expression profiling in mouse models of Listeria monocytogenes infection., PMID:38112054
Screening and Identifying Reference Genes for Erythrocyte Production from Cord Blood CD34+ Cells Exposed to Hypoxia., PMID:38011643
The cyclophilin A-binding loop of the capsid regulates the human TRIM5α sensitivity of nonpandemic HIV-1., PMID:37983491
Optimal reference genes for RNA tissue analysis in small animal models of hemorrhagic fever viruses., PMID:37938597
Bioinformatics analysis and experimental validation of tumorigenic role of PPIA in gastric cancer., PMID:37926757
Recognition and reprogramming of E3 ubiquitin ligase surfaces by α-helical peptides., PMID:37914719
Insensitive Effects of Inflammatory Cytokines on the Reference Genes of Synovial Fluid Resident-Mesenchymal Stem Cells Derived from Rheumatoid Arthritis Patients., PMID:37894839
Effect of electroacupuncture intervention on the spinal cord PPIA/NF-κB signaling pathway in mice with amyotrophic lateral sclerosis., PMID:37879951
Proteomic Analysis Reveals Novel Plasma Biomarkers for Neurological Complications in Patients With Congenital Cytomegalovirus Infection., PMID:37738566
Identification of PPA1 inhibitor candidates for potential repurposing in cancer medicine., PMID:37733630
YWHAZ and TBP are potential reference gene candidates for qPCR analysis of response to radiation therapy in colorectal cancer., PMID:37558778
Induced Heteroresistance in Carbapenem-Resistant Acinetobacter baumannii (CRAB) via Exposure to Human Pleural Fluid (HPF) and Its Impact on Cefiderocol Susceptibility., PMID:37511511
Housekeeping gene expression variability in differentiating and non-differentiating 3T3-L1 cells., PMID:37436361
Identification of heat shock protein70-2 and protamine-1 mRNA, proteins, and analyses of their association with fertility using frozen-thawed sperm in Madura bulls., PMID:37402446
Development and validation of metabolic models for predicting survival and immune status of hepatocellular carcinoma patients., PMID:37166013
Cervical Fluids Are a Source of Protein Biomarkers for Early, Non-Invasive Endometrial Cancer Diagnosis., PMID:36765869
Reference gene expression stability within the rat brain under mild intermittent ketosis induced by supplementation with medium-chain triglycerides., PMID:36757952
Influence of growth parameters on bacteriocin-like inhibitory substances (BLIS) production by lactic acid bacteria., PMID:36688755