Catalog No.
YHF18101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile3-Lys194
Predicted molecular weight
24.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P56597
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
nm23-H5, Testis-specific nm23 homolog, NDK-H 5, Inhibitor of p53-induced apoptosis-beta, NME5, NDP kinase homolog 5, IPIA-beta, Nucleoside diphosphate kinase homolog 5
IQUB mutation induces radial spoke 1 deficiency causing asthenozoospermia with normal sperm morphology in humans and mice., PMID:39849482
Mitochondrial NME6: A Paradigm Change within the NME/NDP Kinase Protein Family?, PMID:39120309
Ciliary Ultrastructure Assessed by Transmission Electron Microscopy in Adults with Bronchiectasis and Suspected Primary Ciliary Dyskinesia but Inconclusive Genotype., PMID:37998386
Primary Ciliary Dyskinesia Patient-Specific hiPSC-Derived Airway Epithelium in Air-Liquid Interface Culture Recapitulates Disease Specific Phenotypes In Vitro., PMID:37296588
Combined photodynamic therapy with chloroaluminum phthalocyanine and doxorubicin nanoemulsions in breast cancer model., PMID:33845338
Generation of two hiPSC clones (MHHi019-A, MHHi019-B) from a primary ciliary dyskinesia patient carrying a homozygous deletion in the NME5 gene (c.415delA (p.Ile139Tyrfs*8))., PMID:32950024
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8., PMID:32724395
A nonsense variant in NME5 causes human primary ciliary dyskinesia with radial spoke defects., PMID:32185794
Characterization of Nme5-Like Gene/Protein from the Red Alga Chondrus Crispus., PMID:31877804
Genome-wide scans identify known and novel regions associated with prolificacy and reproduction traits in a sub-Saharan African indigenous sheep (Ovis aries)., PMID:31758253
NME5 frameshift variant in Alaskan Malamutes with primary ciliary dyskinesia., PMID:31479451
Nuclear functions of NME proteins., PMID:29058704
Regulation of Sec16 levels and dynamics links proliferation and secretion., PMID:25526736
Deregulation of purine metabolism in Alzheimer's disease., PMID:25311278
Coordinated genomic control of ciliogenesis and cell movement by RFX2., PMID:24424412
Additive effect of the AZGP1, PIP, S100A8 and UBE2C molecular biomarkers improves outcome prediction in breast carcinoma., PMID:24114735
Simultaneous modulation of the intrinsic and extrinsic pathways by simvastatin in mediating prostate cancer cell apoptosis., PMID:22974127
Transactivation of the human NME5 gene by Sp1 in pancreatic cancer cells., PMID:22564704
Identification of NME5 as a contributor to innate resistance to gemcitabine in pancreatic cancer cells., PMID:22325559
An activity model for novel antidepressants that interact with the serotonin transporter (SERT)., PMID:21919867
Nme protein family evolutionary history, a vertebrate perspective., PMID:19852809
Genes involved in differentiation, stem cell renewal, and tumorigenesis are modulated in telomerase-immortalized human urothelial cells., PMID:18644980
Nm23/NDP kinases in human male germ cells: role in spermiogenesis and sperm motility?, PMID:14499630
Cloning, sequencing, and characterization of the murine nm23-M5 gene during mouse spermatogenesis and spermiogenesis., PMID:12788088
A new human nm23 homologue (nm23-H5) specifically expressed in testis germinal cells., PMID:9742940
For research use only. Not for human or drug use.
