Catalog No.
YHF11701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu667-Asp916
Predicted molecular weight
54.05 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P55283
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
R-CAD, R-cadherin, Retinal cadherin, CDH4, Cadherin-4
ATRX ADD domain is a versatile module for recognizing macroH2A, H3, and beyond., PMID:40443347
Cadherin 4 assembles a family of color-preferring retinal circuits that respond to light offset., PMID:40081378
Classical cadherins evolutionary constraints in primates is associated with their expression in the central nervous system., PMID:39570883
Cadherin adhesion complexes direct cell aggregation in the epithelial transition of Wnt-induced nephron progenitor cells., PMID:39344436
Cytosolic Cadherin 4 promotes angiogenesis and metastasis in papillary thyroid cancer by suppressing the ubiquitination/degradation of β-catenin., PMID:38402159
Transcriptomic analysis of glucosidase II beta subunit (GluIIß) knockout A549 cells reveals its roles in regulation of cell adhesion molecules (CAMs) and anti-tumor immunity., PMID:38245670
Understanding the Role of CDH4 in Multiple System Atrophy Brain., PMID:38143373
FKBP5 deficiency attenuates calcium oxalate kidney stone formation by suppressing cell-crystal adhesion, apoptosis and macrophage M1 polarization via inhibition of NF-κB signaling., PMID:37740796
DNA Methylation Pattern in Somatotroph Pituitary Neuroendocrine Tumors., PMID:37699356
CDH4 inhibits ferroptosis in oral squamous cell carcinoma cells., PMID:37237299
Pharmacogenetics of tenofovir renal toxicity in HIV-positive Southern Africans., PMID:37099271
Alu Deletions in LAMA2 and CDH4 Genes Are Key Components of Polygenic Predictors of Longevity., PMID:36362280
Expression Profile and Prognostic Values of CDH Family Members in Lung Adenocarcinoma., PMID:35242247
Cadherin switches during epithelial-mesenchymal transition: CDH4/RCAD downregulation reduces bladder cancer progression., PMID:35064910
Identification of 4 novel human ocular coloboma genes ANK3, BMPR1B, PDGFRA, and CDH4 through evolutionary conserved vertebrate gene analysis., PMID:35034853
MicroRNA Dysregulation in the Hippocampus of Rats with Noise-Induced Hearing Loss., PMID:34527169
Systemic analysis of the expression levels and prognosis of breast cancer-related cadherins., PMID:33899544
Identification of candidate SNPs and genes associated with anti-RGNNV using GWAS in the red-spotted grouper, Epinephelus akaara., PMID:33609701
Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells., PMID:33470497
Regulatory CDH4 Genetic Variants Associate With Risk to Develop Capecitabine-Induced Hand-Foot Syndrome., PMID:32757270
Expression and Prognostic Significance of Cadherin 4 (CDH4) in Renal Cell Carcinoma., PMID:32511216
CircRNA EPB41L2 inhibits tumorigenicity of lung adenocarcinoma through regulating CDH4 by miR-211-5p., PMID:32329852
A Novel Variant Rearrangement of the Rare Aberration dic(17;20)(p11.2;q11.2) Characterized by Array-CGH as an Insertion in a Patient with Myelodysplastic Syndrome of Multilineage Dysplasia (MDS-MLD)., PMID:32018267
P-cadherin-induced decorin secretion is required for collagen fiber alignment and directional collective cell migration., PMID:31604795
Bioinformatics prediction and experimental validation of a novel microRNA: hsa-miR-B43 within human CDH4 gene with a potential metastasis-related function in breast cancer., PMID:31489987
Partially overlapping guidance pathways focus the activity of UNC-40/DCC along the anteroposterior axis of polarizing neuroblasts., PMID:31488562
Cdh4 Down-Regulation Impairs in Vivo Infiltration and Malignancy in Patients Derived Glioblastoma Cells., PMID:31426573
LncRNA-miRNA-mRNA expression variation profile in the urine of calcium oxalate stone patients., PMID:31036010
Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor., PMID:30923315
Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma., PMID:30275445
Postnatal developmental dynamics of cell type specification genes in Brn3a/Pou4f1 Retinal Ganglion Cells., PMID:29958540
The cyclin-dependent kinase inhibitor flavopiridol (alvocidib) inhibits metastasis of human osteosarcoma cells., PMID:29805751
Cadherins Interact With Synaptic Organizers to Promote Synaptic Differentiation., PMID:29760652
Comprehensive genomic analysis of patients with disorders of cerebral cortical development., PMID:29706646
CDH4 is a novel determinant of osteosarcoma tumorigenesis and metastasis., PMID:29610525
Systematic genetic analyses of genome-wide association study data reveal an association between the key nucleosome remodeling and deacetylase complex and bipolar disorder development., PMID:29280245
RNA-Seq reveals seven promising candidate genes affecting the proportion of thick egg albumen in layer-type chickens., PMID:29273734
The FOXP2-Driven Network in Developmental Disorders and Neurodegeneration., PMID:28798667
Study on expression of CDH4 in lung cancer., PMID:28095912
Long non-coding RNA linc-cdh4-2 inhibits the migration and invasion of HCC cells by targeting R-cadherin pathway., PMID:27765630
Genetic variations associated with gemcitabine treatment outcome in pancreatic cancer., PMID:27749787
CDH4 suppresses the progression of salivary adenoid cystic carcinoma via E-cadherin co-expression., PMID:27783992
Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex., PMID:27151949
Development of Bipotent Cardiac/Skeletal Myogenic Progenitors from MESP1+ Mesoderm., PMID:26771351
Time course and side-by-side analysis of mesodermal, pre-myogenic, myogenic and differentiated cell markers in the chicken model for skeletal muscle formation., PMID:26278933
Next-Generation Sequencing of Pulmonary Sarcomatoid Carcinoma Reveals High Frequency of Actionable MET Gene Mutations., PMID:26215952
UHRF1 promotes proliferation of gastric cancer via mediating tumor suppressor gene hypermethylation., PMID:26147747
Complex and dynamic expression of cadherins in the embryonic marmoset cerebral cortex., PMID:26081465
SDN-1/Syndecan Acts in Parallel to the Transmembrane Molecule MIG-13 to Promote Anterior Neuroblast Migration., PMID:26022293
Comparative detection of aberrantly methylated DNA in preoperative and postoperative stool from patients with colorectal cancers., PMID:24980446