Catalog No.
YHF04101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser2-Glu98
Predicted molecular weight
12.95 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P54652
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HSPA2, Heat shock-related 70 kDa protein 2, Heat shock 70 kDa protein 2
HSPA2 influences the differentiation and production of immunomodulatory mediators in human immortalized epidermal keratinocyte lines., PMID:40287440
The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision., PMID:40063400
Male germ cells with Bag5 deficiency show reduced spermiogenesis and exchange of basic nuclear proteins., PMID:39992433
LncRNA SERPINB9P1 Mitigates Cerebral Injury Induced by Oxygen‒Glucose Deprivation/Reoxygenation by Interacting with HSPA2., PMID:39798045
Proteomic analysis of the nonstructural protein 2-host protein interactome reveals a novel regulatory role of SH3 domain-containing kinase-binding protein 1 in porcine reproductive and respiratory syndrome virus replication and apoptosis., PMID:39755310
Molecular response of canine testis to GnRH agonist: Insights into AR, HIF-1α, and HSPs expression during arrest and recovery of spermatogenesis., PMID:39631561
Transcriptome analysis of jejunal mucosal tissue in breeder hens exposed to acute heat stress., PMID:39561558
Investigating the effects of COVID-19 on sperm in male smokers: A prospective integrated proteomic and metabolomic study., PMID:39406274
[Knockout of Hsp70 Genes Modulates Age-Related Transcriptomic Changes in Leg Muscles and Reduces the Locomotion Speed and Lifespan of Drosophila melanogaster]., PMID:39355882
EpidermaQuant: Unsupervised Detection and Quantification of Epidermal Differentiation Markers on H-DAB-Stained Images of Reconstructed Human Epidermis., PMID:39272688
The diabetic myocardial transcriptome reveals Erbb3 and Hspa2 as a novel biomarkers of incident heart failure., PMID:39180332
Genome-Wide Identification, Molecular Characterization, and Expression Analysis of the HSP70 and HSP90 Gene Families in Thamnaconus septentrionalis., PMID:38891896
Gene Expression and DNA Methylation Profiling Suggest Potential Biomarkers for Azacitidine Resistance in Myelodysplastic Syndrome., PMID:38731939
Proteomic biomarkers in seminal plasma as predictors of reproductive potential in azoospermic men., PMID:38654926
The human testis-enriched HSPA2 interacts with HIF-1α in epidermal keratinocytes, yet HIF-1α stability and HIF-1-dependent gene expression rely on the HSPA (HSP70) activity., PMID:38641179
Transcriptome Analysis of Key Genes Involved in the Initiation of Spermatogonial Stem Cell Differentiation., PMID:38397131
Characterised intron retention profiles in muscle tissue of idiopathic inflammatory myopathy subtypes., PMID:38302260
Vitrified turkey ovarian tissue cultured and assessed through gene expression patterns: A potential screening tool., PMID:38072182
Human umbilical cord mesenchymal stem cells (hUC-MSCs) alleviate paclitaxel-induced spermatogenesis defects and maintain male fertility., PMID:37574561
Transcriptome Analysis of the Inhibitory Effects of 20(S)-Protopanaxadiol on NCI-H1299 Non-Small Cell Lung Cancer Cells., PMID:37570716
Methylated tumor suppressor gene SCARA5 inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma., PMID:37554122
Comprehensive analysis of resistance mechanisms to EGFR-TKIs and establishment and validation of prognostic model., PMID:37532906
iTRAQ-based proteomic analysis provides novel insight into the postnatal testicular development of Hu sheep., PMID:37390892
Melatonin improves the ability of spermatozoa to bind with oocytes in the mouse., PMID:37068786
The role of spermatozoa-zona pellucida interaction in selecting fertilization-competent spermatozoa in humans., PMID:37020592
Heat shock protein A2 is a novel extracellular vesicle-associated protein., PMID:36959387
Multi-omics integration to identify the genetic expression and protein signature of dilated and ischemic cardiomyopathy., PMID:36860278
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice., PMID:36636478
CLPP Depletion Causes Diplotene Arrest; Underlying Testis Mitochondrial Dysfunction Occurs with Accumulation of Perrault Proteins ERAL1, PEO1, and HARS2., PMID:36611846
Genomic Profiling Reveals the Variant Landscape of Sporadic Parathyroid Adenomas in Chinese Population., PMID:36611251
HIV-1 gp120 Protein Activates Cyclin-Dependent Kinase 1, a Possible Link to Central Nervous System Cell Death., PMID:36560797
Research Note: Integrated transcriptomic and metabolomic analysis reveals potential candidate genes and regulatory pathways associated with egg weight in ducks., PMID:36481710
Acute exposure to high temperature affects expression of heat shock proteins in altricial avian embryos., PMID:36462856
DNA Methylation Architecture Provides Insight into the Pathogenesis of Upper Tract Urothelial Carcinoma: A Systematic Review and Meta-Analysis., PMID:36376170
HSPA1A, HSPA2, and HSPA8 Are Potential Molecular Biomarkers for Prognosis among HSP70 Family in Alzheimer's Disease., PMID:36246562
Transcriptomic signatures responding to PKM2 activator TEPP-46 in the hyperglycemic human renal proximal epithelial tubular cells., PMID:36120453
Hsa_circ_0000437 promotes pathogenesis of gastric cancer and lymph node metastasis., PMID:36109630
Varicocoele-associated male infertility: Cellular and molecular perspectives of pathophysiology., PMID:36040837
Protective effect of melatonin on alleviating early oxidative stress induced by DOX in mice spermatogenesis and sperm quality maintaining., PMID:35850689
Molecular Chaperone HSPA2 Distribution During Hyaluronic Acid Selection in Human Sperm., PMID:35819578
Targeted Analysis of HSP70 Isoforms in Human Spermatozoa in the Context of Capacitation and Motility., PMID:35742939
Targeting UPR signaling pathway by dasatinib as a promising therapeutic approach in chronic myeloid leukemia., PMID:35716222
FSIP2 plays a role in the acrosome development during spermiogenesis., PMID:35654582
Tumorigenic and immunological roles of Heat shock protein A2 in pancreatic cancer: a bioinformatics analysis., PMID:35649069
Lycopene improves testicular damage and sperm quality in experimentally induced varicocele: Relationship with apoptosis, hypoxia, and hyperthermia., PMID:35592276
[Effects of Yishen Tongluo Prescription on the PI3K-Akt-MTOR pathway and the protein and mRNA expressions of CatSper-1 and HSPA2 in the testis tissue of oligoasthenospermia rats]., PMID:37477484
Proteomic analysis identifies potential markers in small white and small yellow follicle development in chickens., PMID:35296374
Immunofluorescence and High-Resolution Microscopy Reveal New Insights in Human Globozoospermia., PMID:35163651
Role of Hub Genes in the Occurrence and Development of Testicular Cancer Based on Bioinformatics., PMID:35082515
Melatonin ameliorates paclitaxel-induced mice spermatogenesis and fertility defects., PMID:35001532
For research use only. Not for human or drug use.
