Catalog No.
YHE95701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro584-Ala721
Predicted molecular weight
17.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P52824
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DGKQ, Diglyceride kinase theta, DGK-theta, DAG kinase theta, DGKtheta, DAGK4, Diacylglycerol kinase theta
Insight of action mechanism of Astragaloside IV for relieving of cerebral ischemic injury in a rat model of middle cerebral artery occlusion reperfusion via proteomics and network pharmacology., PMID:40208491
A network-based systems genetics framework identifies pathobiology and drug repurposing in Parkinson's disease., PMID:39837893
A network-based systems genetics framework identifies pathobiology and drug repurposing in Parkinson's disease., PMID:39483867
Expanding causal genes for Parkinson's disease via multi-omics analysis., PMID:37865667
Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood., PMID:36759259
Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis., PMID:36525963
Brain Proteome-Wide and Transcriptome-Wide Asso-ciation Studies, Bayesian Colocalization, and Mendelian Randomization Analyses Reveal Causal Genes of Parkinson's Disease., PMID:36511626
Tumor Growth in the High Frequency Medulloblastoma Mouse Model Ptch1+/-/Tis21KO Has a Specific Activation Signature of the PI3K/AKT/mTOR Pathway and Is Counteracted by the PI3K Inhibitor MEN1611., PMID:34395258
Association study of MCCC1/LAMP3 and DGKQ variants with Parkinson's disease in patients of Malay ancestry., PMID:33559030
Genetic, Structural, and Functional Evidence Link TMEM175 to Synucleinopathies., PMID:31658403
Identifying Interaction Clusters for MiRNA and MRNA Pairs in TCGA Network., PMID:31514484
Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer., PMID:29965997
Congenital glaucoma and CYP1B1: an old story revisited., PMID:29556725
The 4p16.3 Parkinson Disease Risk Locus Is Associated with GAK Expression and Genes Involved with the Synaptic Vesicle Membrane., PMID:27508417
Impact of Parkinson's disease risk loci on age at onset., PMID:25914293
Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome., PMID:24097067
GAK rs1564282 and DGKQ rs11248060 increase the risk for Parkinson's disease in a Chinese population., PMID:23618683
Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2., PMID:22451204
Genome-wide association study confirms extant PD risk loci among the Dutch., PMID:21248740
Genomewide association study for susceptibility genes contributing to familial Parkinson disease., PMID:18985386
For research use only. Not for human or drug use.
