Catalog No.
YHE89301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr10-Leu240
Predicted molecular weight
27.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P51858
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hepatoma-derived growth factor, HMG-1L2, HMG1L2, High mobility group protein 1-like 2, HDGF
NAP1L1 degradation by FBXW7 reduces the deubiquitination of HDGF-p62 signaling to stimulate autophagy and induce primary cisplatin chemosensitivity in nasopharyngeal carcinoma., PMID:40414865
Exploring new drug treatment targets for immune related bone diseases using a multi omics joint analysis strategy., PMID:40148470
HRP2 regulating MICU1-mediated Ca2+ overload to dictate chemoresistance of multiple myeloma., PMID:40058268
HDGF Knockout Suppresses Colorectal Cancer Progression and Drug Resistance by Modulating the DNA Damage Response., PMID:40001585
Proteome-wide Mendelian randomization identifies causal plasma proteins in prostate cancer development., PMID:39994764
Evaluation of circulating plasma proteins in prostate cancer using mendelian randomization., PMID:39287922
FGFR‑related phenotypic and functional profile of CAFs in prognostication of breast cancer (Review)., PMID:39219285
The m6A reader IGF2BP2 promotes ESCC progression by stabilizing HDGF mRNA., PMID:39206979
Binding Behavior of Human Hepatoma-Derived Growth Factor on SMYD1., PMID:39091133
Anti-HDGF Antibody Targets EGFR Tyrosine Kinase Inhibitor-Tolerant Cells in NSCLC Patient-Derived Xenografts., PMID:39041204
Basis of gene-specific transcription regulation by the Integrator complex., PMID:38906142
Profiling Kinase Activities for Precision Oncology in Diffuse Gastric Cancer., PMID:38271566
Determination of the Possible Target Genes of Hepatoma-derived Growth Factor in Hepatoma Cells., PMID:37652516
Neuroprotective effects of hepatoma-derived growth factor in models of Huntington's disease., PMID:37580082
Genome-wide analysis of RNA-binding protein co-expression with alternative splicing events in acute respiratory distress syndrome following hematopoietic stem cell transplantation., PMID:37565892
Decreased acetylation of HDGF improves oviduct production in Rana dybowskii, Rana amurensis, and Rana huanrenensis., PMID:37384958
Identifying Key Genes and Functionally Enriched Pathways in Osteoporotic Patients by Weighted Gene Co-Expression Network Analysis., PMID:37358674
Potential common molecular mechanisms between Sjögren syndrome and inclusion body myositis: a bioinformatic analysis and in vivo validation., PMID:37153570
Proteomic Discovery and Array-Based Validation of Biomarkers from Urinary Exosome by Supramolecular Probe., PMID:37126797
Independent Signaling of Hepatoma Derived Growth Factor and Tumor Necrosis Factor-Alpha in Human Gastric Cancer Organoids Infected by Helicobacter pylori., PMID:37047540
Identification and Biological Evaluation of a Water-Soluble Fullerene Nanomaterial as BTK Kinase Inhibitor., PMID:37025922
Hepatocyte-Specific Triggering of Hepatic Stellate Cell Profibrotic Activation by Apoptotic Bodies: The Role of Hepatoma-Derived Growth Factor, HIV, and Ethanol., PMID:36982417
Clinicopathological features and immunophenotype of Silva pattern system in endocervical adenocarcinoma., PMID:36928883
BLM promotes malignancy in PCa by inducing KRAS expression and RhoA suppression via its interaction with HDGF and activation of MAPK/ERK pathway., PMID:36574142
[miR-29a-3p Targets Hepatoma-Derived Growth Factor to Inhibit the Proliferation and Promote the Apoptosis of E6-1 Cells]., PMID:36476884
RNA-m6A modification of HDGF mediated by Mettl3 aggravates the progression of atherosclerosis by regulating macrophages polarization via energy metabolism reprogramming., PMID:36265285
NSUN2-mediated mRNA m5C Modification Regulates the Progression of Hepatocellular Carcinoma., PMID:36183976
NAP1L1 promotes the growth of colon cancer by activating HDGF/DDX5., PMID:36148951
Application of miRNA Biomarkers in Predicting Overall Survival Outcomes for Lung Adenocarcinoma., PMID:36147635
Marsdenia tenacissima extract disturbs the interaction between tumor-associated macrophages and non-small cell lung cancer cells by targeting HDGF., PMID:35973634
Alterations in mRNA Expression Levels of Tight Junction Proteins in the Blood Cells of Smokers with or without COPD., PMID:35642119
Association of serum hepatoma-derived growth factor levels with disease activity in rheumatoid arthritis: A pilot study., PMID:35500218
Extracellular vesicle proteomic analysis leads to the discovery of HDGF as a new factor in multiple myeloma biology., PMID:35395072
lncRNA DLG1-AS1 promotes cervical cancer cell gemcitabine resistance by regulating miR-16-5p/HDGF., PMID:35388952
NAP1L1 promotes tumor proliferation through HDGF/C-JUN signaling in ovarian cancer., PMID:35351053
Hepatoma Derived Growth Factor Enhances Oligodendrocyte Genesis from Subventricular Zone Precursor Cells., PMID:35293825
An Unfolded Protein Response-Related mRNA Signature Predicting the Survival and Therapeutic Effect of Hepatocellular Carcinoma., PMID:35125080
Long noncoding RNA LINC00649 functions as a microRNA‑432‑5p sponge to facilitate tumourigenesis in colorectal cancer by upregulating HDGF., PMID:35088877
Specificity protein 1-induced serine peptidase inhibitor, Kunitz Type 1 antisense RNA1 regulates colorectal cancer cell proliferation, migration, invasion and apoptosis through targeting heparin binding growth factor via sponging microRNA-214., PMID:35068341
Kinase Sensing Based on Protein Interactions at the Catalytic Site., PMID:35038192
Insulin-like growth factor 2 mRNA-binding protein 2-stabilized long non-coding RNA Taurine up-regulated gene 1 (TUG1) promotes cisplatin-resistance of colorectal cancer via modulating autophagy., PMID:35014946
NAP1L1 promotes proliferation and chemoresistance in glioma by inducing CCND1/CDK4/CDK6 expression through its interaction with HDGF and activation of c-Jun., PMID:34959221
G3BP2 regulated by the lncRNA LINC01554 facilitates esophageal squamous cell carcinoma metastasis through stabilizing HDGF transcript., PMID:34782720
NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth., PMID:34774047
A novel function of HRP-3 in regulating cell cycle progression via the HDAC-E2F1-Cyclin E pathway in lung cancer., PMID:34714604
Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension., PMID:34687693
NAP1L1 targeting suppresses the proliferation of nasopharyngeal carcinoma., PMID:34563951
Matrix-Bound Growth Factors are Released upon Cartilage Compression by an Aggrecan-Dependent Sodium Flux that is Lost in Osteoarthritis., PMID:34423304
Heparin-binding growth factor (HDGF) drives radioresistance in breast cancer by activating the STAT3 signaling pathway., PMID:34376200
NAP1L1 Functions as a Tumor Promoter via Recruiting Hepatoma-Derived Growth Factor/c-Jun Signal in Hepatocellular Carcinoma., PMID:34368121
For research use only. Not for human or drug use.
