Catalog No.
YHE64301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met139-Glu439
Predicted molecular weight
34.25 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P49327
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fatty acid synthase, FAS, FASN, Type I fatty acid synthase
The Splice Variant of the NCOR2 Gene BQ323636.1 Modulates ACSL4 Expression to Enhance Fatty Acid Metabolism and Support of Tumor Growth in Breast Cancer., PMID:40507798
Multi-Omic Profiling Identifies Conserved Metabolic Pathways Critical for SARS-CoV-2 Variants Infection., PMID:40502071
The sphingosine-1-phosphate receptor 2 S1PR2 mediates chronic glucocorticoid exposure-induced hepatic steatosis and hypertriglyceridemia., PMID:40490140
The EGR1-mediated lncRNA TENM3-AS1 potentiates gastric cancer metastasis via reprogramming fatty acid metabolism., PMID:40481489
CircHIPK3's dual role in promoting angiogenesis and inhibiting apoptosis through FASN mRNA stabilization in gallbladder cancer., PMID:40466438
COP I vesicles facilitate classical swine fever virus proliferation by transporting fatty acid synthase from the Golgi apparatus to the endoplasmic reticulum., PMID:40459259
Intestinal L-cell mechanoreception regulates hepatic lipid metabolism through GLP-1., PMID:40446026
Suppression of Monkeypox Virus by Downregulation of Fatty Acid Synthase and Upregulation of Cholesterol-25 Hydroxylase., PMID:40444438
Microencapsulation of Syzygium zeylanicum (L.) DC.: A novel strategy for improving antidiabetic and anti-inflammatory activities., PMID:40436547
Strontium regulating lipid metabolism of bovine hepatocytes via SIRT1/SREBPs pathway., PMID:40403884
Classical swine fever virus utilizes stearoyl-CoA desaturase 1-mediated lipid metabolism to facilitate viral replication., PMID:40387378
DHA suppresses hormone-sensitive and castration-resistant prostate cancer growth by decreasing de novo lipogenesis., PMID:40383250
Longitudinal expression profiles of key markers during stages of adipogenic differentiation of 3T3-L1 cells using the PPARG agonist rosiglitazone., PMID:40378617
Widespread discordance between mRNA expression, protein abundance and de novo lipogenesis activity in hepatocytes during the fed-starvation transition., PMID:40376090
Transcriptomic analysis reveals sexual dimorphism in lipid metabolism within largemouth bass (Micropterus salmoides) fed the high-fat diet., PMID:40373386
Characterizing differences in the muscle transcriptome between cattle with alternative LCORL-NCAPG haplotypes., PMID:40369436
Myriocin Restores Metabolic Homeostasis in dAGE-Exposed Mice via AMPK-PGC1α-Mediated Mitochondrial Activation and Systemic Lipid/Glucose Regulation., PMID:40362857
The Effect of Reduced Dietary Protein on Adipose Tissue in Local Krškopolje Pigs., PMID:40362677
CD36 molecule and AMP-activated protein kinase signaling drive docosahexaenoic acid-induced lipid remodeling in goat mammary epithelial cells., PMID:40348225
Inhibitory effects of kukoamine B on adipogenesis and lipid accumulation in vitro and obesity in vivo., PMID:40347845
Green Tea Epigallocatechin-3-gallate Ameliorates Lipid Accumulation and Obesity-Associated Metabolic Syndrome via Regulating Autophagy and Lipolysis in Preadipocytes and Adipose Tissue., PMID:40347183
Differential Effects of Wild Blueberry (Poly)Phenol Metabolites in Modulating Lipid Metabolism and Oxidative Stress in 3T3-L1 Adipocytes., PMID:40345987
Perilipin1 mediates milk fat synthesis in bovine mammary epithelial cells through SREBP1 phosphorylation., PMID:40338730
Agouti-signaling protein (ASIP) improves bovine in vitro matured oocyte developmental competence and modulates lipid content., PMID:40338290
Metabolic effects of late-onset estradiol replacement in high-fat-fed ovariectomized mice., PMID:40331103
The impact of fatty acid synthase on HSV-1 infection dynamics., PMID:40327680
The natural dihydrochalcone phloretin reduces lipid accumulation via downregulation of IIS and sbp-1/SREBP pathways in HepG2 cells and Caenorhabditis elegans., PMID:40326995
Cardamonin suppresses mTORC1/SREBP1 through reducing Raptor and inhibits de novo lipogenesis in ovarian cancer., PMID:40315213
Vaccarin treats lactation insufficiency through the ALKBH5-SFRP2-Wnt/β-catenin signaling pathway., PMID:40311715
NAMPT Impairs Vascular Permeability in Periodontitis by Influencing FASN-mediated Lipogenesis., PMID:40303304
PPARG Activation of Fatty Acid Metabolism Drives Resistance to Anti-HER2 Therapies in HER2-Positive Breast Cancer., PMID:40303293
p-Synephrine ameliorates non-alcoholic fatty liver disease by regulating liver-adipose axis via AMPK/NF-kappa B pathway., PMID:40294666
Identification of Key Genes Related to Intramuscular Fat Content of Psoas Major Muscle in Saba Pigs by Integrating Bioinformatics and Machine Learning Based on Transcriptome Data., PMID:40282015
Caloric restriction alters NCOA2 splicing to regulate lipid metabolism in subcutaneous white adipose tissue., PMID:40267838
Genome-wide association studies of the fatty acid composition of Korean native chicken breast meat., PMID:40264524
Targeting oncogenic activation of FLT3/SREBP/FASN promotes the therapeutic effect of quizartinib involving disruption of mitochondrial phospholipids., PMID:40263296
Mechanism of polyphenol-pea starch complexes on reducing fat accumulation in Caenorhabditis elegans., PMID:40253205
Glioblastoma cells secrete ICAM1 via FASN signaling to promote glioma-associated macrophage infiltration., PMID:40252818
HKDC1 promotes ovarian cancer progression through boosting lipid metabolism and immune escape by stabilizing G6PC/G6PC2., PMID:40234623
Sesamin regulates breast cancer through reprogramming of lipid metabolism., PMID:40233124
Exposure to submicroplastics promotes the progression of nonalcoholic fatty liver disease in ApoE-deficient mice., PMID:40222581
Targeting B7-H3 inhibition-induced activation of fatty acid synthesis boosts anti-B7-H3 immunotherapy in triple-negative breast cancer., PMID:40221152
Core Molecular Clock Factors Regulate Osteosarcoma Stem Cell Survival and Behavior via CSC/EMT Pathways and Lipid Droplet Biogenesis., PMID:40214471
Tspo Depletion Exacerbates Steatosis Through Fatty Acid Uptake., PMID:40195072
Tumor acidosis supports cancer cell lipid uptake via a rapid transporter-independent mechanism., PMID:40190115
Membrane-associated ring-CH-type finger 2 protects against metabolic dysfunction-associated fatty liver disease by targeting fatty acid synthase., PMID:40189099
Baicalin alleviates lipid accumulation in adipocytes via inducing metabolic reprogramming and targeting Adenosine A1 receptor., PMID:40188992
Prediction of potential targets of aloe-emodin in the treatment of hepatocellular carcinoma using network pharmacology combined with bioinformatics., PMID:40186059
A complex multisystem disorder including hypopituitarism and hypoparathyroidism, associated with mutation in the gene encoding fatty acid synthase (FASN)., PMID:40185395
Fatty acid synthase global inducible knockout does not alter brain fatty acid concentrations but attenuates cholesterol synthesis in the adult mouse., PMID:40185011
For research use only. Not for human or drug use.
