Catalog No.
YHE38801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser115-Gly209
Predicted molecular weight
12.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43005
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EAAC1, EAAT3, Sodium-dependent glutamate/aspartate transporter 3, Solute carrier family 1 member 1, Excitatory amino-acid carrier 1, SLC1A1, Excitatory amino acid transporter 3, Neuronal and epithelial glutamate transporter
Ferroptosis Contributes to Retinal Ganglion Cell Loss in GLAST Knockout Mouse Model of Normal Tension Glaucoma., PMID:40402516
Alteration in Ca2+ signaling-related genes in schizophrenia., PMID:40388041
The development of a high-throughput acoustic droplet ejection mass-spectrometry assay and a solid-supported membrane (SSM)-based electrophysiological assay to study the pharmacological inhibition of SLC1-A3, -A2 and -A1 in a drug discovery program., PMID:40308755
Oral exposure to nanoplastics and food allergy in mice fed a normal or high-fat diet., PMID:40252413
Effects of microencapsulated essential oils and seaweed meal on growth performance, digestive enzymes, intestinal morphology, liver functions, and plasma biomarkers in broiler chickens., PMID:40151066
SIRT4 Protects Retina Against Excitotoxic Injury by Promoting OPA1-Mediated Müller Glial Cell Mitochondrial Fusion and GLAST Expression., PMID:39873651
Dietary 5-hydroxytryptophan supplementation improves growth performance and intestinal health of weaned piglets., PMID:39707487
Investigation and validation of neurotransmitter receptor-related biomarkers for forecasting clinical outcomes and immunotherapeutic efficacy in breast cancer., PMID:39615806
N-Acetylcysteine Alleviates Depressive-Like Behaviors in Adolescent EAAC1-/- Mice and Early Life Stress Model Rats., PMID:39494328
Sex-dependent effects of short-term ethanol, energy drinks and acute noise exposure on hippocampal oxidative balance and glutamate transporter EAAT-1 during rat adolescence., PMID:39366467
Molecular Dynamic Simulations Reveal that Water-Soluble QTY-Variants of Glutamate Transporters EAA1, EAA2 and EAA3 Retain the Conformational Characteristics of Native Transporters., PMID:39322794
Pentylenetetrazole-Induced Seizures Cause Short-Term Changes in the Phenotype of Microglial and Astroglial Cells in the Hippocampus and Temporal Cortex of Young Male Wistar Rats., PMID:39305083
Increased forebrain EAAT3 expression confers resilience to chronic stress., PMID:39245629
An Ultrasensitive Biosensor for Probing Subcellular Distribution and Mitochondrial Transport of l-2-Hydroxyglutarate., PMID:39005231
Cytoplasmic Lipid Droplets Predict Worse Prognosis in Diffuse Large B-Cell Lymphoma: Next-Generation Sequencing Deciphering Lipogenic Genes., PMID:38979928
A spatiotemporal map of co-receptor signaling networks underlying B cell activation., PMID:38850533
Oxidative stress plays an important role in the central regulatory mechanism of orofacial hyperalgesia under low estrogen conditions., PMID:38759799
High Dietary Folic Acid Supplementation Reduced the Composition of Fatty Acids and Amino Acids in Fortified Eggs., PMID:38611353
Association of rs11081062 polymorphism of DLGAP1 gene and levels of SLC1A1 protein with obsessive-compulsive disorder., PMID:38593060
Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos., PMID:38529784
Impaired neuronal macroautophagy in the prelimbic cortex contributes to comorbid anxiety-like behaviors in rats with chronic neuropathic pain., PMID:38522078
Forebrain EAAT3 Overexpression Increases Susceptibility to Amphetamine-Induced Repetitive Behaviors., PMID:38514191
MIR96 Has Good Potential to Differentiate Human Bone Marrow-Derived Mesenchymal Stem Cells into Photoreceptor-Like Cells., PMID:38511985
Anesthetic Sevoflurane Induces Enlargement of Dendritic Spine Heads in Mouse Neurons via Tau-Dependent Mechanisms., PMID:38507523
Prognosis prediction and risk stratification of breast cancer patients based on a mitochondria-related gene signature., PMID:38310106
Expression assay of calcium signaling related lncRNAs in autism., PMID:38265729
Metabolomics analysis to interpret changes in physiological and metabolic responses to chronic heat stress in Pekin ducks., PMID:38110095
EAAT3 impedes oligodendrocyte remyelination in chronic cerebral hypoperfusion-induced white matter injury., PMID:37803915
A pilot study on glutamate receptor and carrier gene variants and risk of childhood autism spectrum., PMID:37578654
HIF-1α drives resistance to ferroptosis in solid tumors by promoting lactate production and activating SLC1A1., PMID:37542723
Abundance of Amino Acid Transporters and mTOR Pathway Components in the Gastrointestinal Tract of Lactating Holstein Cows., PMID:37048445
A Spatiotemporal Map of Co-Receptor Signaling Networks Underlying B Cell Activation., PMID:36993395
An evaluation of the thermoregulatory potential of in ovo delivered bioactive substances (probiotic, folic acid, and essential oil) in broiler chickens., PMID:36924590
Nox4-and Tf/TfR-mediated peroxidation and iron overload exacerbate neuronal ferroptosis after intracerebral hemorrhage: Involvement of EAAT3 dysfunction., PMID:36805044
Revealing genetic links of Type 2 diabetes that lead to the development of Alzheimer's disease., PMID:36711310
Dietary tea tree (Melaleuca alternifolia) oil supplementation enhances the expressions of amino acid transporters in goat ileal mucosa and improves intestinal immunity., PMID:36348789
Epstein-Barr virus infection controls the concentration of the intracellular antioxidant glutathione by upregulation of the glutamate transporter EAAT3 in tumor cells., PMID:36344769
Intact amphetamine-induced behavioral sensitization in mice with increased or decreased neuronal glutamate transporter SLC1A1/EAAT3., PMID:36096294
Dietary Moringa oleifera leaf powder improves jejunal permeability and digestive function by modulating the microbiota composition and mucosal immunity in heat stressed rabbits., PMID:35725877
SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors., PMID:35459936
Dysfunction of EAAT3 Aggravates LPS-Induced Post-Operative Cognitive Dysfunction., PMID:35323793
Amino Acid Solute Carrier Transporters in Inflammation and Autoimmunity., PMID:35152203
The Amino Acids Sensing and Utilization in Response to Dietary Aromatic Amino Acid Supplementation in LPS-Induced Inflammation Piglet Model., PMID:35111801
Developmental impact of glutamate transporter overexpression on dopaminergic neuron activity and stereotypic behavior., PMID:35058566
Enmein Decreases Synaptic Glutamate Release and Protects against Kainic Acid-Induced Brain Injury in Rats., PMID:34884781
Regulation of NRG-1-ErbB4 signaling and neuroprotection by exogenous neuregulin-1 in a mouse model of epilepsy., PMID:34742879
SLC1A1 mediated glutamine addiction and contributed to natural killer T-cell lymphoma progression with immunotherapeutic potential., PMID:34628354
Evidence for the interaction of COX-2 with mGluR5 in the regulation of EAAT1 and EAAT3 protein levels in the mouse hippocampus. The influence of oxidative stress mechanisms., PMID:34529964
Serum biochemical parameters and amino acids metabolism are altered in piglets by early-weaning and proline and putrescine supplementations., PMID:34258421
Altered Grooming Syntax and Amphetamine-Induced Dopamine Release in EAAT3 Overexpressing Mice., PMID:34234648
For research use only. Not for human or drug use.
