Catalog No.
YHE39401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn217-Gln359
Predicted molecular weight
18.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43115
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PTGER3, PGE2-R, PGE2 receptor EP3 subtype, Prostanoid EP3 receptor, Prostaglandin E2 receptor EP3 subtype, PGE receptor EP3 subtype
Discovery and Functional Validation of EP3 Receptor Ligands with Therapeutic Potential in Cardiovascular Disease., PMID:40430020
Characterization of ROMK cellular heterogeneity along the mouse kidney thick ascending limb., PMID:40358700
Acetylsalicylic acid aggravates anaphylaxis in a PGE2-dependent manner., PMID:40026245
Combining machine learning with external validation to explore necroptosis and immune response in moyamoya disease., PMID:39948449
Study on the Chemical Composition and Anti-Tumor Mechanisms of Clausena lansium Fruit By-Products: Based on LC-MS, Network Pharmacology Analysis, and Protein Target Validation., PMID:39682950
The EP3-ZNF488 Axis Promotes Self-Renewal of Glioma Stem-Like Cells to Induce Resistance to Tumor Treating Fields., PMID:39412953
Sustainable synthesis of bakuchiol-mediated gold nanoparticles for drug delivery against bacterial strains and tumor microenvironments, and its in silico target proteins identification., PMID:39385982
Prostaglandin E2 regulates the plasminogen activator pathway in human endometrial endothelial cells: a new in vitro model to investigate heavy menstrual bleeding., PMID:39038609
Inducible deletion of the prostaglandin EP3 receptor in kidney tubules of male and female mice has no major effect on water homeostasis., PMID:38961846
Associations of E-proteinoid 3 receptor genetic polymorphisms with salt sensitivity, longitudinal blood pressure changes, and hypertension incidence in Chinese adults., PMID:38952049
PTGER3 knockdown inhibits the vulnerability of triple-negative breast cancer to ferroptosis., PMID:38566528
Parallel neural pathways control sodium consumption and taste valence., PMID:37989313
Chromatin remodeling of prostaglandin signaling in smooth muscle enables mouse embryo passage through the female reproductive tract., PMID:37714160
Correlation of Reduced PTGER3 Expression with Prognosis and Immune Infiltration in Clear Cell Renal Carcinoma., PMID:37455526
Posttranscriptional regulation of the prostaglandin E receptor spliced-isoform EP3-γ and its implication in pancreatic β-cell failure., PMID:37171267
Diurnal regulation of metabolism by Gs-alpha in hypothalamic QPLOT neurons., PMID:37141220
An airway-to-brain sensory pathway mediates influenza-induced sickness., PMID:36890237
Examining SNP-SNP interactions and risk of clinical outcomes in colorectal cancer using multifactor dimensionality reduction based methods., PMID:35991579
Study on the Mechanism of Astragalus Polysaccharide in Treating Pulmonary Fibrosis Based on "Drug-Target-Pathway" Network., PMID:35370663
Implications of Human Antimicrobial Peptide Defensin Beta-1 in Clinical Oral Squamous Cell Carcinoma Patients via an Integrated Bioinformatics Approach., PMID:35222682
Synergistic Cytokine Production by ATP and PGE2 via P2X4 and EP3 Receptors in Mouse Bone-Marrow-Derived Mast Cells., PMID:35203267
Prostaglandin E2 receptor 3 promotes M1 macrophages polarization in unexplained recurrent pregnancy loss., PMID:35134851
Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes., PMID:35022648
Effects of DISC1 on Alzheimer's disease cell models assessed by iTRAQ proteomics analysis., PMID:34981809
Tumor Immune Microenvironment Related Gene-Based Model to Predict Prognosis and Response to Compounds in Ovarian Cancer., PMID:34966691
Effect of Piper cubeba total extract and isolated lignans on head and neck cancer cell lines and normal fibroblasts., PMID:34924135
Identification of Impacted Pathways and Transcriptomic Markers as Potential Mediators of Pulmonary Fibrosis in Transgenic Mice Expressing Human IGFBP5., PMID:34830489
Sexual dimorphism in prostacyclin-mimetic responses within rat mesenteric arteries: A novel role for KV 7.1 in shaping IP receptor-mediated relaxation., PMID:34766649
Sputum microRNA-screening reveals Prostaglandin EP3 receptor as selective target in allergen-specific immunotherapy., PMID:34514658
Explore the potential molecular mechanism of polycystic ovarian syndrome by protein-protein interaction network analysis., PMID:34507653
Comparative transcriptome analysis reveals potential testosterone function-related regulatory genes/pathways of Leydig cells in immature and mature buffalo (Bubalus bubalis) testes., PMID:34363886
Prostaglandin EP3 receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistance., PMID:34229444
The underlying molecular mechanism and drugs for treatment in adrenal cortical carcinoma., PMID:34220331
Prostaglandin E1 attenuates AngII-induced cardiac hypertrophy via EP3 receptor activation and Netrin-1upregulation., PMID:34147480
Hsa_circ_0000301 facilitates the progression of cervical cancer by targeting miR-1228-3p/IRF4 Axis., PMID:34020619
Identification of Molecular Subtypes and Key Genes of Atherosclerosis Through Gene Expression Profiles., PMID:33996893
The impact of removing former drinkers from genome-wide association studies of AUDIT-C., PMID:33861876
Breast adipose tissue macrophages (BATMs) have a stronger correlation with breast cancer survival than breast tumor stroma macrophages (BTSMs)., PMID:33849622
Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS-1 (832/3) cell glucose-stimulated insulin secretion., PMID:33694300
PTGER3 and MMP-2 play potential roles in diabetic nephropathy via competing endogenous RNA mechanisms., PMID:33435900
Prediction of hub genes of Alzheimer's disease using a protein interaction network and functional enrichment analysis., PMID:33412755
Larger endothelium-dependent contractions in iliac arteries of adult SHRs are attributed to differential downregulation of TP and EP3 receptors in the vessels of WKYs and SHRs during the transition from adolescence to adulthood., PMID:33347824
Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats., PMID:33165770
Differential properties of E prostanoid receptor-3 and thromboxane prostanoid receptor in activation by prostacyclin to evoke vasoconstrictor response in the mouse renal vasculature., PMID:33047360
The crosstalk between bone metabolism, lncRNAs, microRNAs and mRNAs in coronary artery calcification., PMID:32971215
The molecular, functional and phylogenetic characterization of PGE2 receptors reveals their different roles in the immune response of the teleost fish gilthead seabream (Sparus aurata L.)., PMID:32738336
EP3 Is an Independent Prognostic Marker Only for Unifocal Breast Cancer Cases., PMID:32580276
Prostaglandin E2 receptor 3 (EP3) signaling promotes migration of cervical cancer via urokinase-type plasminogen activator receptor (uPAR)., PMID:32488496
mPGES-1/PGE2 promotes the growth of T-ALL cells in vitro and in vivo by regulating the expression of MTDH via the EP3/cAMP/PKA/CREB pathway., PMID:32251289
Identification of the key genes and pathways involved in the tumorigenesis and prognosis of kidney renal clear cell carcinoma., PMID:32144299
For research use only. Not for human or drug use.
