Catalog No.
YHE16701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asn433
Predicted molecular weight
50.94 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35998
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MSS1, Protein MSS1, Proteasome 26S subunit ATPase 2, 26S proteasome AAA-ATPase subunit RPT1, PSMC2, 26S proteasome regulatory subunit 7
PSMC2 upregulation enhances epithelial-to-mesenchymal transition in glioblastoma via activating AKT/GSK3β/β-catenin axis., PMID:40233917
Unlocking the genetic code: a comprehensive Genome-Wide association study and gene set enrichment analysis of cell-mediated immunity in chickens., PMID:40181279
Rational strategies for designing next-generation oncolytic viruses based on transcriptome analysis of tumor cells infected with oncolytic herpes simplex virus-1., PMID:39850819
Proteomic Analysis of Biomarkers Predicting Treatment Response in Patients with Head and Neck Cancers., PMID:39684225
Hsa_circ_0007718 facilitates the progression of colorectal cancer by regulating the miR-1299/PSMC2 axis., PMID:39396594
Tianhe Zhuifeng Gao reverses inflammatory response and attenuates bone/cartilage destruction in rheumatoid arthritis via PSMC2-RUNX2-COL1A1 axis based on transcriptional regulatory network analysis and experimental validation., PMID:38971108
A Multistep In Silico Approach Identifies Potential Glioblastoma Drug Candidates via Inclusive Molecular Targeting of Glioblastoma Stem Cells., PMID:38619743
PSMC2 promotes glioma progression by regulating immune microenvironment and PI3K/AKT/mTOR pathway., PMID:38569452
The Absence of Intra-Tumoral Tertiary Lymphoid Structures is Associated with a Worse Prognosis and mTOR Signaling Activation in Hepatocellular Carcinoma with Liver Transplantation: A Multicenter Retrospective Study., PMID:38498682
Investigation of the Proteasome 26S Subunit, ATPase Family Genes as Potential Prognostic Biomarkers and Therapeutic Targets for Hepatocellular Carcinoma., PMID:38370535
[Identification and validation of novel biomarkers for cold-dampness syndrome of rheumatoid arthritis based on integration of multiple bioinformatics methods]., PMID:38212032
PSMC2 knockdown exerts an anti-tumor role in nasopharyngeal carcinoma through regulating AKT signaling pathway., PMID:38123344
Hydroquinidine displays a significant anticarcinogenic activity in breast and ovarian cancer cells via inhibiting cell-cycle and stimulating apoptosis., PMID:37529110
The prognostic value of 19S ATPase proteasome subunits in acute myeloid leukemia and other forms of cancer., PMID:37502358
Analyzing and Comparing Omicron Lineage Variants Protein-Protein Interaction Network Using Centrality Measure., PMID:37016628
Genetic Alterations in Members of the Proteasome 26S Subunit, AAA-ATPase (PSMC) Gene Family in the Light of Proteasome Inhibitor Resistance in Multiple Myeloma., PMID:36672481
Salmonella Typhimurium induces genome-wide expression and phosphorylation changes that modulate immune response, intracellular survival and vesicle transport in infected neutrophils., PMID:36450302
Italian Precision Medicine in Pediatric Oncology: Moving beyond Actionable Alterations., PMID:36232538
PSMC2 is overexpressed in glioma and promotes proliferation and anti-apoptosis of glioma cells., PMID:35287689
Identifying Potential Mitochondrial Proteome Signatures Associated with the Pathogenesis of Pulmonary Arterial Hypertension in the Rat Model., PMID:35237384
PSMC2 knockdown inhibits the progression of oral squamous cell carcinoma by promoting apoptosis via PI3K/Akt pathway., PMID:34979867
PSMC2 knockdown suppressed tumor progression of skin cutaneous melanoma., PMID:34716318
Knockdown of PSMC2 contributes to suppression of cholangiocarcinoma development by regulating CDK1., PMID:34499615
Prognoses and genomic analyses of proteasome 26S subunit, ATPase (PSMC) family genes in clinical breast cancer., PMID:34329194
PSMC2/CCND1 axis promotes development of ovarian cancer through regulating cell growth, apoptosis and migration., PMID:34294689
Overexpression of PSMC2 promotes the tumorigenesis and development of human breast cancer via regulating plasminogen activator urokinase (PLAU)., PMID:34244472
The Silence of PSMC6 Inhibits Cell Growth and Metastasis in Lung Adenocarcinoma., PMID:34239933
Protein Aggregation Patterns Inform about Breast Cancer Response to Antiestrogens and Reveal the RNA Ligase RTCB as Mediator of Acquired Tamoxifen Resistance., PMID:34206811
PSMC2, ORC5 and KRTDAP are specific biomarkers for HPV-negative head and neck squamous cell carcinoma., PMID:33732365
Silencing Proteasome 26S Subunit ATPase 2 (PSMC2) Protects the Osteogenic Differentiation In Vitro and Osteogenesis In Vivo., PMID:33625534
Identification of key genes and functions of circulating tumor cells in multiple cancers through bioinformatic analysis., PMID:32972417
Proteasome malfunction activates the PPP3/calcineurin-TFEB-SQSTM1/p62 pathway to induce macroautophagy in the heart., PMID:32960686
NFE2L1 and NFE2L3 Complementarily Maintain Basal Proteasome Activity in Cancer Cells through CPEB3-Mediated Translational Repression., PMID:32366381
Silencing of Proteasome 26S Subunit ATPase 2 Regulates Colorectal Cancer Cell Proliferation, Apoptosis, and Migration., PMID:31715603
Lower miR-630 expression predicts poor prognosis of osteosarcoma and promotes cell proliferation, migration and invasion by targeting PSMC2., PMID:30915734
Global Ubiquitome Profiling Revealed the Roles of Ubiquitinated Proteins in Metabolic Pathways of Tea Leaves in Responding to Drought Stress., PMID:30862833
Differentially expressed proteins identified by TMT proteomics analysis in bone marrow microenvironment of osteoporotic patients., PMID:30739146
Understanding the regulatory mechanisms of milk production using integrative transcriptomic and proteomic analyses: improving inefficient utilization of crop by-products as forage in dairy industry., PMID:29843597
Series test of cluster and network analysis for lupus nephritis, before and after IFN-K-immunosuppressive therapy., PMID:28869321
Label-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line., PMID:28242843
A Genomic and Protein-Protein Interaction Analyses of Nonsyndromic Hearing Impairment in Cameroon Using Targeted Genomic Enrichment and Massively Parallel Sequencing., PMID:28075205
PSMC2 is up-regulated in osteosarcoma and regulates osteosarcoma cell proliferation, apoptosis and migration., PMID:27888613
Quantitative proteomic analysis of age-related subventricular zone proteins associated with neurodegenerative disease., PMID:27857231
Impact of Heat Stress on Cellular and Transcriptional Adaptation of Mammary Epithelial Cells in Riverine Buffalo (Bubalus Bubalis)., PMID:27682256
Identification of collaborative activities with oxidative phosphorylation in bipolar disorder., PMID:26124562
Transcriptional responses to temperature and low oxygen stress in Atlantic salmon studied with next-generation sequencing technology., PMID:24261939
A comparative genomic approach for identifying synthetic lethal interactions in human cancer., PMID:23980094
Role of S5b/PSMD5 in proteasome inhibition caused by TNF-α/NFκB in higher eukaryotes., PMID:22921402
Cancer vulnerabilities unveiled by genomic loss., PMID:22901813
TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions., PMID:22078707
For research use only. Not for human or drug use.
