Catalog No.
YHE13201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu1740-Glu1960
Predicted molecular weight
27.63 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35579
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NMMHC-IIA, Non-muscle myosin heavy chain IIa, Cellular myosin heavy chain, type A, Myosin heavy chain 9, NMMHC II-a, Non-muscle myosin heavy chain A, Myosin-9, MYH9, NMMHC-A, Myosin heavy chain, non-muscle IIa
Familial Idiopathic Glomerular Disease due to a Unique Renal-Predominant Phenotype of MYH9-Related Disease: A Case Report., PMID:40503181
Dragon's Blood Modulates Disulfidptosis-Related Genes to Alleviate Ischemic Brain Injury in Mice., PMID:40478465
Molecular Control of Non-Muscle Myosin II-A Aggregation and Intracellular Dynamics by motor- or tail-specific MYH9 Mutations., PMID:40475454
Lipid Droplet-Organized MDM2-Mediated P53 Degradation: A Metabolic Switch Governing Diet-Driven Tumor Progression., PMID:40470795
A novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway., PMID:40456011
A Comprehensive Multiomics Signature of Doxorubicin-Induced Cellular Senescence in the Postmenopausal Human Ovary., PMID:40452152
Systems Genetics Reveals the Gene Regulatory Mechanisms of Arrb2 in the Development of Autism Spectrum Disorders., PMID:40428426
The Long Noncoding RNA LINC02820 Promotes Tumor Growth and Metastasis Through Regulating MYH9 Expression in Esophageal Squamous Cell Carcinoma., PMID:40416600
Differential Genes Analysis and Validation of Disulfideptosis in Rat Myocardial Ischemia-Reperfusion Injury Model., PMID:40323799
Integrated bioinformatic analysis of immune infiltration and disulfidptosis related gene subgroups in type A aortic dissection., PMID:40258895
Female-biased vascular smooth muscle cell gene regulatory networks predict MYH9 as a key regulator of fibrous plaque phenotype., PMID:40236025
Pathologic and genomic characteristics of myoepithelioma-like tumor of the vulvar region: three case reports., PMID:40188333
YOD1 regulates microglial homeostasis by deubiquitinating MYH9 to promote the pathogenesis of Alzheimer's disease., PMID:40041897
Gut microbiota may affect Alzheimer's disease through synaptic function mediated by CAMs pathway: A study combining Mendelian randomization and bioinformatics., PMID:40034528
Analysis of ferroptosis-related key genes and regulatory networks in diabetic foot ulcers., PMID:40024299
Monoclonal Antibodies Targeting Porcine Macrophages Are Able to Inhibit the Cell Entry of Macrophage-Tropic Viruses (PRRSV and ASFV)., PMID:40006922
Chromobox protein homolog 7 suppresses the stem-like phenotype of glioblastoma cells by regulating the myosin heavy chain 9-NF-κB signaling pathway., PMID:39988672
Clinical, Morphologic, and Genomic Findings in Spitz Tumors With RET Fusion: A Series of 31 Cases., PMID:39986469
[Refractory immune thrombocytopenia revealing MYH9 related disease in a 64-year-old man]., PMID:39939231
SMYD4 promotes MYH9 ubiquitination through lysine monomethylation modification to inhibit breast cancer progression., PMID:39930544
MYH9 promotes malignant progression of glioma cells through regulating β-catenin stability via epithelial-mesenchymal transition signaling pathway., PMID:39920245
Rare dual MYH9-ROS1 fusion variants in a patient with lung adenocarcinoma: A case report., PMID:39854762
STING1 targets MYH9 to drive adipogenesis through the AKT/GSK3β/β-catenin pathway., PMID:39847995
Hearing loss occurs prior to thrombocytopenia in both mice and humans with DFNA1., PMID:39831886
Genetic variations and clinical significance in young-onset nasopharyngeal cancer: Analysis of EBV interaction with cellular receptor variants and viral glycoproteins., PMID:39790874
D-ribose-5-phosphate inactivates YAP and functions as a metabolic checkpoint., PMID:39755622
Interpretable machine learning-driven biomarker identification and validation for Alzheimer's disease., PMID:39730451
Dipeptidyl Peptidase 4 (DPP4) Exacerbates Osteoarthritis Progression in an Enzyme-Independent Manner., PMID:39680708
Clinical and genetic characteristics of 40 patients with nonmuscle myosin heavy chain 9-related disease (MYH9-RD) misdiagnosed as immune thrombocytopenia: a retrospective analysis in China., PMID:39672236
Amoeboid cells undergo durotaxis with soft end polarized NMIIA., PMID:39671466
Diagnostic and prognostic value of disulfidptosis-related genes in sepsis., PMID:39610785
Investigating gene expression datasets of hippocampus tissue to discover Alzheimer's disease-associated molecular markers., PMID:39604273
Endothelial FOSL1 drives angiotensin II-induced myocardial injury via AT1R-upregulated MYH9., PMID:39592734
Clinicopathological characteristics and favourable prognosis of paediatric cutaneous nodular fasciitis: a case series., PMID:39573982
FATS inhibits the Wnt pathway and induces apoptosis through degradation of MYH9 and enhances sensitivity to paclitaxel in breast cancer., PMID:39550407
Palmatine attenuates MYH9 mediated nuclear localization of AURKA to induce G2/M phase arrest in colorectal cancer cells., PMID:39536490
Rosiglitazone-induced white adipocyte browning is regulated by actin and Myh9., PMID:39510170
Borg5 restricts contractility and motility in epithelial MDCK cells., PMID:39503295
myh9b is a critical non-muscle myosin II encoding gene that interacts with myh9a and myh10 during zebrafish development in both compensatory and redundant pathways., PMID:39503257
Thick Ascending Limb Specific Inactivation of Myh9 and Myh10 Myosin Motors Results in Progressive Kidney Disease and Drives Sex-specific Cellular Adaptation in the Distal Nephron and Collecting Duct., PMID:39500539
Targeting the SPC25/RIOK1/MYH9 Axis to Overcome Tumor Stemness and Platinum Resistance in Epithelial Ovarian Cancer., PMID:39488790
CircSP3 encodes SP3-461aa to promote ccRCC progression via stabilizing MYH9 and activating the PI3K-Akt signaling pathway., PMID:39440063
Oncogenic GALNT5 confers FOLFIRINOX resistance via activating the MYH9/ NOTCH/ DDR axis in pancreatic ductal adenocarcinoma., PMID:39433745
LncRNA lncLLM Facilitates Lipid Deposition by Promoting the Ubiquitination of MYH9 in Chicken LMH Cells., PMID:39408647
MYH9::LTK Fusion in a Pediatric Acral Soft Tissue Spindle Cell Neoplasm., PMID:39394894
Proteomic insights into early-stage Alzheimer's disease: Identifying key neuronal proteins impacted by amyloid beta oligomers in an in vitro model., PMID:39362622
Study on the expression and prognostic relationship of MYL6B in liver cancer based on bioinformatics., PMID:39351463
Proteome of plasma extracellular vesicles as a source of colorectal cancer biomarkers., PMID:39324200
The p-MYH9/USP22/HIF-1α axis promotes lenvatinib resistance and cancer stemness in hepatocellular carcinoma., PMID:39300073