Catalog No.
YHE07601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu781
Predicted molecular weight
87.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35222
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CTNNB, Catenin beta-1, CTNNB1, Beta-catenin
Basal cell adenoma with S100 protein-positive "stroma": a distinct triphasic salivary gland neoplasm characterized by CTNNB1 mutation., PMID:40515848
PD-L1 Expression is Mediated by microRNA Processing, Wnt/β-Catenin Signaling, and Chemotherapy in Wilms Tumor., PMID:40512079
Mechanisms of tumor heterogeneity in TACE-resistant liver cancer: Insights from single-cell and whole-exome sequencing., PMID:40489756
Identification of key proteins and pathways in myocardial infarction using machine learning approaches., PMID:40467768
Novel Aptamers Targeting Sclerostin Loop3 Improve Skeletal and Muscle Properties Without Adverse Cardiovascular Effects in Orchiectomized Mice., PMID:40464222
Probiotics ameliorate H. pylori-associated gastric β-catenin and COX-2 carcinogenesis signaling by regulating miR-185., PMID:40462044
Fermented black soldier fly larvae as a sustainable replacement for marine fish in Asian swamp eel diets., PMID:40453945
Wnt/β-catenin regulates Gli1 + osteogenic progenitors in condylar subchondral bone development and osteoarthritis., PMID:40448062
Precision targeting of β-catenin induces tumor reprogramming and immunity in hepatocellular cancers., PMID:40442146
AI-assisted multi-OMICS analysis reveals new markers for the prediction of AD., PMID:40441366
6-Gingerol overcomes TMZ resistance in GBM by suppressing EMT and cell migration via the PI3K/Akt/β-catenin/c-Myc pathway., PMID:40440961
The relationship between acid-sensing ion channel, ASIC2, and oncogenic β-catenin signaling in ovarian cancer., PMID:40437028
Interfering with AQP1 alleviates ferroptosis, improves mitochondrial function and energy metabolic disorder in hypoxia/reoxygenation-induced H9c2 cardiomyocytes via Wnt/β-catenin pathway., PMID:40436134
Polyphyllin I Inhibits the Metastasis of Cervical Cancer Through the Regulation of the β-Catenin Signaling Pathway., PMID:40429774
Transcriptomic Profiling of Hypoxia-Adaptive Responses in Tibetan Goat Fibroblasts., PMID:40427283
The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of changes in β-catenin abundance., PMID:40424469
SENP5 promotes endometrial cancer cell growth by regulating β-catenin deSUMOylation to enhance GPX4-resistance to ferroptosis., PMID:40410883
Exosomal lncRNA profiles in patients with HFrEF: Evidence for KLF3-AS1 as a novel diagnostic biomarker., PMID:40404068
Effect of chitosan nanoparticles conjugated with the cell free supernatant of Bifidobacterium bifidum on the expression of genes related to colorectal cancer in colon adenocarcinoma (Caco-2) cell line., PMID:40399800
CDX1 and CDX2 suppress colon cancer stemness by inhibiting β-catenin-facilitated formation of Pol II-DSIF-PAF1C complex., PMID:40399276
β-catenin is a Potential Prognostic Biomarker in Uterine Sarcoma., PMID:40398662
The human RNASET2 alarmin-like molecule differentially affects prostate cancer cells behavior in both cell autonomous and non-cell autonomous manners., PMID:40389981
Wnt/β-catenin activation by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary basal cell adenoma., PMID:40389436
Hepatic adenomas in males: Is molecular characterization helpful in guiding its management?, PMID:40379140
Role of genomic analysis in the classification of well differentiated hepatocellular lesions., PMID:40374146
UTX (KDM6A) promotes differentiation noncatalytically in somatic self-renewing epithelia., PMID:40372430
Quercetin-doped sol-gel coatings on titanium implants: a promising approach for enhanced immune response and cell adhesion., PMID:40371955
Pharmacological mechanisms of probenecid for SARS-CoV-2 and RSV co-infection: findings of system pharmacology, molecular docking, molecular dynamics simulation, and structure-activity relationship., PMID:40371107
AKT1 and CTNNB1 mutations as drivers of paclitaxel resistance in breast cancer cells., PMID:40370645
Protective effect of menthol against diethylnitrosamine-induced hepatocellular carcinoma in mice by downregulating CTNNB1 and HIF-1α., PMID:40365190
KLHL7 enhances cell viability and cell cycle progression in glioma via glutamine metabolism by activating the β-catenin signaling pathway., PMID:40353626
Differential Localization of β-Catenin Protein in CTNNB1 Mutant Endometrial Cancers Results in Distinct Transcriptional Profiles., PMID:40348058
High-Frequency Mutations in TP53, AXIN1, CTNNB1, and KRAS, and Polymorphisms in JAK1 Genes Among Mongolian HCC Patients., PMID:40344393
Molecular Subtype and Mutational Profile of Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia., PMID:40341112
Ctnnb1 and Keap1-Nrf2 mediating divergent heat resistance in two congeneric oysters., PMID:40334895
Crosstalk Between Wnt/β-Catenin and Hedgehog Supports Gli1+ Lineage Osteogenesis in Cranial Sutures., PMID:40332045
[Transcriptomic analysis of key genes involved in sex differences in intellectual development]., PMID:40326065
Hif-1α regulation of the Tet1-β-catenin-Dicer1-miRNAs pathway is involved in depression-like behavior in prenatal hypoxic male offspring., PMID:40318839
Ganoderic acid A: an in-depth review of pharmacological effects and molecular docking analysis., PMID:40316150
LncRNA SNHG1/miR-320b/CTNNB1 axis regulating the collective migration of fibroblasts in the formation of keloid., PMID:40314441
A structural element within the 5'UTR of β-catenin mRNA modulates its translation under hypoxia., PMID:40309781
Diagnostic insights into solid pseudopapillary neoplasms of the pancreas: a decade of experience with pediatric representation., PMID:40307756
Glycyrrhizic acid promotes liver regeneration through activating β-catenin in acetaminophen-induced liver injury., PMID:40306499
The differentiation of glial precursors into neuronal-like cells through the Wnt and Neurotrophin signaling pathways via Ctnnβ1., PMID:40302649
Prevalence of KCNJ5 mutations in aldosterone-producing adenomas among Malaysian primary aldosteronism patients: Genotype-phenotype correlation., PMID:40302475
Molecular characteristics and responses to EGFR tyrosine kinase inhibitors in non-small cell lung cancer patients with EGFR exon 19 insertions., PMID:40301895
Curcumin modulates β-catenin stabilization via targeting proteasomal deubiquitinating enzyme USP14☆., PMID:40294856
Ghost Cell Odontogenic Carcinoma of the Anterior Maxilla with ARID1A Mutation: A Case Report and Literature Review., PMID:40279034
Advanced organoid models for targeting Kras-driven lung adenocarcinoma in drug discovery and combination therapy., PMID:40275403
Genomic mutation and Clinicopathological features of KRAS wild-type tumors in Chinese cohort with pancreatic adenocarcinoma., PMID:40274200
For research use only. Not for human or drug use.
