Catalog No.
YHE04701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly81-Ala210
Predicted molecular weight
16.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P34130
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Neurotrophin-5, Neurotrophin-4, NT-4, NTF5, NTF4, Neutrophic factor 4, NT-5
[Corrigendum] Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy., PMID:39950318
The Complex Relationship between Neuromodulators, Circadian Rhythms, and Insomnia in Patients with Obstructive Sleep Apnea., PMID:39126038
Proteomics analysis of immune response-related proteins in Guillain-Barré Syndrome (GBS) and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)., PMID:39096562
Spatiotemporal regulation of dental pulpal innervation in the rat., PMID:39056435
Serum proteome signatures associated with ileal and colonic ulcers in Crohn's disease., PMID:38763457
Novel CAR-T cells targeting TRKB for the treatment of solid cancer., PMID:38498249
Evaluation of the Continuous Positive Airway Pressure Effect on Neurotrophins' Gene Expression and Protein Levels., PMID:38068919
Activation of MAPK-mediated immunity by phosphatidic acid in response to positive-strand RNA viruses., PMID:37434356
NTF4 plays a dual role in breast cancer in mammary tumorigenesis and metastatic progression., PMID:36632451
The Role of Neurotrophin-4/Forkhead Box L1 in the Development of Nonsmall-Cell Lung Cancer., PMID:36034210
Multiplex protein profiling of bronchial aspirates reveals disease-, mortality- and respiratory sequelae-associated signatures in critically ill patients with ARDS secondary to SARS-CoV-2 infection., PMID:35967328
Interactions Among Brain-Derived Neurotrophic Factor and Neuroimmune Pathways Are Key Components of the Major Psychiatric Disorders., PMID:35657457
Identification of genes and pathways associated with sex in Non-smoking lung cancer population., PMID:35577039
The role of neurotrophin genes involved in the vulnerability to gambling disorder., PMID:35484167
NTF4 stimulates the progression of gastric cancer via regulating FOXL1., PMID:34076998
Genetic Epidemiology of Primary Congenital Glaucoma in the 22 Arab Countries: A Systematic Review., PMID:33641569
Altered mRNA and lncRNA expression profiles in the striated muscle complex of anorectal malformation rats., PMID:32915273
Overexpression of α-Synuclein Reorganises Growth Factor Profile of Human Astrocytes., PMID:32914394
Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy., PMID:32236587
Maternal physical activity-induced adaptive transcriptional response in brain and placenta of mothers and rat offspring., PMID:31203831
Analysis of risk factors for colon cancer progression., PMID:31190895
Candidate genes involved in metastasis of colon cancer identified by integrated analysis., PMID:30884206
Correlation of metabolic parameters, neurotrophin-3, and neurotrophin-4 serum levels in women with schizophrenia and first-onset depression., PMID:30654674
Paeoniflorin improves pressure overload-induced cardiac remodeling by modulating the MAPK signaling pathway in spontaneously hypertensive rats., PMID:30611994
Detection of mutations in MYOC, OPTN, NTF4, WDR36 and CYP1B1 in Chinese juvenile onset open-angle glaucoma using exome sequencing., PMID:29540704
Role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing., PMID:29401709
Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer's disease., PMID:28888073
Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles., PMID:28654072
Genetic variants associated with primary open angle glaucoma in Indian population., PMID:27851990
Enhancement of aging rat laryngeal muscles with endogenous growth factor treatment., PMID:27207784
A proteomics approach to identify the differential protein level in cardiac muscle of diabetic rat., PMID:24918489
Mutation analysis of seven known glaucoma-associated genes in Chinese patients with glaucoma., PMID:24825108
Taste neurons consist of both a large TrkB-receptor-dependent and a small TrkB-receptor-independent subpopulation., PMID:24386206
Association of eNOS polymorphisms with primary angle-closure glaucoma., PMID:23422825
Serum neurotrophin concentrations in polish adolescent girls with anorexia nervosa., PMID:23221923
Neurotrophin serum concentrations and polymorphisms of neurotrophins and their receptors in children with asthma., PMID:23195334
Single ketamine infusion in bipolar depression resistant to antidepressants: are neurotrophins involved?, PMID:23124710
Evaluation of NTF4 as a causative gene for primary open-angle glaucoma., PMID:22815630
The genesis and unique properties of the lymphovascular tumor embolus are because of calpain-regulated proteolysis of E-cadherin., PMID:22580607
Retinal ganglion cell (RGC) death in glaucomatous beagles is not associated with mutations in p53 and NTF4 genes., PMID:22524196
Neurotrophin-4 regulates the survival of gustatory neurons earlier in development using a different mechanism than brain-derived neurotrophic factor., PMID:22353733
WDR36 variants in East Indian primary open-angle glaucoma patients., PMID:22025897
Genetics of primary glaucoma., PMID:21730848
Phosphorylation of the Nicotiana benthamiana WRKY8 transcription factor by MAPK functions in the defense response., PMID:21386030
Complex genetic mechanisms in glaucoma: an overview., PMID:21150032
Developmental expression of Bdnf, Ntf4/5, and TrkB in the mouse peripheral taste system., PMID:21038447
Identification of a novel mutation in the NTF4 gene that causes primary open-angle glaucoma in a Chinese population., PMID:20806036
Lingual and palatal gustatory afferents each depend on both BDNF and NT-4, but the dependence is greater for lingual than palatal afferents., PMID:20575060
Variations in NTF4, VAV2, and VAV3 genes are not involved with primary open-angle and primary angle-closure glaucomas in an indian population., PMID:20463313
Neurotrophin-4 (ntf4) mediates neurogenesis in mouse embryonic neural stem cells through the inhibition of the signal transducer and activator of transcription-3 (stat3) and the modulation of the activity of protein kinase B., PMID:20407817