Catalog No.
YHD85601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val201-Lys269
Predicted molecular weight
34.73 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P29972
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Aquaporin-CHIP, Urine water channel, AQP-1, Aquaporin-1, AQP1, CHIP28, Water channel protein for red blood cells and kidney proximal tubule
CBL-mediated AQP1 ubiquitination aggravates kidney-yang deficiency syndrome by promoting lipid metabolism dysregulation., PMID:40481542
Impaired Proteostasis is Linked to Neurological Pathology in a Zebrafish NGLY1 Deficiency Model., PMID:40470739
Role of channels in the O 2 permeability of murine red blood cells I. Stopped-flow and hematological studies., PMID:40463033
Role of channels in the O 2 permeability of murine red blood cells II. Morphological and proteomic studies., PMID:40462928
ANKHD1 promotes pathogenic proliferation in Autosomal Dominant Polycystic Kidney Disease via the Cyclin D1/CDK4 pathway., PMID:40457431
Interfering with AQP1 alleviates ferroptosis, improves mitochondrial function and energy metabolic disorder in hypoxia/reoxygenation-induced H9c2 cardiomyocytes via Wnt/β-catenin pathway., PMID:40436134
Renal tubular epithelial cell related partial epithelial-mesenchymal transition in AAⅠ induced renal fibrosis via Wnt7b/β-catenin signaling., PMID:40432885
Analysis of Kallikrein 6, Acetyl-α-Tubulin, and Aquaporin 1 and 2 Expression Patterns During Normal Human Nephrogenesis and in Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)., PMID:40428321
Impact of intermittent fasting versus vitamin D on high fat fructose-induced pancreatic steatosis: possible role of aquaporins., PMID:40419958
Osmotic Stress-induced Gene Expression in the Diencephalon, Kidney, Liver, and Breast Muscle of Chicks., PMID:40416751
PACAP inhibits sepsis-associated acute lung injury by inhibiting the Sp1/AQP1 pathway., PMID:40409714
Integrated transcriptomics and metabolomics unravel the key metabolic pathways involved in the therapeutic mechanism of Salvianic acid A against hepatic fibrosis., PMID:40389097
Exploring Renin-angiotensin System Genes as Novel Prognostic Biomarkers for Oral Squamous Cell Carcinoma., PMID:40386053
Acetazolamide as an aquaporin 1 inhibitor mitigates rheumatoid arthritis by reducing angiogenesis via the modulation of the FAK-PI3K/Akt signaling pathway., PMID:40359885
Decreased Expression of Alzheimer's Disease-Related Genes in Cancer May Contribute to the Inverse-Relationship-a Computational Study., PMID:40352571
Quantification of Urine and Plasma Levels of Extracellular Vesicles in a Cohort of Kidney Transplant Recipients and Chronic Kidney Disease Patients., PMID:40332150
Noninvasive DWI tracking of hiPSCs differentiation into RTECs in AKI recovery via the KSP promoter-mediated AQP1 strategy., PMID:40303334
A reversible fluorescence probe enables bioimaging and toxicity evaluation of lithium ion in living human cells., PMID:40267715
The prevalence of pathogenic variants in the BMPR2 gene in patients with the idiopathic pulmonary arterial hypertension in the Russian population: sequencing data and meta-analysis., PMID:40229839
Investigating the relationships of structural and functional neural networks of primary visual cortex with engineered AAVs and chemogenetic-fMRI techniques., PMID:40213659
Adequate salt intake is essential for candesartan-treated rats to maintain renal function., PMID:40204358
Aquaporin-1 acts as an O2 channel. The permeability of human and mouse red cell membranes for oxygen., PMID:40172004
New Perspective on Aqueous Humor Circulation: Retina Takes the Lead., PMID:40141285
AQP1 Affects Necroptosis by Targeting RIPK1 in Endothelial Cells of Atherosclerosis., PMID:40129682
Electroacupuncture attenuates intervertebral disc degeneration by upregulating aquaporins via the cAMP/PKA pathway., PMID:40128722
Assessing the link between skin Aquaporins and morphological attributes under simulated heat stress conditions: A comparative investigation between hair and wool sheep breeds., PMID:40117913
Ursodeoxycholic and chenodeoxycholic bile acids alleviate endotoxininduced acute lung injury in rats by modulating aquaporin expression and pathways associated with apoptosis and inflammation., PMID:40115259
CD24 is required for sustained transparency of the adult lens., PMID:40112946
Mechanism of CO 2 and NH 3 Transport through Human Aquaporin 1: Evidence for Parallel CO 2 Pathways., PMID:40093180
Role of channels in the O₂ permeability of murine red blood cells. III. Mathematical modeling and simulations., PMID:40093145
Decreased Expression of Aquaporins as a Feature of Tubular Damage in Lupus Nephritis., PMID:40072108
Effect of sex chromosome complement versus gonadal hormones on abundance of renal transporters., PMID:40062385
Multicilia dynamically transduce Sonic Hedgehog signaling to regulate choroid plexus functions., PMID:40057957
Exosome-Inspired Lipid Nanoparticles for Enhanced Tissue Penetration., PMID:40017353
Celastrol Mitigates Acetaminophen-Induced Nephrotoxicity in Rats via Targeting Renal Oxidative Stress, Inflammation, Apoptosis with Enhancement in Aquaporin 1 Level., PMID:39995643
The comprehensive potential of AQP1 as a tumor biomarker: evidence from kidney neoplasm cohorts, cell experiments and pan-cancer analysis., PMID:39988693
Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis., PMID:39977018
Exploring the correlation between magnetic resonance diffusion tensor imaging (DTI) parameters and aquaporin expression and biochemical composition content in degenerative intervertebral disc nucleus pulposus tissue: a clinical experimental study., PMID:39962475
The Expanding Role of Aquaporin-1, Aquaporin-3 and Aquaporin-5 as Transceptors: Involvement in Cancer Development and Potential Druggability., PMID:39941100
[Chemical composition and efficacy of warming lung and resolving fluid retention of Asarum forbesii grown under different shading conditions]., PMID:39929619
Genome-wide identification of aquaporin and their potential role in osmotic pressure regulation in Ruditapes philippinarum., PMID:39929021
Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes., PMID:39915484
Advanced diffusion-weighted imaging-derived quantitative parameters as biomarkers of fibrosarcoma-cell proliferation in nude mice: A study based on precise imaging-pathology correlation., PMID:39892483
Bacopaside I, acting as an aquaporin 1 inhibitor, ameliorates rheumatoid arthritis via suppressing aquaporin 1-mediated autophagy., PMID:39892307
Tiaogeng decoction improves mild cognitive impairment in menopausal APP/PS1 mice through the ERs/NF-κ b/AQP1 signaling pathway., PMID:39848022
In silico drug repurposing at the cytoplasmic surface of human aquaporin 1., PMID:39787482
Silencing aquaporin 1 inhibits autophagy to exert anti-rheumatoid arthritis effects in TNF-α-induced fibroblast-like synoviocytes and adjuvant-induced arthritis rats., PMID:39774992
Aquaporin‑1 regulates microglial polarization and inflammatory response in traumatic brain injury., PMID:39749692
Efficacy and Fate of RNA Interference Molecules in the Green Pea Aphid, Acyrthosiphon pisum., PMID:39726327
Advancements of aquaporin 1 in ultrafiltration failure secondary to peritoneal dialysis., PMID:39724420